Results 11 to 20 of about 2,753,395 (319)
Cell Motility and Cancer [PDF]
Cell migration is an essential systemic behavior, tightly regulated, of all living cells endowed with directional motility that is involved in the major developmental stages of all complex organisms such as morphogenesis, embryogenesis, organogenesis, adult tissue remodeling, wound healing, immunological cell activities, angiogenesis, tissue repair ...
Ildefonso M. De la Fuente +2 more
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Stem cells, cancer, and cancer stem cells [PDF]
Stem cell biology has come of age. Unequivocal proof that stem cells exist in the haematopoietic system has given way to the prospective isolation of several tissue-specific stem and progenitor cells, the initial delineation of their properties and expressed genetic programmes, and the beginnings of their utility in regenerative medicine.
Sean J. Morrison +4 more
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Abstract In this review, we overview the main features and functions of NK cells, focusing on their role in cell-mediated immune response to tumor cells. In parallel, we discuss the information available in the field of NK cell receptors and offer a wide general overview of functional aspects of cell targeting and killing, focusing on ...
Zamai L +7 more
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During cancer progression, cells lose their original tissue contacts, move through the extracellular matrix (ECM), enter into the lymphatic and/or blood system, extravasate, and ultimately form new tumors. Therefore, tumor cells inevitably experience alterations in cell-cell and cell-ECM adhesion and the transformation activities of tumor cells are ...
Eok-Soo Oh +3 more
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T-cell clonotypes in cancer [PDF]
Cells of the immune system spontaneously recognize autologous tumor cells and T cells are believed to be the main effector cells for the immune surveillance of cancer. Recent advances in our understanding of basic and tumor immunology together with methodological developments implies that tumor specific T cells can now be studied functionally ...
Per thor Straten +3 more
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Cancer metabolism has been of interest for decades; however, the recent development of sophisticated techniques such as metabolomics or lipidomics have significantly increased our understanding of processes taking place in tumour cells [...]
Parkinson, Eric K. +2 more
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T Cell Dysfunction in Cancer [PDF]
Therapeutic reinvigoration of tumor-specific T cells has greatly improved clinical outcome in cancer. Nevertheless, many patients still do not achieve durable benefit. Recent evidence from studies in murine and human cancer suggest that intratumoral T cells display a broad spectrum of (dys-)functional states, shaped by the multifaceted suppressive ...
Thommen, Daniela S., Schumacher, Ton N.
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The concept of cancer stem cells has generated significant interests among cancer researchers. This has led to proliferative number of publications on the subject in the recent years and eventually controversies because of conflicting data in the literature.
Bo Lu +3 more
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Cell plasticity in cancer cell populations [PDF]
In this review, we propose a recension of biological observations on plasticity in cancer cell populations and discuss theoretical considerations about their mechanisms.
Shensi Shen, Jean Clairambault
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Impact of Carbon Fluoroxide Nanoparticles on Cell Proliferation
Cytotoxicity of fluorescent carbon fluoroxide (CFO) nanoparticles (NPs) was studied in a label-free manner on several cancer and non-cancer cell lines. A direct cytotoxic effect of the CFO NPs was clearly observed by a suppression of cell proliferation ...
Alain Géloën +5 more
doaj +1 more source

