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Cancer Cell Cycles

Science, 1996
Uncontrolled cell proliferation is the hallmark of cancer, and tumor cells have typically acquired damage to genes that directly regulate their cell cycles. Genetic alterations affecting p16 INK4a and cyclin D1, proteins that govern phosphorylation of the retinoblastoma protein (RB) and ...
C. Sherr
semanticscholar   +3 more sources

Abstract PR01: A cancer cell program promotes T-cell exclusion and resistance to checkpoint blockade

Cancer Research, 2020
Immune checkpoint inhibitors (ICI) produce durable responses in some melanoma patients, but many patients derive no clinical benefit, and the molecular underpinnings of such resistance remain elusive.
Livnat Jerby-Arnon   +4 more
semanticscholar   +1 more source

Renal Cell Cancer

The Cancer Journal, 2007
Metastatic renal cell cancer has traditionally been treated with interferon and interleukin-2. An improved understanding of the biology of renal cancer has engendered novel targeted therapeutic agents that have altered the natural history of this disease.
Thomas E, Hutson, Robert A, Figlin
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Germ Cell Cancers

Annals of Internal Medicine, 1981
Excerpt To the editor: The letters by Page (1) and Newcomer (2) in the May issue and the comments by other physicians in response to our article on unrecognized germ cell cancers (3) warrant a repl...
openaire   +2 more sources

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