Results 141 to 150 of about 7,224,511 (260)

Patient voice in cancer research: patient workshop and discussion groups.

, 2019
The National Cancer Strategy 2017-2026 sets out the vision for delivery of cancer services in Ireland. Central to the strategy is that services be in place to better serve the needs of cancer patients.
National Cancer Registry Ireland (NCRI)
core  

Cancer Research UK Cancer Awareness Measures, 2017

, 2020
copyright UK Data Service and data collection copyright owner.The Cancer Awareness Measure (CAM) was developed in 2007-8 to address the absence of a validated measure of general public awareness of cancer (Stubbings, S., Robb, K., Waller, J., Ramirez, A.,
Cancer Research UK
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Opioid Use and Family Members' Experiences of Opioids in Paediatric Cancer Pain Management: An Integrative Review. [PDF]

Scand J Caring Sci
Puusa N, Harju E, Kalliomäki ML, Haavisto E.   +3 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

CRISPR-Cas9 Screening Identifies KRAS-Induced COX2 as a Driver of Immunotherapy Resistance in Lung Cancer.

Oncogenic KRAS impairs antitumor immune responses. As effective strategies to combine KRAS inhibitors and immunotherapies have so far proven elusive, a better understanding of the mechanisms by which oncogenic KRAS drives immune evasion is needed to ...
East, P, Cha, H, Rana, S, Moore, C, Mugarza, E, de Carné Trécesson, S, Tomaschko, M, Anastasiou, P, Molina-Arcas, M, Boumelha, J, Lee, S-H, Litchfield, K, Downward, J, de Castro, A, Bah, N, Goldstone, R   +15 more
core   +1 more source

Nonlinear Aging of the Human TCR Repertoire Is Influenced by Sex, CMV, and Cancer. [PDF]

Aging Cell
Lange N, Attermann AK, Juul RI, Andersen L, Nordentoft I, Jessen LE, McGranahan N, Aerts HJWL, Dyrskjøt L, Birkbak NJ.   +9 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Japanese Society for Hereditary Tumors Guidance: Hereditary Cancer Syndromes With Multigene Panel Testing, 2025 Edition. [PDF]

Cancer Sci
Yoshida R, Hirasawa A, Imoto I, Yamaguchi T, Kumamoto K, Momoko A, Ueki A, Masuda K, Urakawa Y, Tanabe N, Watanabe A, Hirata M, Aruga T, Kuwata T, Okugawa Y, Kaneko K, Terui-Kohbata H, Matsumoto M, Ueno S, Oda K, Ono H, Sakurai A, Matsui H, Yamamoto G, Yamamoto H, Yamamoto Y, Ikegami M, Ohkuma Y, Shien K, Suzuki S, Takayanagi S, Tanabe M, Hasumi H, Hatta N, Hattori H, Matsubayashi H, Yamagami W, Yamada M, Oishi K, Oka T, Oda S, Kobayashi Y, Takekoshi K, Nakajima T, Nakano Y, Nakayama Y, Miura F, Miyakura Y, Mori Y, Yoshimura A, Yonamine M, Shigeyasu K, Fujita H, Futagawa M, Ohta K, Kawano J, Tokutomi T, Sato A, Makabe T, Yoshihama T, Aitani M, Kimura K, Takaiso N, Tomozawa C, Hiraoka Y, Matsukawa M, Ishida H.   +66 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source