Results 11 to 20 of about 16,222,859 (319)
Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy
Nature Biomedical Engineering, 2021 Malignant transformation and tumour progression are associated with cancer-cell softening. Yet how the biomechanics of cancer cells affects T-cell-mediated cytotoxicity and thus the outcomes of adoptive T-cell immunotherapies is unknown.
Kewen Lei +15 more
semanticscholar +1 more source
Metabolic reprogramming of cancer-associated fibroblasts and its effect on cancer cell reprogramming
Theranostics, 2021 Cancer cells are well-known for adapting their metabolism to maintain high proliferation rates and survive in unfavorable environments with low oxygen and nutritional deficiency.
Zhenzhen Li, Chanjun Sun, Zhihai Qin
semanticscholar +1 more source
Novel Roles of Nanog in Cancer Cells and Their Extracellular Vesicles
Cells, 2022 The use of extracellular vesicle (EV)-based vaccines is a strategically promising way to prevent cancer metastasis. The effective roles of immune cell-derived EVs have been well understood in the literature.
Mikako Saito
doaj +1 more source
In Vitro Anticancer Drug Sensitivity Sensing through Single-Cell Raman Spectroscopy
Biosensors, 2021 Traditional in vitro anticancer drug sensitivity testing at the population level suffers from lengthy procedures and high false positive rates. To overcome these defects, we built a confocal Raman microscopy sensing system and proposed a single-cell ...
Jingkai Wang +7 more
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The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity
Nature, 2012 The systematic translation of cancer genomic data into knowledge of tumour biology and therapeutic possibilities remains challenging. Such efforts should be greatly aided by robust preclinical model systems that reflect the genomic diversity of human ...
J. Barretina +60 more
semanticscholar +1 more source
A metastasis map of human cancer cell lines
Nature, 2020 Most deaths from cancer are explained by metastasis, and yet large-scale metastasis research has been impractical owing to the complexity of in vivo models.
Xin Jin +18 more
semanticscholar +1 more source
Lipid composition of the cancer cell membrane
Journal of Bioenergetics and Biomembranes, 2020 Cancer cell possesses numerous adaptations to resist the immune system response and chemotherapy. One of the most significant properties of the neoplastic cells is the altered lipid metabolism, and consequently, the abnormal cell membrane composition ...
W. Szlasa +4 more
semanticscholar +1 more source
A guide to cancer immunotherapy: from T cell basic science to clinical practice
Nature reviews. Immunology, 2020 The T lymphocyte, especially its capacity for antigen-directed cytotoxicity, has become a central focus for engaging the immune system in the fight against cancer.
A. Waldman, Jill M. Fritz, M. Lenardo
semanticscholar +1 more source
Frontiers in Oncology, 2021 The mitochondria play a significant role in many cellular processes and are recognized as one of the most important therapeutic targets in cancer. Direct long-term imaging of the mitochondria is very crucial for treating cancer.
Qin Jiang +7 more
doaj +1 more source
Diagnosis and treatment of the Cancer Tumor Cells (CTCs); Capturing and Diagnosing Kits [PDF]
Nanomedicine Research Journal, 2019 Objective(s): In the developed countries, one of the leading causes of death is cancer. Cancer cells with their unique and destructive characteristics impose high costs on communities.
Ali Alirezaie Alavijeh +3 more
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