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Cancer Invasion and Metastasis
Oncology, 2005Metastasis is the transfer of malignant tumors from one organ to a distant organ. It is the most common cause of death in cancer patients. Different molecular mechanisms enable tumor cells to infiltrate the surrounding tissue, invade blood vessels and leave the blood stream at a different site.
Christian, Wittekind, Matthias, Neid
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British Medical Bulletin, 1991
The process of metastasis consists of a series of linked, sequential steps that must be completed by tumour cells if a metastasis is to develop. Although some of the steps in this process contain stochastic elements, metastasis as a whole favors the survival and growth of a few subpopulations of tumour cells that pre-exist within the heterogeneous ...
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The process of metastasis consists of a series of linked, sequential steps that must be completed by tumour cells if a metastasis is to develop. Although some of the steps in this process contain stochastic elements, metastasis as a whole favors the survival and growth of a few subpopulations of tumour cells that pre-exist within the heterogeneous ...
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The Origin of Cancer Metastasis
Canadian Bulletin of Medical History, 2005Little was known about cancer in 1829. Cancer was regarded as scirrhous, encephaloid and melanotic hard, soft and black. Deep-seated cancer was almost inevitably fatal, as was breast cancer. Surgical treatment of breast cancer was ineffective, and often fatal. Post-operative infection was very common. Radical mastectomy was 30 years in the future, and
Jean, Carr, Ian, Carr
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Seminars in Oncology Nursing, 1992
Understanding of the process by which tumor cells develop heterogeneity, invade local tissues, and spread to distant tissues is a major goal of cancer research, as it will determine whether clinicians will be able to design more effective therapies for different cancers. Although much has been learned, much remains to be learned.
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Understanding of the process by which tumor cells develop heterogeneity, invade local tissues, and spread to distant tissues is a major goal of cancer research, as it will determine whether clinicians will be able to design more effective therapies for different cancers. Although much has been learned, much remains to be learned.
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Lymphangiogenesis and cancer metastasis
Nature Reviews Cancer, 2002Lymphatic vessels are important for the spread of solid tumours, but the mechanisms that underlie lymphatic spread and the role of lymphangiogenesis (the growth of lymphatics) in tumour metastasis has been less clear. This article reviews recent experimental and clinico-pathological data indicating that growth factors that stimulate lymphangiogenesis ...
Steven A, Stacker +4 more
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Metastasis of Cancer to Cancer
JAMA, 1962MULTIPLE primary malignant neoplasms are now regarded as a common occurrence and not a medical curiosity. Despite the relative frequency of multiple malignant tumors, instances of one cancer metastasizing to another are most uncommon. The case described in this report is an example of this rare and curious association.
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Seminars in Oncology Nursing, 1998
To highlight recent research, focusing on inhibiting or blocking the metastatic process, that can be expected to be introduced to the clinical settings in the near future.Published scientific papers and review articles relating to research involving the metastatic process.An explosion of research findings is being incorporated into plausible strategies
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To highlight recent research, focusing on inhibiting or blocking the metastatic process, that can be expected to be introduced to the clinical settings in the near future.Published scientific papers and review articles relating to research involving the metastatic process.An explosion of research findings is being incorporated into plausible strategies
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Mechanisms of Cancer Metastasis
1989Metastasis, the spread of tumor cells from the primary neoplasm to distant sites and their subsequent growth, is the major cause of death of most cancer patients. Despite significant advances in early diagnosis, general patient care, surgical resection of primary neoplasms, and adjuvant systemic therapies, the majority of patients die from metastatic ...
J J, Killion, I J, Fidler
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2021
Owing to increased awareness of the importance of mammogram and advances in surgical technology, survival rate of patients with primary breast cancer has dramatically increased. Despite all these advances in breast cancer treatment, there are no currently available treatments for this disease once it metastasizes to distant organs including bones ...
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Owing to increased awareness of the importance of mammogram and advances in surgical technology, survival rate of patients with primary breast cancer has dramatically increased. Despite all these advances in breast cancer treatment, there are no currently available treatments for this disease once it metastasizes to distant organs including bones ...
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Cancer Invasion and Metastasis
The Quarterly Review of Biology, 1980Metastasis, the spread of neoplastic cells from a primary site to distant organs, is responsible for the majority of cancer deaths. Dissemination of malignant cells throughout the body and their survival to form secondary growths is a complicated process dependent on both host and tumor properties.
I R, Hart, I J, Fidler
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