Results 161 to 170 of about 932,314 (264)

Global breast cancer incidence, mortality, and survival among indigenous women: A systematic review and meta-analysis. [PDF]

Breast
Brewster H, Baykeda TA, Belachew SA, McCormack V, Fidler-Benaoudia M, Garvey G.   +5 more
europepmc   +1 more source

Elucidating the Mechanism behind the Enhancement of Persistent Luminescence in ZnGa2O4: Cr3+ Nanoparticles upon H2O2 Exposure

Advanced Optical Materials, EarlyView.
ABSTRACT Persistent luminescence (PersL) materials exhibit prolonged emission of light, lasting from seconds to hours after stopping the excitation. At the nanoscale, they have attracted considerable interest for applications in in vivo imaging, photodynamic therapy, and biosensing.
Celina Matuszewska, Izabel Mazon Anselmo, Mathilde Chaboud, Dimitri Mercier, Zied Ferjaoui, Cyrille Richard, Bruno Viana, Corinne Chaneac   +7 more
wiley   +1 more source

Association between alcohol consumption and breast cancer incidence and prognosis: A systematic review and meta-analysis. [PDF]

Breast
Arecco L, Cacilhas PM, Bobato Lara Gismondi C, Bruzzone M, Gentile G, Gerosa R, Blondeaux E, Agostinetto E, Dauccia C, Lobo-Martins S, Grochot R, Saini KS, Azim HA, Debiasi M, De Caluwé A, Buisseret L, Del Mastro L, Lambertini M, de Azambuja E.   +18 more
europepmc   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

Advanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun, Yihang Yuan, Qian Qiu, Kexuan Tan, Xutong Li, Haotian Li, Luyang Kang, Yuting Gu, Ziheng Zhang, Jiayu He, Jiali Li, Junjie Lin, Zihan Xie, Kexing Han, Jiabin Li, Yang Zhang, Ting Wu, Yufeng Gao   +17 more
wiley   +1 more source

Epidemiology and risk factors for ovarian cancer incidence in the USA: a multilevel analysis. [PDF]

J Glob Health
Adekanmbi V, Guo F, Wang J, Hsu CD, Hoang TN, Sokale I, Kuo YF, Uthman O, Berenson AB.   +8 more
europepmc   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source

Association of cancer incidence and randomized trial evidence for FDA approval of new cancer drugs. [PDF]

Am J Epidemiol
Schmitt AM, Herbrand A, Kasenda B, Hemkens LG.   +3 more
europepmc   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

Advanced Science, EarlyView.
Fibroblast activation protein alpha‐positive (FAPα+) macrophages, a distinct subset of multiple myeloma (MM)‐associated macrophages, drive immune evasion in MM through multi‐faceted mechanisms. FAPα physically interacts with vimentin (VIM) and triggers its phosphorylation at the S72 residue, which in turn induces PD‐L1 transcription. Additionally, FAPα
Huiyao Gu, Zhenfeng Dai, Xi Huang, Enfan Zhang, Xinyuan Dai, Haoguang Chen, Wen Cao, Jinna Zhang, Yifan Hou, Haimeng Yan, Yang Yang, Li Yang, Yi Li, Wenlong Lin, Zhen Cai, Jingsong He   +15 more
wiley   +1 more source

Association of sinonasal cancer incidence with occupation in the Nordic countries - elevated risk especially among woodworkers. [PDF]

Acta Oncol
Schindele A, Hammarstedt-Nordenvall L, Mäkitie A, Martinsen JI, Lappi-Heikkinen S, Hansen J, Lynge E, Selander J, Sivesind Mehlum I, Torfadottir JE, Wojewodzic MW, Pukkala E.   +11 more
europepmc   +1 more source