Results 91 to 100 of about 3,490 (254)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Facteurs psychosociaux associés à l’intention de pratiquer régulièrement des activités physiques modérées chez les survivantes du cancer du sein. [PDF]
Lévesque-Gagné C, Boucher D.
europepmc +1 more source
En Belgique, toutes les femmes âgées de 50 à 69 ans sont invitées tous les 2 ans par les autorités à un examen du sein par mammographie. Le Centre Fédéral d’Expertise des Soins de Santé (KCE) avait conclu en 2010 (KCE Report 129) qu'il n'était pas opportun d’étendre ce dépistage organisé du cancer du sein aux femmes dès l’âge de 40 ans. Pour les femmes
Verleye, Leen +3 more
openaire +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
[Triple negative breast cancer: clinical, pathological and molecular characteristics]. [PDF]
Hammouda SB +5 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Stratégie d’adaptation et typologie du soutien social perçu chez les partenaires masculins de femmes atteintes d’un cancer du sein. [PDF]
Cheng T +3 more
europepmc +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source

