Results 101 to 110 of about 2,664 (184)

Primary intracranial atypical teratoid/rhabdoid tumor in a child with Canavan disease.

, 1995
A primary intracranial atypical teratoid/rhabdoid tumor was encountered in a child (age 4 years and 9 months) with Canavan disease. The tumor contained a large spindled cell component as well as classical rhabdoid morphology and focal areas resembling a ...
Yachnis, A T, Rorke, L B, Manhoff, D T
core  

The epidemiology of irritable bowel syndrome

Clinical Epidemiology, 2014
Caroline Canavan, Joe West, Timothy Card Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK Abstract: Irritable bowel syndrome (IBS) is a functional condition of the bowel that is diagnosed using clinical criteria. This
Canavan C, West J, Card T
doaj  

Management of Fracture Risk in Patients with Chronic Obstructive Pulmonary Disease (COPD): Building a UK Consensus Through Healthcare Professional and Patient Engagement

International Journal of COPD, 2020
Ayushman Gupta, 1 Leah R Jayes, 2 Steve Holmes, 3 Opinder Sahota, 4 Melissa Canavan, 5 Sarah L Elkin, 6 Kelvin Lim, 7 Anna C Murphy, 8 Sally Singh, 9, 10 Elizabeth A Towlson, 11 Helen Ward, 12 Jane Scullion, 9 Tricia M McKeever, 2 Charlotte E Bolton 1 ...
Gupta A, Jayes LR, Holmes S, Sahota O, Canavan M, Elkin SL, Lim K, Murphy AC, Singh S, Towlson EA, Ward H, Scullion J, McKeever TM, Bolton CE   +13 more
doaj  

Cribriform Appearance of White Matter in Canavan Disease Associated with Novel Mutations of ASPA Gene. [PDF]

J Pediatr Genet, 2022
Bhat MD, Manjunath N, Kumari R, Faruq M, Pal PK, Prasad C, Mundlamuri RC, Nalini A, Udupi GA, Baishya PP, Kulanthaivelu K.   +10 more
europepmc   +1 more source

The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes

, 2009
Elevations of the levels of N-acetyl-aspartyl-glutamate (NAAG) and N-acetyl-aspartate (NAA) are associated with myelin loss in the leucodystrophies Canavan's disease and Pelizaeus-Merzbacher-like disease. NAAG and NAA can activate and antagonize neuronal
Attwell, D., Koodziejczyk, Karolina, Kolodziejczyk, K., Wade, A., Kradttir, Ragnhildur, Wade, Anna, Karadottir, R., Hamilton, Nicola B.; id_orcid, Attwell, David, Hamilton, N. B.   +9 more
core   +1 more source

N-acetylaspartate mitigates pro-inflammatory responses in microglial cells by intersecting lipid metabolism and acetylation processes

Cell Communication and Signaling
Background Microglia play a crucial role in brain development and repair by facilitating processes such as synaptic pruning and debris clearance.
Federica Felice, Pamela De Falco, Martina Milani, Serena Castelli, Antonella Ragnini-Wilson, Giacomo Lazzarino, Nadia D’Ambrosi, Fabio Ciccarone, Maria Rosa Ciriolo   +8 more
doaj   +1 more source

High Throughput Screening Cascade To Identify Human Aspartate N-Acetyltransferase (ANAT) Inhibitors for Canavan Disease. [PDF]

ACS Chem Neurosci, 2021
Nešuta O, Thomas AG, Alt J, Hin N, Neužilová A, Long S, Tsukamoto T, Rojas C, Wei H, Slusher BS.   +9 more
europepmc   +1 more source

A case of Canavan disease with normocephaly - A rare entity

, 2017
Canavan disease (CD) is an autosomal recessive disorder with spongy degeneration of white matter of the brain. It typically presents with developmental delay, visual problems, and macrocephaly.
Meena, Sangeeta, Hassan, Shamsuddin, Bajaj, Srilatha, Mina, Shyam Sundar   +3 more
core  

Targeted Therapy for Canavan Disease Illuminated by Subcellular Spatiotemporal Multi-omics

Demyelinating disorders, including multiple sclerosis and Canavan disease, afflict millions worldwide, yet their underlying mechanisms remain largely elusive.
Wang, Yongheng
core  

Physioteherapy assessment of canavan disease: Case report

, 2015
Background: This study aimed to present symptoms related to physiotherapy of Canavan Disease (CD) and evaluation of these symptoms. Methods: In physiotherapy evaluations of the child included gross motor function measurement (GMFCS), muscle tone ...
Duray, M, Altuğ, Filiz, Kılavuz, G
core