Results 41 to 50 of about 6,321,039 (371)

Cancer pain physiology [PDF]

open access: yesBritish Journal of Pain, 2014
Mechanisms of inflammatory and neuropathic pains have been elucidated and translated to patient care by the use of animal models of these pain states. Cancer pain has lagged behind since early animal models of cancer-induced bone pain were based on the systemic injection of carcinoma cells.
Falk, Sarah   +2 more
openaire   +4 more sources

Ultrasound-guided continuous erector spinae plane block vs continuous thoracic epidural analgesia for the management of acute and chronic postthoracotomy pain: a randomized, controlled,double-blind trial

open access: yesPAIN Reports, 2023
. Introduction:. Postthoracotomy pain (PTP) is a severe pain complicating thoracic surgeries and its good management decreases the risk of PTP syndrome (PTPS). Objectives:.
Ehab Hanafy Shaker   +8 more
doaj   +1 more source

Efficacy and harms of long‐term opioid therapy in chronic non‐cancer pain: Systematic review and meta‐analysis of open‐label extension trials with a study duration ≥26 weeks

open access: yesEuropean Journal of Pain, 2019
This updated systematic review evaluated the efficacy, acceptability and safety of long‐term opioid therapy (LTOT) for chronic non‐cancer pain (CNCP).
P. Bialas   +3 more
semanticscholar   +1 more source

Hydromorphone for cancer pain [PDF]

open access: yesCochrane Database of Systematic Reviews, 2016
Cancer pain is an important and distressing symptom that tends to increase in frequency and intensity as the cancer advances. For people with advanced cancer, the prevalence of pain can be as high as 90%. It has been estimated that 30% to 50% of people with cancer categorise their pain as moderate to severe, with between 75% and 90% of people with ...
Wei Hou   +6 more
openaire   +4 more sources

Safety and efficacy of dexmedetomidine vs ketamine vs midazolam combined with propofol in gastrointestinal endoscopy for cancer patients: A randomized double-blinded trial

open access: yesEgyptian Journal of Anaesthesia, 2023
Background A wide range of drugs are used for sedation in gastrointestinal (GI) endoscopy procedures, including midazolam, dexmedetomidine, and ketamine. Therefore, this study aimed to compare the effects of these drugs in combination with propofol among
Nahla N Shehab   +2 more
doaj   +1 more source

Intelligent Sight and Sound: A Chronic Cancer Pain Dataset [PDF]

open access: yes2021, Thirty-fifth Conference on Neural Information Processing Systems Datasets and Benchmarks Track, 2022
Cancer patients experience high rates of chronic pain throughout the treatment process. Assessing pain for this patient population is a vital component of psychological and functional well-being, as it can cause a rapid deterioration of quality of life.
arxiv  

A Novel Model of Cancer-Induced Peripheral Neuropathy and the Role of TRPA1 in Pain Transduction [PDF]

open access: yesPain Research and Management, Volume 2017, Article ID 3517207, 2018
Background. Models of cancer-induced neuropathy are designed by injecting cancer cells near the peripheral nerves. The interference of tissue-resident immune cells does not allow a direct contact with nerve fibres which affects the tumor microenvironment and the invasion process. Methods.
arxiv   +1 more source

Neuropathic cancer pain: prevalence, pathophysiology, and management

open access: yesThe Korean Journal of Internal Medicine, 2018
Neuropathic cancer pain (NCP) is caused by nerve damage attributable to the cancer per se, and/or treatments including chemotherapy, radiotherapy, and surgery; the prevalence is reported to be as high as 40%.
S. Yoon, Jeeyoung Oh
semanticscholar   +1 more source

The Neurobiology of Cancer Pain [PDF]

open access: yesThe Neuroscientist, 2014
The global burden of cancer pain is enormous and opioids, despite their side effects, remain the primary therapeutic approach. The cause of cancer pain is unknown. Mechanisms driving cancer pain differ from those mechanisms responsible for inflammatory and neuropathic pain.
openaire   +6 more sources

Xenon treatment after severe traumatic brain injury improves locomotor outcome, reduces acute neuronal loss and enhances early beneficial neuroinflammation: a randomized, blinded, controlled animal study

open access: yesCritical Care, 2020
Background Traumatic brain injury (TBI) is a major cause of morbidity and mortality, but there are no clinically proven treatments that specifically target neuronal loss and secondary injury development following TBI.
Rita Campos-Pires   +8 more
doaj   +1 more source

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