Results 21 to 30 of about 2,753,395 (319)

Stem cell-like cancer cells in cancer cell lines [PDF]

open access: yesInflammation and Regeneration, 2007
Both stem cells and cancer cells are thought to be capable of unlimited proliferation. Moreover, a small number of cancer cells express stem cell markers, including CD133 and ATP-binding cassette transporters, by which the cells can pump out specific fluorescence dyes, such as Hoechst33342, as well as anti-cancer drugs, suggesting that either cancer ...
openaire   +4 more sources

Cancer stem cells and addicted cancer cells [PDF]

open access: yesOncology Discovery, 2013
Advanced tumors represent a genetically heterogeneous population of cells, which compromise subpopulations with distinct properties. Research indicates that a specific population of cells within the heterogeneous population contain stem cell-like properties.
Meike E. W. Logtenberg   +1 more
openaire   +1 more source

NUMERICAL ANALYSIS OF ELECTRIC FORCE DISTRIBUTION ON TUMOR MASS IN DC ELECTRIC FIELD EXPOSURE

open access: yesSpektra: Jurnal Fisika dan Aplikasinya, 2021
Researchers have used electric fields as a new therapeutic strategy to treat cancer for the past 15 years. Tumor Treating Fields (TTFields) is an alternating electric field-based cancer therapy approved by the US FDA to treat glioblastoma multiforme (GBM)
Muhammad Arif   +3 more
doaj   +1 more source

Cancer stem cells [PDF]

open access: yesThe International Journal of Biochemistry & Cell Biology, 2012
Cancer stem cells (CSCs) are a small subpopulation of cells within tumors with capabilities of self-renewal, differentiation, and tumorigenicity when transplanted into an animal host. A number of cell surface markers such as CD44, CD24, and CD133 are often used to identify and enrich CSCs. A regulatory network consisting of microRNAs and Wnt/β-catenin,
Yu, Zuoren   +3 more
openaire   +3 more sources

‘Sex’ in the cancer cell

open access: yesOncotarget, 2014
The development of better tools for diagnosis and more accurate prognosis of cancer includes the search for biomarkers; molecules whose presence, absence or change in quantity or structure is associated with a particular tumour or prognosis/therapeutic outcome.
Inam J. Lafta   +2 more
openaire   +3 more sources

EZH2 Regulates Protein Stability via Recruiting USP7 to Mediate Neuronal Gene Expression in Cancer Cells

open access: yesFrontiers in Genetics, 2019
Misexpression of chromatin modification factors and changed epigenetic modifications play crucial roles for tumorigenesis. Our previous studies demonstrated that inhibition of epigenetic modification enzymes EZH2, LSD1, DNMTs, and HDACs caused post ...
Anhua Lei   +7 more
doaj   +1 more source

Cell proliferation and cancer.

open access: yesHistology and histopathology, 1998
The discovery that phosphorylation of selected proteins by cyclin-dependent kinases is the engine which makes the cycle run provides a new image of the control of proliferation and of its deregulation. The high conservation of this machinery in the different eukaryotic organisms emphasizes its early origin and its importance for life. It also makes the
Lopez-Saez, J.F.   +3 more
openaire   +4 more sources

Polarimetric Detection of Chemotherapy-Induced Cancer Cell Death

open access: yesApplied Sciences, 2019
Imaging polarimetry is a focus of increasing interest in diagnostic medicine because of its non-destructive nature and its potential to distinguish normal from tumor tissue. However, handling and understanding polarimetric images is not an easy task, and
Andrea Fernández-Pérez   +4 more
doaj   +1 more source

Enhanced Cellular Uptake and Pharmacokinetic Characteristics of Doxorubicin-Valine Amide Prodrug

open access: yesMolecules, 2016
In this study, we synthesized the valine (Val)-conjugated amide prodrug of doxorubicin (DOX) by the formation of amide bonds between DOX and Val. The synthesis of the DOX-Val prodrug was identified by a proton nuclear magnetic resonance (1H-NMR) assay ...
Yohan Park   +9 more
doaj   +1 more source

Diagnosis and treatment of the Cancer Tumor Cells (CTCs); Capturing and Diagnosing Kits [PDF]

open access: yesNanomedicine Research Journal, 2019
Objective(s): In the developed countries, one of the leading causes of death is cancer. Cancer cells with their unique and destructive characteristics impose high costs on communities.
Ali Alirezaie Alavijeh   +3 more
doaj   +1 more source

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