Results 51 to 60 of about 3,425,228 (311)

Kaiso phosphorylation at threonine 606 leads to its accumulation in the cytoplasm, reducing its transcriptional repression of the tumour suppressor CDH1

Molecular Oncology, 2022
It is well known that the Kaiso protein (encoded by the ZBTB33 gene) is a transcription factor, and Kaiso–P120ctn [P120 catenin (CTNND1)] interaction increases the translocation of Kaiso from the nucleus into the cytoplasm.
Wei Tian, Hongfan Yuan, Sisi Qin, Wensu Liu, Baozhen Zhang, Liankun Gu, Jing Zhou, Dajun Deng   +7 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Correlation Between TNFAIP2 Gene Polymorphism and Prediction/Prognosis for Gastric Cancer and Its Effect on TNFAIP2 Protein Expression

Frontiers in Oncology, 2020
Objective: TNFAIP2 is a novel gene induced by TNF-α and participates in inflammatory reaction and tumor angiogenesis. This study aims to understand the correlation between TNFAIP2 gene polymorphism and prediction as well as prognosis of gastric cancer ...
Fang Guo, Fang Guo, Qian Xu, Qian Xu, Qian Xu, Zhi Lv, Zhi Lv, Zhi Lv, Han-Xi Ding, Han-Xi Ding, Han-Xi Ding, Li-Ping Sun, Li-Ping Sun, Li-Ping Sun, Zhen-Dong Zheng, Yuan Yuan, Yuan Yuan, Yuan Yuan   +17 more
doaj   +1 more source

CYP3A variation, premenopausal estrone levels, and breast cancer risk.

, 2012
BACKGROUND: Epidemiological studies have provided strong evidence for a role of endogenous sex steroids in the etiology of breast cancer. Our aim was to identify common variants in genes involved in sex steroid synthesis or metabolism that are associated
Gibson, Lorna J, Jones, M, Tomlinson, IP, Ross, G, Folkerd, Elizabeth, Hillier, Stephen G, Schoemaker, M, Sawyer, Elinor, Folkerd, E, Kerin, M, Ross, Gillian, Peto, Julian, Swerdlow, A, Johnson, Nichola, Tomlinson, Ian P., Coupland, Ben, Fletcher, Olivia, Haynes, Ben, Kerin, Michael J, Williamson, Jill, Schoemaker, Minouk, Coupland, B, Simpson, Gemma, Palles, Claire, Ashworth, A, Dowsett, M, Houlston, RS, Johnson, N, Swerdlow, Anthony, Jones, Michael, Chilcott-Burns, S, Dos-Santos-Silva, Isabel, Williamson, J, Broderick, P, Zvelebil, M, Dowsett, Mitch, Walker, Kate, Fletcher, O, Houlston, Richard S, Dos Santos Silva, I, Kerin, Michael, Tomczyk, K, Walker, K, Palles, C, Zvelebil, Marketa, Gibson, Lorna J., Ashworth, Alan, Tomlinson, Ian P, Tomczyk, Katarzyna, Simpson, G, Orr, Nick; id_orcid, Orr, Nick, Orr, N, Swerdlow, Anthony J, Houlston, Richard S., Peto, J, Dos Santos Silva, Isabel, Hillier, Stephen G., Haynes, B, Hillier, SG, Sawyer, E, Broderick, Peter, Chilcott-Burns, Sarah, Gibson, LJ, Walker-Springett, Kate   +64 more
core   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Helicobacter pylori SlyD stabilizes TPT1 via hnRNPK and enhances OCT1-mediated CDX2 transcriptional activation to drive gastric intestinal metaplasia

BMC Medicine
Background Gastric intestinal metaplasia (GIM) represents an important precancerous lesion in intestinal-type gastric cancer, triggered by persistent Helicobacter pylori (H. pylori) infection.
Shuwen Zheng, Yingying Wang, Chuxuan Ni, Rui Guo, Xunan Qiu, Jijun Chen, Lu Wang, Xiaohu Sun, Moye Chen, Yunen Liu, Yuan Yuan, Yuehua Gong   +11 more
doaj   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

Arthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok, Samantha Morais, William K. Silverstein, Clare L. Atzema, Gregory Choy, Priyanka Chandratre, Ping Li, Jessica Widdifield   +7 more
wiley   +1 more source

SNP interactions of PGC with its neighbor lncRNAs enhance the susceptibility to gastric cancer/atrophic gastritis and influence the expression of involved molecules

Cancer Medicine, 2018
Multidimensional interactions of multiple factors are more important in promoting cancer initiation. Gene‐gene interactions between protein‐coding genes have been paid great attention, while rare studies refer to the interactions between encoding and ...
Zhi Lv, Liping Sun, Qian Xu, Yuehua Gong, Jingjing Jing, Nannan Dong, Chengzhong Xing, Yuan Yuan   +7 more
doaj   +1 more source

XPF expression and its relationship with the risk and prognosis of colorectal cancer

Cancer Cell International, 2021
Background XPF (xeroderma pigmentosum complementation group F) is a key factor contributing to DNA damage excision of nucleotide excision repair pathway.
Huixin Hu, Jingjing Jing, Xiaodong Lu, Yuan Yuan, Chengzhong Xing   +4 more
doaj   +1 more source

Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium.

, 2007
Association studies in large series of breast cancer patients can be used to identify single-nucleotide polymorphisms (SNP) contributing to breast cancer susceptibility.
Pharoah, Paul DP, Hogervorst, Frans BL, Dunning, Alison M, Nevanlinna, Heli A, Blomqvist, Carl,, Tommiska, Johanna, Healey, Catherine S, Pharoah, Paul D P, Tollenaar, Rob A E M, Reincke, Scarlett, Peto, Julian, Blomqvist, Carl, Van't Veer, Laura J, Johnson, Nichola, Fletcher, Olivia, Tollenaar, Rob AEM, Broeks, Annegien, Schmidt, Marjanka K, Braaf, Linde M, Hogervorst, Frans B L, Breast Cancer Association Consortium, Easton, Douglas F, Dörk, Thilo   +22 more
core   +1 more source