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NUMERICAL ANALYSIS OF ELECTRIC FORCE DISTRIBUTION ON TUMOR MASS IN DC ELECTRIC FIELD EXPOSURE
Researchers have used electric fields as a new therapeutic strategy to treat cancer for the past 15 years. Tumor Treating Fields (TTFields) is an alternating electric field-based cancer therapy approved by the US FDA to treat glioblastoma multiforme (GBM)
Muhammad Arif +3 more
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Fluid and Bubble Flow Detach Adherent Cancer Cells to Form Spheroids on a Random Positioning Machine
In preparing space and microgravity experiments, the utilization of ground-based facilities is common for initial experiments and feasibility studies. One approach to simulating microgravity conditions on Earth is to employ a random positioning machine ...
José Luis Cortés-Sánchez +10 more
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Includes bibliography. ; Mode of access: Internet.
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Promising results in clinical studies have been demonstrated by the utilization of electrothermal agents (ETAs) in cancer therapy. However, a difficulty arises from the balance between facilitating the degradation of ETAs, and at the same time ...
Maria P. Meivita +7 more
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Misexpression of chromatin modification factors and changed epigenetic modifications play crucial roles for tumorigenesis. Our previous studies demonstrated that inhibition of epigenetic modification enzymes EZH2, LSD1, DNMTs, and HDACs caused post ...
Anhua Lei +7 more
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Stem cell-like cancer cells in cancer cell lines
Both stem cells and cancer cells are thought to be capable of unlimited proliferation. Moreover, a small number of cancer cells express stem cell markers, including CD133 and ATP-binding cassette transporters, by which the cells can pump out specific fluorescence dyes, such as Hoechst33342, as well as anti-cancer drugs, suggesting that either cancer ...
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Polarimetric Detection of Chemotherapy-Induced Cancer Cell Death
Imaging polarimetry is a focus of increasing interest in diagnostic medicine because of its non-destructive nature and its potential to distinguish normal from tumor tissue. However, handling and understanding polarimetric images is not an easy task, and
Andrea Fernández-Pérez +4 more
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Cell migration is critical in many physiological processes, including morphogenesis, wound healing, and metastasis of cancer cells, and thus elucidation of the mechanism of cell migration is quite important.
Tatsuya HANZAWA, Kazuaki NAGAYAMA
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Enhanced Cellular Uptake and Pharmacokinetic Characteristics of Doxorubicin-Valine Amide Prodrug
In this study, we synthesized the valine (Val)-conjugated amide prodrug of doxorubicin (DOX) by the formation of amide bonds between DOX and Val. The synthesis of the DOX-Val prodrug was identified by a proton nuclear magnetic resonance (1H-NMR) assay ...
Yohan Park +9 more
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ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski +59 more
wiley +1 more source

