Results 41 to 50 of about 3,425,228 (311)

High levels of C-reactive protein are associated with an increased risk of ovarian cancer: Results from the Ovarian Cancer Cohort Consortium [PDF]

, 2019
Growing epidemiologic evidence supports chronic inflammation as a mechanism of ovarian carcinogenesis. An association between a circulating marker of inflammation, C-reactive protein (CRP), and ovarian cancer risk has been consistently observed, yet ...
Peres, Lauren C, Mallen, Adrianne R, Tjonneland, Anne, Townsend, Mary K., Magiocco, Anthony, van Gils, Carla, Merritt, Melissa A., Tworoger, Shelley S., Kvaskoff, Marina, Poole, Elizabeth M, Arslan, Alan A, Quiros, J. Ramon, Idahl, Annika, Quirós, J Ramón, Quirós, Ramón, Hartge, Patricia, Magliocco, Anthony M, Zeleniuch-Jacquotte, Anne, Trabert, Britton, Trichopoulou, Antonia, van Gils, Carla H, Fortner, Renée T, Idahl, Annika,, Poole, Elizabeth M., Tjønneland, Anne, Gram, Inger T, Allen, Naomi E., Tumino, Rosario, Allen, Naomi E, Merritt, Melissa A, Dossus, Laure, Tworoger, Shelley S, van Gils, Carla H., Wentzensen, Nicolas, Fortner, Renee T., Gram, Inger T., Townsend, Mary K, Mallen, Adrianne R., Arslan, Alan A., Visvanathan, Kala, Kaaks, Rudolf, Peres, Lauren C., Magliocco, Anthony M.   +42 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

The N6-Methyladenosine Features of mRNA and Aberrant Expression of m6A Modified Genes in Gastric Cancer and Their Potential Impact on the Risk and Prognosis

Frontiers in Genetics, 2020
Although N6-methyladenosine (m6A) mRNA methylation is known to be closely related to tumor events, its role in carcinogenesis and the development of gastric cancer (GC) is not yet clear. The aim of this study was to identify common m6A features and novel
Liang Sang, Liang Sang, Liping Sun, Liping Sun, Liping Sun, Ang Wang, Ang Wang, Ang Wang, Han Zhang, Han Zhang, Han Zhang, Yuan Yuan, Yuan Yuan, Yuan Yuan   +13 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

SLC transporters as metalloptotic gatekeepers in tumorigenesis: From molecular mechanisms to clinical potential

Pharmacological Research
Solute carrier (SLC) transporters exert a crucial effect on metalloptosis in tumors via governing the translocation of ions and amino acids across cellular and organelle membranes.
Bingchen Pan, Tan Li, Na Deng, Xin Zhang, Yangjie Peng, Yanke Li, Jingjing Jing, Liping Sun   +7 more
doaj   +1 more source

Aberrant epithelial cell interaction promotes esophageal squamous-cell carcinoma development and progression

Signal Transduction and Targeted Therapy, 2023
Epithelial-mesenchymal transition (EMT) and proliferation play important roles in epithelial cancer formation and progression, but what molecules and how they trigger EMT is largely unknown.
Liping Chen, Shihao Zhu, Tianyuan Liu, Xuan Zhao, Tao Xiang, Xiao Hu, Chen Wu, Dongxin Lin   +7 more
doaj   +1 more source

National Aboriginal and Torres Strait Islander cancer framework 2015 [PDF]

, 2015
Overview The National Aboriginal and Torres Strait Islander Cancer Framework (the Framework) provides high-level guidance and direction for the many individuals, communities, organisations and governments whose combined efforts are required to address ...
Cancer Australia
core  

Targeting the p300/CBP Axis in Lethal Prostate Cancer.

, 2021
Resistance to androgen receptor (AR) blockade in castration-resistant prostate cancer (CRPC) is associated with sustained AR signaling, including through alternative splicing of AR (AR-SV).
Crespo, M, Sharp, A, Rekowski, J, McNair, C, Swain, A, Carreira, S, de Bono, JS, Prosser, A, Onions, S, Ning, J, Raja, M, Gurel, B, West, W, Neeb, AJ, Young, B, Lane, J, Gil, VS, Paoletta, S, Worthington, J, Pereira, R, Schiewer, MJ, Yuan, W, Brooks, N, Thomson, S, Pegg, N, SU2C/PCF International Prostate Cancer Dream Team,, Taddei, D, Smyth, D, Chand, SN, Shannon, J, Knudsen, KE, Ferreira, A, Riisnaes, R, Bogdan, D, Miranda, S, Tunariu, N, Brown, R, Figueiredo, I, Harbottle, GW, Welti, J, Pal, A   +40 more
core   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Mortality Trends of Stomach Cancer in Qidong City, 1972—2016

Zhongliu Fangzhi Yanjiu, 2020
Objective To investigate the mortality trends of stomach cancer from 1972 to 2016 in Qidong, Jiangsu Province. Methods We collected and analyzed the mortality of stomach cancer in Qidong from 1972 to 2016 by gender and age from the cancer registry data ...
DING Lulu, ZHU Jian, ZHANG Yonghui, CHEN Yongsheng, WANG Jun, CHEN Jianguo   +5 more
doaj   +1 more source