Results 21 to 30 of about 16,222,859 (319)

NUMERICAL ANALYSIS OF ELECTRIC FORCE DISTRIBUTION ON TUMOR MASS IN DC ELECTRIC FIELD EXPOSURE

Spektra: Jurnal Fisika dan Aplikasinya, 2021
Researchers have used electric fields as a new therapeutic strategy to treat cancer for the past 15 years. Tumor Treating Fields (TTFields) is an alternating electric field-based cancer therapy approved by the US FDA to treat glioblastoma multiforme (GBM)
Muhammad Arif, Warsito Purwo Taruno, Septelia Inawati Wanandi, Anto Sulaksono   +3 more
doaj   +1 more source

LOGICAL-INFORMATION MODEL OF EVALUATION THE IMPACT OF TARGETED THERAPy DRUGS ON THE BIOLOGICAL ACTIVITy OF CANCER CELLS

Тонкие химические технологии, 2017
The paper deals with laboratory preclinical studies of the impact of targeted anticancer drugs on the life of A-549 cell cultures of the cancer origin (lung carcinoma).
V. V. Burlyaev, А. Davydenko, V. F. Kornyushko, L. I. Russu, M. Mezentseva   +4 more
doaj   +1 more source

Fluid and Bubble Flow Detach Adherent Cancer Cells to Form Spheroids on a Random Positioning Machine

Cells, 2023
In preparing space and microgravity experiments, the utilization of ground-based facilities is common for initial experiments and feasibility studies. One approach to simulating microgravity conditions on Earth is to employ a random positioning machine ...
José Luis Cortés-Sánchez, Daniela Melnik, Viviann Sandt, Stefan Kahlert, Shannon Marchal, Ian R. D. Johnson, Marco Calvaruso, Christian Liemersdorf, Simon L. Wuest, Daniela Grimm, Marcus Krüger   +10 more
doaj   +1 more source

Mutational drivers of cancer cell migration and invasion

British Journal of Cancer, 2020
Genomic instability and mutations underlie the hallmarks of cancer—genetic alterations determine cancer cell fate by affecting cell proliferation, apoptosis and immune response, and increasing data show that mutations are involved in metastasis, a ...
N. M. Novikov, S. Zolotaryova, A. Gautreau, E. Denisov   +3 more
semanticscholar   +1 more source

An Efficient, Short Stimulus PANC-1 Cancer Cell Ablation and Electrothermal Therapy Driven by Hydrophobic Interactions

Pharmaceutics, 2022
Promising results in clinical studies have been demonstrated by the utilization of electrothermal agents (ETAs) in cancer therapy. However, a difficulty arises from the balance between facilitating the degradation of ETAs, and at the same time ...
Maria P. Meivita, Denise Lee, J Shamita Naikar, Shao-Xiang Go, Wey Chyi Teoh, Yaw Sing Tan, Natasa Bajalovic, Desmond K. Loke   +7 more
doaj   +1 more source

Hallmarks of Cancer: New Dimensions.

Cancer Discovery, 2022
The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast complexity of cancer phenotypes and genotypes into a provisional set of underlying principles.
D. Hanahan
semanticscholar   +1 more source

Analysis of vascular smooth muscle cell and HeLa cell migration on the microgrooved substrate (Cell type differences of the mechanical sensing for microgrooved surfaces)

Nihon Kikai Gakkai ronbunshu, 2020
Cell migration is critical in many physiological processes, including morphogenesis, wound healing, and metastasis of cancer cells, and thus elucidation of the mechanism of cell migration is quite important.
Tatsuya HANZAWA, Kazuaki NAGAYAMA
doaj   +1 more source

EZH2 Regulates Protein Stability via Recruiting USP7 to Mediate Neuronal Gene Expression in Cancer Cells

Frontiers in Genetics, 2019
Misexpression of chromatin modification factors and changed epigenetic modifications play crucial roles for tumorigenesis. Our previous studies demonstrated that inhibition of epigenetic modification enzymes EZH2, LSD1, DNMTs, and HDACs caused post ...
Anhua Lei, Lu Chen, Min Zhang, Xiaoli Yang, Liyang Xu, Ning Cao, Zan Zhang, Ying Cao   +7 more
doaj   +1 more source

Polarimetric Detection of Chemotherapy-Induced Cancer Cell Death

Applied Sciences, 2019
Imaging polarimetry is a focus of increasing interest in diagnostic medicine because of its non-destructive nature and its potential to distinguish normal from tumor tissue. However, handling and understanding polarimetric images is not an easy task, and
Andrea Fernández-Pérez, Olga Gutiérrez-Saiz, José Luis Fernández-Luna, Fernando Moreno, José María Saiz   +4 more
doaj   +1 more source

Enhanced Cellular Uptake and Pharmacokinetic Characteristics of Doxorubicin-Valine Amide Prodrug

Molecules, 2016
In this study, we synthesized the valine (Val)-conjugated amide prodrug of doxorubicin (DOX) by the formation of amide bonds between DOX and Val. The synthesis of the DOX-Val prodrug was identified by a proton nuclear magnetic resonance (1H-NMR) assay ...
Yohan Park, Ju-Hwan Park, Suryeon Park, Song Yi Lee, Kwan Hyung Cho, Dae-Duk Kim, Won-Sik Shim, In-Soo Yoon, Hyun-Jong Cho, Han-Joo Maeng   +9 more
doaj   +1 more source