Results 71 to 80 of about 479,049 (311)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Facilitating equity-oriented cancer care in organizations delivering cancer services: insights from a qualitative study

Frontiers in Oncology
BackgroundPeople experiencing structural marginalization often have advanced cancer diagnoses and higher cancer-related mortality resulting, in part, from poor access to care.
Tara C. Horrill, Jess Crawford, Scott M. Beck, Amber Bourgeois, Amber Bourgeois, Jagbir Kaur, Leah K. Lambert, Leah K. Lambert, Michael McKenzie, Kelli I. Stajduhar, Annette J. Browne   +10 more
doaj   +1 more source

Designing emotion-centred Product Service Systems: The case of a cancer care facility [PDF]

Design Studies, 2015
Product Service Systems (PSS) designers are increasingly signaling the importance of emotion. However, emotion is yet to be theoretically and empirically studied in PSS design. This paper offers a conceptual model as well as an in-depth field study of the design of an emotion-centred PSS.
Patrick Keith Stacey, Bruce S. Tether
openaire   +2 more sources

Quality of Care Facts and Figures 2009 [PDF]

, 2009
Summarizes the performance of the state's healthcare system compared with national averages on ten quality measures, including maternal and child health; cancer, diabetes, and heart disease care; re-hospitalization rates; and care for ...
Jennifer Joynt
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Associations between quality of life and health literacy in a Norwegian urban cancer population—a cross-sectional study

Health Literacy and Communication Open
Background Cancer presents challenges for patients due to its complexity and treatment demands, resulting in a low quality of life. Patients must manage amounts of information, and make care decisions.
Marit Leine, Astrid K. Wahl, Simen A. Steindal, Åsmund Hermansen, Martha P. Lein, Milada Hagen, Caryl Gay, Kjell Magne Tveit, Christine R. Borge   +8 more
doaj   +1 more source

Geographic distribution of health services in the breast cancer care pathways in Pernambuco, Northeast of Brazil [PDF]

Revista Brasileira de Saúde Materno Infantil
Objectives: to analyze the geographic distribution of breast cancer care services in Pernambuco, northeastern Brazil. Methods: a descriptive cross-sectional study analyzing the geographic distribution of breast cancer care services, which used the ...
Rosalva Raimundo da Silva, Iris Edná Pereira da Silva, Geyssyka Morganna Soares Guilhermino, Wisley Donizetti Velasco, Isabel Cristina Areia Lopes Pereira, Tereza Maciel Lyra   +5 more
doaj   +1 more source

OR Air Quality: Is it time to consider adjunctive air cleaning technology? [PDF]

, 2018
Patients undergoing surgery may be at risk for infection from airborne particles such as dust, skin scales, respiratory aerosols, and hair fibers emanating from multiple sources in the OR, including personnel, heater-cooler devices,and surgical smoke ...
Barnes, Sue, Carrico, Ruth, Murphy, Cathryn, Twomey, Carolyn, Warye, Kathy   +4 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Comparison of Knowledge, Attitude, and Practices of Nursing Staff Regarding Cervical Cancer Screening at Various Levels of Health Care Facilities in Western India

Indian Journal of Community Medicine
Background: Cervical cancer is a public health problem, and nursing personnel are crucial for successful implementation of low-cost cervical cancer screening approaches in low-resource settings.
Rashmi Kaushal, Mamta Patel, Pankaj Bhardwaj, Manoj Gupta, Deepti Mathur, Girish Chandra Dash, Shashank Shekhar   +6 more
doaj   +1 more source