Results 71 to 80 of about 3,490 (254)
The Pan African Medical Journal, 2020 La chimiothérapie néoadjuvante est devenue le traitement de première intention des cancers du sein localement avancés. Elle permet d´une part, une augmentation des chances de conservation mammaire sans pour autant une majoration du risque de récidive, et
Ahmed Hajji +5 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Pan African Medical Journal, 2014 Nous rapportons un cas de pleurésie massive droite probablement métastasique accompagnée d'un lymphèdème du membre supérieur droit ayant fait suite à une mastectomie et curage ganglionnaire indiqués pour un carcinome lobulaire du sein droit, associée à ...
Lèon Kabamba Ngombe +7 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Health Research in AfricaIntroduction. Neoadjuvant chemotherapy is known to be effective in reducing the stage of locally advanced breast cancer. This study examines the response assessment of breast cancer patients to this therapy in Cameroon. Methodology.
Derliche Pamela Tonouo Wouoko +8 more
doaj +1 more source
« Une campagne efficace qui a su conscientiser les jeunes femmes au cancer du sein » : Résultats des campagnes de sensibilisation au cancer du sein auprès des jeunes Canadiennes. [PDF]
Can Oncol Nurs J, 2022 Larsen L.
europepmc +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
« Comment en parler? »: Création d’une simulation virtuelle sur les soins de santé sexuelle destinés aux survivantes du cancer du sein. [PDF]
Can Oncol Nurs J, 2023 Silva A +8 more
europepmc +1 more source