Results 141 to 150 of about 970,429 (266)

Esophageal cancer mortality in China, 2008-2021: trends, disparities, and projections. [PDF]

Front Public Health
Wang M, Fang H, Tang C, Du M, Zeng R.
europepmc   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Cancer Mortality Before Age 50 Years.

JAMA Netw Open
Hutchinson JM, Ruan Y, Warkentin MT, Brenner DR.   +3 more
europepmc   +1 more source

Impact of Chile's Explicit Health Guarantees Policy on breast cancer mortality: an interrupted time series analysis (1990-2024). [PDF]

Front Oncol
Herrera MM, García-Calavaro C, Elorrieta F, Verdugo Sobral A, Toledo-Ordóñez I.   +4 more
europepmc   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Alcohol and health: an evolving relationship with a consistent risk for cancer mortality in the United States and the Americas. [PDF]

Lancet Reg Health Am
Gallardo-Vera F, Beltran-Ontiveros SA, Rochin-Teran JL, Diaz D.   +3 more
europepmc   +1 more source

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

Advanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang, Qiubo Chen, Shihai Lan, Liang Zhu, Shuaiyu Liu, Yan Xia, Yalu Zhang, Hanhui Yao, Yongman Liu, Shangquan Wu, Qingchuan Zhang   +10 more
wiley   +1 more source

Breast cancer mortality by age and race and/or ethnicity across counties in the United States, 2000-2019. [PDF]

J Natl Cancer Inst
Jayasekera J, Hooshmand S, Strassle PD, Schneider J, Mensah GA, Mensah L, George S, Kelly YO, Baumann MM, Li Z, McHugh TA, Celone M, Sylte DO, La Motte-Kerr W, Bhangdia K, Force LM, Murray CJL, Alvarez CS, Choi K, Mokdad AH, Dwyer-Lindgren L, Pérez-Stable EJ.   +21 more
europepmc   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Population ageing and gastric cancer mortality burden in China, 2008-2021: a nationwide analysis with projections to 2036. [PDF]

Front Public Health
Fang H, Zhang Y, Ning Y, Mu J.
europepmc   +1 more source