Results 41 to 50 of about 26,447,258 (401)

Disulfide-Modified Mesoporous Silica Nanoparticles for Biomedical Applications

Crystals, 2023
Mesoporous silica nanoparticles (MSNs) are highly porous carriers used in drug and gene delivery research for biomedical applications due to their high surface area, narrow particle size distribution, and low toxicity.
Melissa Venedicto, Jake Carrier, Ha Na, Chen-Yu Chang, Daniela R. Radu, Cheng-Yu Lai   +5 more
doaj   +1 more source

Cancer models in preclinical research: A chronicle review of advancement in effective cancer research

Animal Models and Experimental Medicine, 2021
Cancer is a major stress for public well‐being and is the most dreadful disease. The models used in the discovery of cancer treatment are continuously changing and extending toward advanced preclinical studies. Cancer models are either naturally existing
Humna Sajjad, Saiqa Imtiaz, Tayyaba Noor, Y. Siddiqui, Anila Sajjad, M. Zia   +5 more
semanticscholar   +1 more source

p21 in Cancer Research [PDF]

Cancers, 2019
p21 functions as a cell cycle inhibitor and anti-proliferative effector in normal cells, and is dysregulated in some cancers. Earlier observations on p21 knockout models emphasized the role of this protein in cell cycle arrest under the p53 transcription factor activity.
Bahar Shamloo, Sinem Usluer
openaire   +3 more sources

Lab-on-Chip Platform for Culturing and Dynamic Evaluation of Cells Development

Micromachines, 2020
This paper presents a full-featured microfluidic platform ensuring long-term culturing and behavioral analysis of the radically different biological micro-objects.
Agnieszka Podwin, Danylo Lizanets, Dawid Przystupski, Wojciech Kubicki, Patrycja Śniadek, Julita Kulbacka, Artur Wymysłowski, Rafał Walczak, Jan A. Dziuban   +8 more
doaj   +1 more source

RNA sequencing: new technologies and applications in cancer research

Journal of Hematology & Oncology, 2020
Over the past few decades, RNA sequencing has significantly progressed, becoming a paramount approach for transcriptome profiling. The revolution from bulk RNA sequencing to single-molecular, single-cell and spatial transcriptome approaches has enabled ...
Mingye Hong, Shuang Tao, Ling Zhang, Li-Ting Diao, Xuanmei Huang, Shaohui Huang, Shu-juan Xie, Zhen-Dong Xiao, Hua Zhang   +8 more
semanticscholar   +1 more source

Tumorbank@uza: A Collection of Tissue, Fluid Samples and Associated Data of Oncology Patients for the Use in Translational Research

Open Journal of Bioresources, 2018
Tumorbank@UZA is an academic hospital integrated biobank that collects tissue, blood and urine samples from oncology patients. We work according to a quality management system and have established SOPs for all work procedures in the biobank.
Sofie Goethals, Annemieke De Wilde, Katrien Lesage, Elke Smits, Patrick Pauwels, Marc Peeters   +5 more
doaj   +1 more source

Establishing guidelines to harmonize tumor mutational burden (TMB): in silico assessment of variation in TMB quantification across diagnostic platforms: phase I of the Friends of Cancer Research TMB Harmonization Project

Journal for ImmunoTherapy of Cancer, 2020
Background Tumor mutational burden (TMB), defined as the number of somatic mutations per megabase of interrogated genomic sequence, demonstrates predictive biomarker potential for the identification of patients with cancer most likely to respond to ...
Diana M Merino, L. McShane, D. Fabrizio, V. Funari, Shu-Jen Chen, J. White, P. Wenz, J. Baden, J. Barrett, R. Chaudhary, Li Chen, W. Chen, J. Cheng, D. Cyanam, J. Dickey, Vikas Gupta, M. Hellmann, E. Helman, Yali Li, Joerg Maas, Arnaud Papin, R. Patidar, K. Quinn, N. Rizvi, H. Tae, Christine Ward, Mingchao Xie, A. Zehir, Chen Zhao, M. Dietel, A. Stenzinger, M. Stewart, J. Allen   +32 more
semanticscholar   +1 more source

Scaffold-based 3D cell culture models in cancer research

Journal of Biomedical Sciences
Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer research, offering significant advantages over traditional two-dimensional (2D) cell culture systems.
Waad H. Abuwatfa, W. Pitt, G. Husseini
semanticscholar   +1 more source

THE CANCER PROBLEM AND CANCER RESEARCH. [PDF]

The Lancet, 1905
n ...
Beard, J., Shaw-Mackenzie, JohnA
openaire   +2 more sources

TOX3 mutations in breast cancer [PDF]

, 2013
TOX3 maps to 16q12, a region commonly lost in breast cancers and recently implicated in the risk of developing breast cancer. However, not much is known of the role of TOX3 itself in breast cancer biology.
Caldas, Carlos, Chin, Suet-Feung, Jones, James Owain, Leaford, Donna, Maia, Ana Teresa, Ponder, Bruce A. J., Wong-Taylor, Li-An   +6 more
core   +3 more sources