Results 61 to 70 of about 1,686,195 (359)

Cancer risk and mortality among firefighters: a meta-analytic review

Frontiers in Oncology, 2023
BackgroundFirefighting is a hazardous occupation that is associated with an increased risk of select cancers. The number of studies has grown in recent years allowing for a synthesis of findings.MethodsFollowing PRISMA guidelines, multiple electronic ...
David J. Lee, David J. Lee, Soyeon Ahn, Laura A. McClure, Laura A. McClure, Alberto J. Caban-Martinez, Alberto J. Caban-Martinez, Alberto J. Caban-Martinez, Erin N. Kobetz, Erin N. Kobetz, Erin N. Kobetz, Henna Ukani, Devina J. Boga, Diana Hernandez, Paulo S. Pinheiro, Paulo S. Pinheiro   +15 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Lung cancer epidemiology in North Sardinia, Italy [PDF]

, 2013
Background The aim of this study was to analyze and describe the epidemiological characteristics and trends of lung cancer in North Sardinia, Italy, in the period 1992–2010.
Attene, Federico, Budroni, Mario, Cesaraccio, Rosaria, Cossu, Antonio, Paliogiannis, Panagiotis, Palmieri, Giuseppe, Tanda, Francesco, Trignano, Mario   +7 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Systemic immune inflammatory index and mortality in chronic kidney disease

Frontiers in Endocrinology
BackgroundChronic kidney disease (CKD) is common and linked to higher mortality rates, but its relationship with the systemic immunoinflammatory index (SII) remains unclear, highlighting the need for further research.MethodsThe SII is calculated by ...
Yanshuang Ma, Yanshuang Ma, Yang Yu, Zhongdan Jia, Hushan Wang, Mingli Sun   +5 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Impact of non-high-density lipoprotein cholesterol in mortality and cardiovascular events among middle-aged Russian men: 40 years ago and now

Рациональная фармакотерапия в кардиологии
Aim. To evaluate the non-high density lipoprotein cholesterol (non-HDL-C) predictive ability in relation to cardiovascular events, all-cause and cause-specific mortality and among middle-aged Russian men now and 40- years ago.Material and methods.
S. A. Shalnova, A. E Imaeva, Yu. A Balanova, V. A Kutsenko, A. V Kapustina, V. A Metelskaya, N. A Imaeva, B. M Nazarov, O. E Ivlev, E. B Yarovaya, O. M Drapkina   +10 more
doaj   +1 more source

Urinary Lead Concentration Is an Independent Predictor of Cancer Mortality in the U.S. General Population

Frontiers in Oncology, 2018
Lead is a ubiquitous pollutant that constitutes an environmental hazard worldwide. Although lead has been known as a carcinogenic factor in animal models, its role in human carcinogenesis is still a topic of debate with limited epidemiological evidence ...
Sen Li, Sen Li, Jiaxin Wang, Biao Zhang, Yuan Liu, Tao Lu, Yuanyuan Shi, Guangliang Shan, Ling Dong   +8 more
doaj   +1 more source

Systemic inflammation predicts all-cause mortality: a Glasgow Inflammation Outcome Study [PDF]

, 2015
Introduction: Markers of the systemic inflammatory response, including C-reactive protein and albumin (combined to form the modified Glasgow Prognostic Score), as well as neutrophil, lymphocyte and platelet counts have been shown to be prognostic of ...
Fletcher, Colin D., Horgan, Paul G., McMillan, Donald C., Morrison, David S., Proctor, Michael, Talwar, Dinesh   +5 more
core   +2 more sources

Cancer Mortality in Italy, 1993

Tumori Journal, 1997
Background Data and statistics are presented on cancer death certification for 1993 in Italy, updating previous publications covering the period 1955–1992. Methods Data for 1993 subdivided into 30 cancer sites are presented in 8 tables, including age-and sex-specific absolute and percentage frequencies of cancer deaths, and crude, age-specific and age ...
A. Decarli, C. La Vecchia
openaire   +2 more sources