Results 131 to 140 of about 6,321,039 (371)
CDC Guideline for Prescribing Opioids for Chronic Pain--United States, 2016.
Journal of the American Medical Association (JAMA), 2016 IMPORTANCE Primary care clinicians find managing chronic pain challenging. Evidence of long-term efficacy of opioids for chronic pain is limited. Opioid use is associated with serious risks, including opioid use disorder and overdose.
D. Dowell, Tamara M. Haegerich, R. Chou
semanticscholar +1 more source
Cancer Control, 2000 Controlling pain in cancer patients is often inadequate. A recent multicenter study of patients with metastatic disease who were experiencing pain reported that 36% still had pain severe enough to compromise their daily function.The author draws on his experiences as well as those of others to review general guidelines and provide specific ...
openaire +2 more sources
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.NeoCast is a next‐generation, solvent‐free, non‐adhesive liquid embolic designed for indications where deep occlusion is desired (e.g., tumors and chronic subdural hematoma). This novel agent offers ideal embolic properties: injectability, controllability, excellent visibility, and biocompatibility.
Quynh P. Pham +16 more
wiley +1 more source
Rocuronium-sugammadex use for electroconvulsive therapy in a hemodialysis patient: a case report
JA Clinical Reports, 2016 Background Recently, rocuronium with subsequent use of sugammadex was proposed for electroconvulsive therapy (ECT) as an alternative to succinylcholine.
Shigeaki Kurita +5 more
doaj +1 more source
Pain Research and Management, 2017 Cancer is an increasing public health burden for Ethiopia. Pain is among the most common symptoms in patients with cancer. Hence, we aimed to assess cancer pain prevalence, cancer pain interference, and adequacy of cancer pain treatment in the oncology ...
H. Tegegn, E. Gebreyohannes
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Ovarian cancer's high recurrence and therapy resistance demand new strategies. A high‐throughput drug screening pipeline using 3D spheroids, which showed poor concordance with 2D models, identified rapamycin as a promising candidate. In combination with cisplatin, rapamycin demonstrated significant in vitro and in vivo efficacy, highlighting the ...
Nazanin Karimnia +9 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie +5 more
wiley +1 more source
40. Use of Hydrate of Chloral for the Relief of Pain in Cancer [PDF]
, 1870 F. B. Clarke
openalex +1 more source
Advanced Healthcare Materials, EarlyView.A new dual‐layer hydrogel barrier for preventing postoperative abdominal adhesions is developed. The inner layer, consisting of polyethyleneimine (PEI) and thioctic acid (TA), enhanced adhesion to moist tissues. The outer layer combines zwitterionic, thermoresponsive hyaluronic acid with anti‐inflammatory epigallocatechin gallate (EGCG) and forms a ...
Mena Asha Krishnan +6 more
wiley +1 more source