Results 341 to 350 of about 17,238,138 (390)

A novel cancer gene therapy achieving reciprocal regulation of PTEN and PARP1 expression. [PDF]

Mol Ther Oncol
Otsuka Y, Watanabe T, Kudo M.
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Industrial point source emissions and incident breast and lung cancers: two case-control studies. [PDF]

Cancer Causes Control
Boyle J, Nana-Sinkam P, McGuire KP, Fuemmeler BF.   +3 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Modifiable and Nonmodifiable Risk Factors for Breast Cancer: A Comprehensive Scoping Review. [PDF]

Int J Breast Cancer
Momenimovahed Z, Shahabinia Z, Allahqoli L, Salehiniya H.   +3 more
europepmc   +1 more source

Retraction Note: Epigenetic modification of ferroptosis by non-coding RNAs in cancer drug resistance. [PDF]

Mol Cancer
Wang H, Fleishman JS, Cheng S, Wang W, Wu F, Wang Y, Wang Y.   +6 more
europepmc   +1 more source

Subsequent primary neoplasm risk among survivors of cancer in adolescence and young adulthood: a population-based study from Alberta, Canada. [PDF]

CMAJ
Ul Alam A, Tchir D, McKillop S, Logie N, Cavanaugh T, Nathan PC, Reynolds KA, Fidler-Benaoudia MM.   +7 more
europepmc   +1 more source