Results 171 to 180 of about 4,028,214 (240)

Walhonding Canal Triple Locks

open access: yes
One black and white photographic print of the remains of a canal boat sitting in the Walhonding Canal Triple Locks in Roscoe Village in Coshocton County, Ohio. The Walhonding Canal was a small feeder canal for the Ohio and Erie Canal in Coshocton County,
Canal Society of Ohio
core  

CaMKIIδ Phosphorylates AUP1 to Promote Pancreatic Tissue Repair and Acinar‐to‐Ductal Metaplasia Formation via Mediating PERK‐Dependent Unfolded Protein Responses

open access: yesAdvanced Science, EarlyView.
CaMKIIδ–AUP1 signaling maintains PERK‐dependent ER homeostasis during ADM‐mediated pancreatic repair. ABSTRACT Pancreatic repair after acute pancreatitis (AP) is essential for restoring tissue integrity, but the intrinsic mechanisms coordinating acinar plasticity and regeneration remain poorly understood.
Yonghao Chen   +10 more
wiley   +1 more source

Unidentified Canal Lock Remains 5

open access: yes
One black and white photographic slide of an unidentified canal lock on the canal, probably the Ohio and Erie Canal in eastern Ohio. A train sits on a railroad to the right of the canal.
Canal Society of Ohio
core  

Biomimetic Nanoplatform for Fibrosis Remodeling and Anti‐PD‐1 Potentiation via Cu+/Ca2+ Ion Dysregulation and TGF‐β Inhibition in PDAC

open access: yesAdvanced Science, EarlyView.
A biomimetic nanoplatform (RPm@CC‐LY) remodels fibrotic stroma via sustained TGF‐β inhibition, triggers oxidative stress and apoptosis through Cu+‐mediated Fenton chemistry and Ca2+ overload, and reprograms macrophages and dendritic cells to boost CD8+ T cell infiltration.
Jianmei Li   +6 more
wiley   +1 more source

Unidentified Canal Lock Remains 1

open access: yes
One color photographic slide of the remains of an unidentified canal lock on a canal, probably the Ohio and Erie Canal or Dresden Side-Cut Canal. A dirt path cross the foreground and grass and shrubbery grows around the lock walls.
Canal Society of Ohio
core  

Molecular MRI Reveals Macrophage‐Enriched Peritumoral Immune Remodeling After Incomplete Ablation in Liver Cancer

open access: yesAdvanced Science, EarlyView.
Incomplete microwave ablation (iMWA) induced a spatially organized, macrophage‐rich immunosuppressive tumor microenvironment (TME) in orthotopic VX2 liver tumors. Molecular MRI enhanced with europium‐doped very small superparamagnetic iron oxide nanoparticles (Eu‐VSOP) noninvasively visualized this remodeling, showing preferential nanoparticle ...
Yubei He   +22 more
wiley   +1 more source

Rethinking Cochlear Implants: The Need for Precise Temporal Coding

open access: yesAdvanced Science, EarlyView.
Spatial hearing relies on sensitivity to interaural temporal cues, but this sensitivity is often poorly developed in patients with cochlear implants, particularly those with early‐onset hearing loss. Rats with cochlear implants, however, demonstrate excellent temporal sensitivity, suggesting that this limitation is not inevitable.
Nicole Rosskothen‐Kuhl   +1 more
wiley   +1 more source

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