Results 301 to 310 of about 18,416,887 (403)

Machine Learning-Driven Integration of Cancer Cell Phenotypes Predicts Cisplatin Sensitivity. [PDF]

Cancer Med
Ujiie H, Sakyo T, Oya K, Sugawara Y, Ota M, Yonezawa H, Nishiya N.   +6 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Discovery of Primaquine-Indole Carboxamides with Cancer-Cell-Selective Antiproliferative Activity. [PDF]

Molecules
Peer BH, Olugbami JO, Walunj DT, Oyelere AK.   +3 more
europepmc   +1 more source

Artesunate inhibits the growth and induces apoptosis of human gastric cancer cells by downregulating COX-2

, 2015
Ping Zhang, Hesheng Luo, Ming Li, Shiyun Tan   +3 more
openalex   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues. [PDF]

Int J Mol Med
Chen JL, Chen F, Zhang TT, Liu NF.
europepmc   +1 more source

Tumour heterogeneity and cancer cell plasticity

Nature, 2013
Corbin E. Meacham, S. Morrison
semanticscholar   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

SULF1 in Cancer Associated Fibroblasts Promotes Invasion in Head and Neck Cancer Cell Lines. [PDF]

Cancer Med
Mukherjee P, Benicky J, Panigrahi A, Ailles L, Goldman R.   +4 more
europepmc   +1 more source

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

Cell, 2010
Sreenath V. Sharma, Diana Y. Lee, Bihua Li, M. P. Quinlan, F. Takahashi, S. Maheswaran, U. McDermott, N. Azizian, L. Zou, M. Fischbach, Kwok-kin Wong, K. Brandstetter, Ben S. Wittner, Sridhar Ramaswamy, M. Classon, J. Settleman   +15 more
semanticscholar   +1 more source