Results 41 to 50 of about 2,753,395 (319)

Analysis of vascular smooth muscle cell and HeLa cell migration on the microgrooved substrate (Cell type differences of the mechanical sensing for microgrooved surfaces)

open access: yesNihon Kikai Gakkai ronbunshu, 2020
Cell migration is critical in many physiological processes, including morphogenesis, wound healing, and metastasis of cancer cells, and thus elucidation of the mechanism of cell migration is quite important.
Tatsuya HANZAWA, Kazuaki NAGAYAMA
doaj   +1 more source

Fluid and Bubble Flow Detach Adherent Cancer Cells to Form Spheroids on a Random Positioning Machine

open access: yesCells, 2023
In preparing space and microgravity experiments, the utilization of ground-based facilities is common for initial experiments and feasibility studies. One approach to simulating microgravity conditions on Earth is to employ a random positioning machine ...
José Luis Cortés-Sánchez   +10 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

LOGICAL-INFORMATION MODEL OF EVALUATION THE IMPACT OF TARGETED THERAPy DRUGS ON THE BIOLOGICAL ACTIVITy OF CANCER CELLS

open access: yesТонкие химические технологии, 2017
The paper deals with laboratory preclinical studies of the impact of targeted anticancer drugs on the life of A-549 cell cultures of the cancer origin (lung carcinoma).
V. V. Burlyaev   +4 more
doaj   +1 more source

BCL11A Expression in Breast Cancer

open access: yesCurrent Issues in Molecular Biology, 2023
B-cell leukemia/lymphoma 11A (BCL11A) is a transcription factor that regulates the expression of genes involved in cell division or apoptosis. A link between high BCL11A expression and a worse prognosis has been demonstrated in patients with various ...
Ewa Kątnik   +7 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

A new 99mtc labeled peptide: 99mtc β -casomorphin 6, biodistribution and imaging studies on rats [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2017
Peptide radiopharmaceuticals have an increasing significance in nuclear medicine practice. β-casomorphin is a digestive peptide with 6 amino acids (Tyr-Pro-Phe-Pro-Gly-Pro).
ERTAY T   +7 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

The cell graphs of cancer [PDF]

open access: yesBioinformatics, 2004
Abstract Summary: We report a novel, proof-of-concept, computational method that models a type of brain cancer (glioma) only by using the topological properties of its cells in the tissue image. From low-magnification (80×) tissue images of 384 × 384 pixels, we construct the graphs of the cells based on the locations of the cells within ...
S. Humayun Gultekin   +2 more
openaire   +2 more sources

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