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This paper explores the role of patient advocacy in fostering patient-centered care (PCC), empowerment, and equitable access to healthcare in the Middle East and Africa (MEA) region.
Sawsan Al-Madhi +12 more
doaj +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Cancer Trends: Primary Liver Cancer
During 2012-2014, a little over half (58%) of all primary liver cancers were histologically confirmed, 37% were diagnosed radiologically only via x-ray, MRI/CT scan etc. and 5% did not have a method of diagnosis specified.
National Cancer Registry Ireland (NCRI)
core
Diagnosing cancer in an emergency: Patterns of emergency presentation of cancer in Ireland 2002–2015 [PDF]
Emergency presentation with cancer can result from lack of awareness of symptoms in patients and is generally associated with more advanced stage, limited treatment options and poorer survival outcomes.
National Cancer Registry Ireland (NCRI) +1 more
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Laddering Through Pedigrees: Family History of Malignancies in Primary Breast Cancer Patients [PDF]
A family history (FH) of breast cancer (BC) is a long recognized risk factor for developing the disease. Also, there have been some reports of links between an FH and some other malignancies (mostly uterus, ovary, and prostate cancers), and an ...
جعفری مجرد, الهام +4 more
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Prehabilitation in cancer patients
Prehabilitation in oncology is a strategy aimed at improving the patient's functional, nutritional, and psychological status prior to cancer treatment, especially surgery. Growing evidence supports its effectiveness in improving postoperative outcomes and tolerance to treatments such as chemotherapy and radiotherapy. This review outlines the conceptual
Ovidio, Hernando-Requejo +1 more
openaire +2 more sources

