Results 81 to 90 of about 1,454,075 (309)
Global burden of lung cancer attributable to occupational asbestos exposure: 1990 to 2021
Environmental HealthBackground Asbestos is a well-established occupational carcinogen, with strong evidence linking its exposure to lung cancer. Despite increasing awareness of its health risks, asbestos continues to be used in many countries.
Qiulin Huang +6 more
doaj +1 more source
Oral Cancer Awareness and its Determinants among a Selected Malaysian Population [PDF]
, 2013 Objective: To assess oral cancer awareness, its associated factors and related sources of information among a selected group of Malaysians. Methods: A cross-sectional survey was conducted on all Malaysian ethnic groups aged >= 15 years old at eight ...
Doss, J. G. +4 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
BMC Cancer, 2018 Background We evaluated the incidence and spectrum of pathogenic and likely pathogenic variants of cancer susceptibility genes in BRCA1/2 mutation-negative Korean patients with a high risk for hereditary breast cancer using a comprehensive multigene ...
Ji Soo Park +7 more
doaj +1 more source
Long noncoding RNAs in prostate cancer: overview and clinical implications. [PDF]
, 2016 Prostate cancer is the second most common cause of cancer mortality among men in the United States. While many prostate cancers are indolent, an important subset of patients experiences disease recurrence after conventional therapy and progresses to ...
Feng, Felix Y, Malik, Bhavna
core +3 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Association between mukbang-watching (eating broadcasts) and depression in Korean adults
BMC PsychiatryBackground Mukbang is an online content genre where hosts eat large amounts of food while interacting with viewers. While earlier studies have suggested an association between mukbang viewing to obesity and disordered eating, its association with ...
Hyein Jung +3 more
doaj +1 more source
Breast Cancer Screening in Racialized Women: Implications for Health Equity [PDF]
, 2014 Inequalities across the breast cancer continuum due to racialization have significantly affected women's access to screening programs, diagnosis, treatment and survival.
Aziza Mahamoud
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source