Results 61 to 70 of about 1,118,006 (364)

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Effects of propofol-based total intravenous anesthesia on recurrence and overall survival in patients after modified radical mastectomy: a retrospective study [PDF]

Korean Journal of Anesthesiology, 2016
BackgroundThe optimal combination of anesthetic agent and technique may have an influence on long-term outcomes in cancer surgery. In vitro and in vivo studies suggest that propofol independently reduces migration of cancer cells and metastasis.
Ji Heui Lee, Seok Hee Kang, Yunkwang Kim, Hyun Ah Kim, Bong Seog Kim   +4 more
doaj   +1 more source

The Flavonoid Hesperidin Methyl Chalcone Targets Cytokines and Oxidative Stress to Reduce Diclofenac-Induced Acute Renal Injury: Contribution of the Nrf2 Redox-Sensitive Pathway

Antioxidants, 2022
Hesperidin is derived from citrus fruits among other plants. Hesperidin was methylated to increase its solubility, generating hesperidin methyl chalcone (HMC), an emerging flavonoid that possess anti-inflammatory and antioxidant properties.
Allan J. C. Bussmann, Tiago H. Zaninelli, Telma Saraiva-Santos, Victor Fattori, Carla F. S. Guazelli, Mariana M. Bertozzi, Ketlem C. Andrade, Camila R. Ferraz, Doumit Camilios-Neto, Antônio M. B. Casella, Rubia Casagrande, Sergio M. Borghi, Waldiceu A. Verri   +12 more
doaj   +1 more source

Pain Level Detection From Facial Image Captured by Smartphone [PDF]

, 2016
Accurate symptom of cancer patient in regular basis is highly concern to the medical service provider for clinical decision making such as adjustment of medication.
Ahamed, Sheikh Iqbal, Ahsan, Golam Mushih Tanimul, Hasan, Md Kamrul, Love, Rechard, Salim, Reza   +4 more
core   +1 more source

How can we help family carers manage pain medicines for patients with advanced cancer? A systematic review of intervention studies [PDF]

, 2016
Background: Family carers play a significant role in managing pain and associated medicines for people with advanced cancer. Research indicates that carers often feel inadequately prepared for the tasks involved, which may impact on carer and patient ...
Edwards, Deborah, Hopkinson, Jane, Hughes, James, Latter, Susan, Lowson, Elizabeth, Richardson, Alison   +5 more
core   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

[Ru(bpy)2(NO)SO3](PF6), a Nitric Oxide Donating Ruthenium Complex, Reduces Gout Arthritis in Mice

Frontiers in Pharmacology, 2019
Monosodium urate crystals (MSU) deposition induces articular inflammation known as gout. This disease is characterized by intense articular inflammation and pain by mechanisms involving the activation of the transcription factor NFκB and inflammasome ...
Ana C. Rossaneis, Daniela T. Longhi-Balbinot, Mariana M. Bertozzi, Victor Fattori, Carina Z. Segato-Vendrameto, Stephanie Badaro-Garcia, Tiago H. Zaninelli, Larissa Staurengo-Ferrari, Sergio M. Borghi, Thacyana T. Carvalho, Allan J. C. Bussmann, Florêncio S. Gouveia, Luiz G. F. Lopes, Rubia Casagrande, Waldiceu A. Verri   +14 more
doaj   +1 more source

Comparative randomized study of continuous serratus anterior plane block versus continuous paravertebral block in post-mastectomy pain

Ain Shams Journal of Anesthesiology, 2020
Background Many analgesic methods have been used to control post-mastectomy pain. Both thoracic paravertebral and serratus anterior blocks are recent regional techniques with promising results.
Essam Mahran, Suzan Adlan, Nelly Alieldeen   +2 more
doaj   +1 more source

Resolvin D5 (RvD5) Reduces Renal Damage Caused by LPS Endotoxemia in Female Mice

Molecules, 2022
In self-revolving gram-negative Escherichia coli infection, Resolvin D5 (RvD5) was found to enhance bacteria phagocytosis and reduce the production of inflammatory mediators, contributing to the resolution of infection. LPS (lipopolysaccharide) is a gram-
Renato D. R. Cardoso, Sandmary D. Chambo, Tiago H. Zaninelli, Beatriz H. S. Bianchini, Matheus Deroco Veloso da Silva, Mariana M. Bertozzi, Telma Saraiva-Santos, Anelise Franciosi, Geovana Martelossi-Cebinelli, Pamela E. Garcia-Miguel, Sergio M. Borghi, Rubia Casagrande, Waldiceu A. Verri   +12 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source