Results 81 to 90 of about 10,935,890 (352)

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Cancer cachexia [PDF]

open access: yesBritish Journal of Cancer, 1991
Cachexia is a common problem in the clinical management of cancer patients, particularly those with solid tumors. Cachexia is most obviously manifested as weight loss with massive depletion of both adipose tissue and muscle mass, and death is probably due to loss of lean body tissue.
openaire   +5 more sources

Criteria weighting by using the 5Ws & H technique

open access: yesBusiness Systems Research, 2012
Background: This paper introduces the use of the 5Ws & H technique, which is the creative problem solving technique based on who, what, when, where, why and how questions, for the establishing of the criteria weights in multi-criteria decision-making ...
Vesna Čančer
doaj  

Leucemias Agudas na Infância e Adolescência

open access: yesRevista Brasileira de Cancerologia, 2001
Conduta diagnóstico-terapêutica do INCA para Leucemias Agudas na Infância e Adolescência.
Instituto Nacional de Câncer
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Kinases and Cancer [PDF]

open access: yesCancers, 2018
Protein kinases are a large family of enzymes catalyzing protein phosphorylation. The human genome contains 518 protein kinase genes, 478 of which belong to the classical protein kinase family and 40 are atypical protein kinases [...]
Jonas Cicenas   +3 more
openaire   +5 more sources

Considering Interactions among Multiple Criteria for the Server Selection

open access: yesJournal of Information and Organizational Sciences, 2010
Decision-making about server selection is one of the multi-criteria decision-making (MCDM) processes where interactions among criteria should be considered.
Vesna Čančer
doaj  

BIREME: A informação ao seu alcance

open access: yesRevista Brasileira de Cancerologia, 2023
A BIBLIOTECA REGIONAL DE MEDICINA (BIREME) foi criada para dar melhor atendimento à pesquisa médica na América Latina, colocando ao alcance do profissional todas as facilidades existentes no campo da moderna informação biomédica.
Divisão Nacional de Câncer
doaj  

Prevenção do câncer do colo do útero

open access: yesRevista Brasileira de Cancerologia, 2003
Extrato do artigo: Prevenção e controle do câncer: normas e recomendações do INCA, publicado na Rev Bras Cancerol 2002;48(3):317-32.
Instituto Nacional de Câncer
doaj   +1 more source

The Cancer Genome Atlas Pan-Cancer analysis project

open access: yesNature Genetics, 2013
Current clinical practice is organized according to tissue or organ of origin of tumors. Now, The Cancer Genome Atlas (TCGA) Research Network has started to identify genomic and other molecular commonalities among a dozen different types of cancer ...
J. Weinstein   +8 more
semanticscholar   +1 more source

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