Results 91 to 100 of about 154,638 (269)

A Molecular Shielding Strategy to Develop Low Protein Binding, Renal Clearable Pan‐Cancer Near‐Infrared Probes

Advanced Functional Materials, EarlyView.
A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang, Kailin Mooney, Mingchong Dai, Morgan R. Stewart, Samantha Holland, Michael I. Henderson, Samuel Drennan, Ramon F. Barajas Jr., Jared M. Fischer, Adem Yildirim   +9 more
wiley   +1 more source

Artery‐on‐Chip Demonstrates Mechanical and Functional Features of Healthy and Diseased Living Smooth Muscle Tissue

Advanced Functional Materials, EarlyView.
This article details the development of an artery‐on‐chip platform for in vitro arterial disease modeling and therapeutic discovery. It describes the fabrication of a fibrin biomaterial scaffold seeded with iPSC‐derived smooth muscle and endothelial cells, mimicking native artery properties. Two genetic disease models showcase the platform's ability to
Danielle Yarbrough, Roy Chen, Katerina Katsouleas, Jaron Shoemaker, Travis Brady, Tianfang Yu, Jennifer Arthur Ataam, Connor Amelung, Lakshmi Santhanam, Ioannis Karakikes, Sharon Gerecht   +10 more
wiley   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Health facility assessments of cervical cancer prevention, early diagnosis, and treatment services in Gulu, Uganda

PLOS Global Public Health, 2023
Background Cervical cancer is ranked globally in the top three cancers for women younger than 45 years, with the average age of death at 59 years of age.
Tana Chongsuwat, Aaliyah O. Ibrahim, Ann E. Evensen, James H. Conway, Margaret Zwick, William Oloya   +5 more
doaj  

Sustainable Electrochemical Synthesis of High‐Quality MXenes: Mechanistic Insights, Applications, Challenges, and Technological Prospects

Advanced Functional Materials, EarlyView.
Electrochemical etching provides an eco‐friendly alternative to hazardous HF methods for MXene production. This approach facilitates the selective isolation of the A‐layer from MAX phases with tunable surface terminations. Controlling voltage, electrolytes, temperature, and duration enables the optimal structural integrity. Nevertheless, existing scale
Jagdeep Singh, Madhusudhana M Devadiga, Santosh K. Tiwari, AS Dhaliwal, Gurpreet Singh Selopal   +4 more
wiley   +1 more source

Breast cancer surgical services in South Africa: Availability and barriers to guideline-concordant care

South African Medical Journal
Background. Female breast cancer has become the most frequently diagnosed cancer globally. The incidence of cancer in South Africa (SA) is projected to double by 2030, and services to address the growing burden of disease are urgently needed.
L Milligan, L Roodt, F Malherbe, L Cairncross   +3 more
doaj   +1 more source

Demystifying cervical cancer care pathways in private facilities in Kenya

Abstract Background Despite advances in HPV vaccination and screening technologies, the uptake of these preventive measures remains low in Kenya, particularly within private healthcare settings. This study evaluates the integration of routine HPV testing into cervical cancer screening programs in private facilities across Kenya ...
Samuel M. Mbugua, Mary Kioko, Cynthia Munene, Brian Lishenga, Jesse Gitaka   +4 more
openaire   +1 more source

Glucose Deprivation‐Driven Concurrent Induction of Apoptosis/Disulfidptosis/Ferroptosis by Tumor Targeting Nanoassemblies in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Innovative hybrid nanoassemblies installed with ferrocene, D‐α‐tocopherol succinate, and phloretin exploit the metabolic vulnerability of triple‐negative breast cancer under glucose starvation. By blocking glucose uptake, this single nanoplatform simultaneously orchestrates apoptosis, disulfidptosis, and ferroptosis to achieve synergistic and ...
Song Yi Lee, ChaeRim Hwang, Seong Eun Kim, Mrinmoy Karmakar, Seo Jin Jung, Hyeonseok Jang, Hae‐In Kim, Heejung Yang, Junmin Lee, Dae‐Duk Kim, Hyun‐Jong Cho   +10 more
wiley   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

Association between multiple dimensions of access to care and cervical cancer screening among Kenyan women: a cross-sectional analysis of the Demographic Health Survey

BMC Health Services Research
Background Cervical cancer remains the second most common cause of death in women and poses a growing public health challenge. It is urgent to increase cervical cancer screening rates in Kenya as per the 2018 Kenya National Cancer Screening Guidelines ...
Xiaowan Li, Sanmei Chen, Naoki Hirose, Yoko Shimpuku   +3 more
doaj   +1 more source