Results 41 to 50 of about 3,844,733 (310)
Senescent stromal cells promote cancer resistance through SIRT1 loss-potentiated overproduction of small extracellular vesicles [PDF]
, 2020 Cellular senescence is a potent tumor-suppressive program that prevents neoplastic events. Paradoxically, senescent cells develop an inflammatory secretome, termed the senescence-associated secretory phenotype (SASP), which is implicated in age-related ...
Jiang, Jing +13 more
core +1 more source
Lab-on-Chip Platform for Culturing and Dynamic Evaluation of Cells Development
Micromachines, 2020 This paper presents a full-featured microfluidic platform ensuring long-term culturing and behavioral analysis of the radically different biological micro-objects.
Agnieszka Podwin +8 more
doaj +1 more source
Engaging European society at the forefront of cancer research and care
Molecular Oncology, 2023 European cancer research stakeholders met in October 2022 in Heidelberg, Germany, at the 5th Gago conference on European Cancer Policy, to discuss the current cancer research and cancer care policy landscape in Europe.
Michael Baumann +29 more
doaj +1 more source
Translational cancer research – a coherent cancer research continuum [PDF]
Molecular Oncology, 2019 The main components of the cancer research continuum are basic/preclinical research, early and late clinical research and, after the adoption of an innovation by the healthcare or health organisations, outcomes research. Translational cancer research, defined as a coherent cancer research continuum, is mandatory to address the increasing burden of ...
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille +9 more
wiley +1 more source
Dicer elicits paclitaxel chemosensitization and suppresses cancer stemness in breast cancer by repressing AXL [PDF]
, 2016 [[abstract]]Paclitaxel is a standard-of-care chemotherapy for breast cancer, despite the increasing recognition of its poor effectiveness in the treatment of patients with advanced disease.
Chang, TY;Chen, HA;Chiu, CF;Chang, YW;Kuo, TC;Tseng, PC;Wang, W;Hung, MC;Su, JL
core +1 more source
Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer. [PDF]
, 2022 The retinoblastoma tumor suppressor (RB) is a critical regulator of E2F-dependent transcription, controlling a multitude of protumorigenic networks including but not limited to cell-cycle control.
Mandigo, AC +13 more
core +1 more source
Mission‐oriented translational cancer research – health economics
Molecular Oncology, 2019 Health economics is an integrated aspect of all phases of mission‐oriented translational cancer research and should be considered an intrinsic component of any study aimed at improving outcomes for patients and intervention costs. Information about value
Bengt Jönsson, Richard Sullivan
doaj +1 more source
Unleashing the Power of OpenAI in Shaping the Future of Cancer Research
BioMed Target Journal, 2023 Artificial intelligence (AI) is rapidly changing cancer research and treatment development. OpenAI, a pioneer in AI research, is at the vanguard of this revolution.
Ramyar M. Abdullah +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger +7 more
wiley +1 more source