Results 61 to 70 of about 149,609 (268)

Evaluating an Enterprise-Wide Initiative to enhance healthcare coordination for rural women Veterans using the RE-AIM framework

Frontiers in Health Services
IntroductionThe Veterans Health Administration (VA) Office of Rural Health (ORH) and Office of Women's Health Services (OWH) in FY21 launched a three-year Enterprise-Wide Initiative (EWI) to expand access to preventive care for rural, women Veterans ...
Mark R. Relyea, Mark R. Relyea, Rebecca L. Kinney, Rebecca L. Kinney, Eric C. DeRycke, Sally Haskell, Sally Haskell, Kristin M. Mattocks, Kristin M. Mattocks, Lori A. Bastian, Lori A. Bastian   +10 more
doaj   +1 more source

Pilot Survey of Breast Cancer Management in Sub-Saharan Africa

Journal of Global Oncology, 2017
Purpose: To understand the current state of breast cancer management in sub-Saharan Africa. Methods: We conducted an anonymous online survey of breast cancer management among African Organization for Research and Treatment in Cancer (AORTIC) members by ...
Verna D.N.K. Vanderpuye, Olufunmilayo I. Olopade, Dezheng Huo   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

How Architects and Clients Integrate User Perspectives in Cancer Care Facility Design

, 2021
Objective – This paper seeks to investigate the extent to which architects and clients involved in the design of cancer care facilities integrate the perspectives of users generally, and people affected by cancer specifically, in the design process. Background – Increasingly hospital users contribute to design briefs and participate as stakeholders in ...
Jellema, Pleuntje, Annemans, Margo, Heylighen, Ann   +2 more
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Patient driven care in the management of prostate cancer: analysis of the United States military healthcare system

BMC Urology, 2017
Background Patient preferences are assumed to impact healthcare resource utilization, especially treatment options. There is limited data exploring this phenomenon.
Muhammad Ali Chaudhary, Jeffrey J. Leow, Matthew Mossanen, Ritam Chowdhury, Wei Jiang, Peter A. Learn, Joel S. Weissman, Steven L. Chang   +7 more
doaj   +1 more source

Cancer Survivorship Care in the United States at Facilities Accredited by the Commission on Cancer

JAMA Network Open
ImportanceSince 2021, American College of Surgeons Commission on Cancer (CoC) accreditation standards require providing a survivorship program for patients with adult-onset cancer treated with curative intent. Since more than 70% of all patients with cancer in the US are treated at CoC-accredited facilities, this presents an opportunity for a landscape
Stal, Julia, Miller, Kimberly A., Mullett, Timothy W., Boughey, Judy C., Francescatti, Amanda B., Funk, Elizabeth, Nelson, Heidi, Freyer, David R.   +7 more
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Role of digital health in coordinating patient care in a hub-and-spoke hierarchy of cancer care facilities: a scoping review. [PDF]

Ecancermedicalscience, 2023
Venkataramanan R, Pradhan A, Kumar A, Alajlani M, Arvanitis TN.   +4 more
europepmc   +1 more source