Results 181 to 190 of about 12,006,097 (356)

The Functions and Unique Features of LncRNAs in Cancer Development and Tumorigenesis [PDF]

, 2021
Kenzui Taniue, Nobuyoshi Akimitsu
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Photodynamic therapy in cancer treatment - an update review

, 2019
Ancély Ferreira dos Santos, Daria Raquel Queiroz de Almeida, Letícia Ferreira Terra, Maur��cio S. Baptista, Letícia Labriola   +4 more
openalex   +2 more sources

Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease–Associated Colorectal Cancer [PDF]

, 2021
Kristiina Rajamäki, Aurora Taira, Riku Katainen, Niko Välimäki, Anna Kuosmanen, Roosa-Maria Plaketti, Toni T. Seppälä, Maarit Ahtiainen, Erkki‐Ville Wirta, Emilia Vartiainen, Päivi Sulo, Janne Ravantti, Suvi Lehtipuro, Kirsi J. Granberg, Matti Nykter, Tomas Tanskanen, Ari Ristimäki, Selja Koskensalo, Laura Renkonen‐Sinisalo, Anna Lepistö, Jan Böhm, Jussi Taipale, Jukka‐Pekka Mecklin, Mervi Aavikko, Kimmo Palin, Lauri A. Aaltonen   +25 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Global incidence of lip, oral cavity, and pharyngeal cancers by subsite in 2022. [PDF]

CA Cancer J Clin
Rumgay H, Colombet M, Ramos da Cunha A, Filho AM, Warnakulasuriya S, Conway DI, Chaturvedi A, Virani S, Lauby-Secretan B, Carvalho AL, Nethan ST, Jemal A, Bray F.   +12 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Cancer [PDF]

, 2005
openaire   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Metformin Inhibits Cell Proliferation, Migration and Invasion by Attenuating CSC Function Mediated by Deregulating miRNAs in Pancreatic Cancer Cells

, 2011
Bin Bao, Zhiwei Wang, Shadan Ali, Aamir Ahmad, Asfar S. Azmi, Sanila H. Sarkar, Sanjeev Banerjee, Dejuan Kong, Yiwei Li, Shivam Thakur, Fazlul H. Sarkar   +10 more
openalex   +2 more sources