Results 31 to 40 of about 287,041 (297)

Uncoding the interdependency of tumor microenvironment and macrophage polarization: insights from a continuous network approach

open access: yesFrontiers in Immunology, 2023
The balance between pro- and anti-inflammatory immune system responses is crucial to preventing complex diseases like cancer. Macrophages are essential immune cells that contribute to this balance constrained by the local signaling profile of the tumor ...
Ugo Avila-Ponce de León   +6 more
doaj   +1 more source

A new natural killer cell-specific gene signature predicting recurrence in colorectal cancer patients

open access: yesFrontiers in Immunology, 2023
The protective role of Natural Killer (NK) cell tumour immunosurveillance has long been recognised in colorectal cancer (CRC). However, as most patients show limited intra-tumoral NK cell infiltration, improving our ability to identify those with high NK
Carolyn Shembrey   +7 more
doaj   +1 more source

Neoleukin-2 enhances anti-tumour immunity downstream of peptide vaccination targeted by an anti-MHC class II VHH [PDF]

open access: yesOpen Biology, 2020
Cancer-specific mutations can lead to peptides of unique sequence presented on MHC class I to CD8 T cells. These neoantigens can be potent tumour-rejection antigens, appear to be the driving force behind responsiveness to anti-CTLA-4 and anti-PD1/L1 ...
Stephanie J. Crowley   +12 more
doaj   +1 more source

IMMUNOLOGY AND CANCER [PDF]

open access: yesAmerican Journal of Public Health and the Nations Health, 1958
This symposium is the latest in a recent series on cancer research technics and interpretations published by the Academy. Characteristically, this one includes presentations by numerous well established investigators, many of whom have published the same material elsewhere. The series as a whole, and this volume in particular, illustrates the very wide
openaire   +2 more sources

Characterization of the immune cell landscape in CRC: Clinical implications of tumour-infiltrating leukocytes in early- and late-stage CRC

open access: yesFrontiers in Immunology, 2023
IntroductionColorectal cancer (CRC) is the third leading cause of cancer-related deaths globally. Tumour-infiltrating leukocytes play an important role in cancers, including CRC.
Zainab Ali Bazzi   +6 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Cancer Immunology: From Immunosurveillance to Immunoescape

open access: yesIndonesian Journal of Cancer, 2008
Sejak lama telah diketahui bahwa sistem imun dapat mengidentifikasi dan menyingkirkan sel tumor berdasarkan ekspresi antigen tumor atau molekul yang diinduksi oleh stres pada sel.
Siti Boedina Kresno
doaj   +1 more source

Neurotransmitters: promising immune modulators in the tumor microenvironment

open access: yesFrontiers in Immunology, 2023
The tumor microenvironment (TME) is modified by its cellular or acellular components throughout the whole period of tumor development. The dynamic modulation can reprogram tumor initiation, growth, invasion, metastasis, and response to therapies.
Luxi Xiao   +5 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Natural killer cells suppress cancer metastasis by eliminating circulating cancer cells

open access: yesFrontiers in Immunology, 2023
Despite significant advances in cancer treatment, the metastatic spread of malignant cells to distant organs remains a major cause of cancer-related deaths.
Maulik Vyas   +5 more
doaj   +1 more source

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