Results 201 to 210 of about 6,321,039 (371)

Lovo‐cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB‐206 study

American Journal of Hematology, Volume 98, Issue 1, Page 11-22, January 2023., 2023
Treatment process evolution. *The target TNC for BMH was ≥6 × 108/kg per patient. The Group B1 patient received lovo‐cel produced using both the original and refined manufacturing process, and the Group B2 patient received lovo‐cel produced using only the refined manufacturing process.
Julie Kanter, Alexis A. Thompson, Francis J. Pierciey Jr, Matthew Hsieh, Naoya Uchida, Philippe Leboulch, Manfred Schmidt, Melissa Bonner, Ruiting Guo, Alex Miller, Jean‐Antoine Ribeil, David Davidson, Mohammed Asmal, Mark C. Walters, John F. Tisdale   +14 more
wiley   +1 more source

Neurolytic Celiac Plexus Block for Pancreatic Cancer Pain

, 1987
David L. Brown, C. Kevin Bulley, Edward L. Quiel   +2 more
openalex   +1 more source

A Four‐drug pain regimen for head and neck cancers [PDF]

, 1994
Edward N. Carrol, Edward J. Fine, Robert L. Ruff, David W. Stepnick   +3 more
openalex   +1 more source

M6A Modified miR‐31‐5p Suppresses M1 Macrophage Polarization and Autoimmune Dry Eye by Targeting P2RX7

Advanced Science, EarlyView.
The upregulation of FTO in autoimmune dry eye suppresses the recognition of pri‐miR‐31 by DGCR8, thereby inhibiting the maturation of miR‐31‐5p and reducing its inhibitory effect on the target gene P2RX7. The activation of P2RX7 subsequently triggers the p38 MAPK signaling pathway and increases the level of M1‐related genes, thus exacerbating the ...
Lu Zhao, Xuejia Li, Min Gao, Lin Liu, Binyun Ma, Xun Liu, Jiachen Zhang, Ruoxuan Liu, Bei Du, Ruihua Wei, Hong Nian   +10 more
wiley   +1 more source

Cutaneous T‐cell lymphomas: 2023 update on diagnosis, risk‐stratification, and management

American Journal of Hematology, Volume 98, Issue 1, Page 193-209, January 2023., 2023
Abstract Disease Overview Cutaneous T‐cell lymphomas are a heterogenous group of T‐cell neoplasms involving the skin, the majority of which may be classified as Mycosis Fungoides (MF) or Sézary Syndrome (SS). Diagnosis The diagnosis of MF or SS requires the integration of clinical and histopathologic data.
Alexandra C. Hristov, Trilokraj Tejasvi, Ryan A. Wilcox   +2 more
wiley   +1 more source

Interpleural analgesia through a DuPen catheter for lung cancer pain [PDF]

, 1992
J L Aguilar, A. Montes, Daniel Samper, G Roca, Fernando Vidal   +4 more
openalex   +1 more source

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

Advanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie, Chen Chen, Fei Wu, Yiman Peng, Jing Su, Yang Zhao, Hongjie Huang, Zhong Alan Li, Yin Pei, Wencui Li, Yi He, Tianchen Xue, Chenxi Cao, Sui Peng, Xin Zhang, Weidong Song   +15 more
wiley   +1 more source

An overview of pain and symptom management in advanced cancer

, 1987
Frank Brescia
openalex   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Epidural vs intrathecal morphine-bupivacaine: Assessment of consecutive treatment in advanced cancer pain

, 1988
P. Nitzescu, L. Appelgren, L.E. Linder, Magdalena Sjöberg, E Hultman, I Curelaru   +5 more
openalex   +1 more source