Results 11 to 20 of about 18,416,887 (403)
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways [PDF]
, 2014 Most cancer cells use aerobic glycolysis to fuel their growth. The enzyme lactate dehydrogenase-A (LDH-A) is key to cancer’s glycolytic phenotype, catalysing the regeneration of nicotinamide adenine dinucleotide (NAD þ ) from reduced nicotinamide adenine
Simon J. Allison +6 more
openalex +3 more sources
Expert Consensus on Prevention and Treatment of COVID-19 Infection in Patients with Lung Cancer
Chinese Journal of Lung Cancer, 2023 Corona virus disease 2019 (COVID-19) infection has become a major public health issue affecting human health. The main goal of epidemic prevention and control at the current stage in China is to “protect people’s health and prevent severe cases ...
Non-small Cell Lung Cancer Expert Committee of Chinese Society of Clinical Oncology +1 more
doaj +1 more source
Journal of Oncology, 2011 The concept of cancer stem cells has generated significant interests among cancer researchers. This has led to proliferative number of publications on the subject in the recent years and eventually controversies because of conflicting data in the literature.
Lu, Bo +3 more
openaire +2 more sources
Lack of correlation of stem cell markers in breast cancer stem cells [PDF]
, 2014 BACKGROUND: Various markers are used to identify the unique sub-population of breast cancer cells with stem cell properties. Whether these markers are expressed in all breast cancers, identify the same population of cells, or equate to therapeutic ...
A M Thompson +49 more
core +7 more sources
Cold Spring Harbor Symposia on Quantitative Biology, 2011 Although the generation of a distinctive metabolic profile is a well-known aspect of cancer, the significance of these adaptations and their potential for exploitation for anticancer therapy has not been fully appreciated until recently. Many oncogenic changes known to affect intracellular signaling pathways play an active role in mediating these ...
R A, Cairns +3 more
openaire +2 more sources
Wave-Shaped Microstructure Cancer Detection Sensor in Terahertz Band: Design and Analysis
Applied Sciences, 2023 For the quick identification of diverse types of cancer/malignant cells in the human body, a new hollow-core optical waveguide based on Photonic Crystal Fiber (PCF) is proposed and numerically studied. The refractive index (RI) differs between normal and
Md Rezaul Hoque Khan +5 more
doaj +1 more source
Metabolic reprogramming of cancer-associated fibroblasts and its effect on cancer cell reprogramming
Theranostics, 2021 Cancer cells are well-known for adapting their metabolism to maintain high proliferation rates and survive in unfavorable environments with low oxygen and nutritional deficiency.
Zhenzhen Li, Chanjun Sun, Zhihai Qin
semanticscholar +1 more source
Multiscale modelling of cancer progression and treatment control : the role of intracellular heterogeneities in chemotherapy treatment [PDF]
, 2015 Cancer is a complex, multiscale process involving interactions at intracellular, intercellular and tissue scales that are in turn susceptible to microenvironmental changes.
Chaplain, Mark Andrew Joseph +1 more
core +1 more source
Journal of Innovative Optical Health Sciences, 2022 Coherent anti-Stokes Raman scattering (CARS) microscopy can resolve the chemical components and distribution of living biological systems in a label-free manner and is favored in several disciplines.
Nan Wang +9 more
doaj +1 more source
The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity
Nature, 2012 The systematic translation of cancer genomic data into knowledge of tumour biology and therapeutic possibilities remains challenging. Such efforts should be greatly aided by robust preclinical model systems that reflect the genomic diversity of human ...
J. Barretina +60 more
semanticscholar +1 more source