Results 71 to 80 of about 52,240,321 (193)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Zhongguo aizheng zazhiLeptomeningeal metastasis from breast cancer is one of the severe complications of advanced breast cancer, characterized by complex and variable clinical manifestations, rapid disease progression, and an extremely poor prognosis.
Clinical Cancer Research Evaluation Committee of Chinese Medical Education Association +1 more
doaj
Oncology research in the kingdom of Bahrain: a four-decade bibliometric evolution
Frontiers in OncologyIntroductionBahrain reports the highest age-standardized cancer incidence among Gulf Cooperation Council (GCC) countries, but its oncology research output has not been comprehensively mapped. We profiled four decades of Bahrain-linked cancer publications
Randah R. Hamadeh +4 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Cancer Research UK Cancer Awareness Measures, September 2023
copyright UK Data Service and data collection copyright owner.The Cancer Awareness Measure (CAM) was developed in 2007-8 to address the absence of a validated measure of general public awareness of cancer (Stubbings, S., Robb, K., Waller, J., Ramirez, A.,
Cancer Research UK
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Zhongguo aizheng zazhiBreast cancer is the most common malignancy among women in China, with approximately 70% of cases being hormone receptor (HR)-positive. Although current therapeutic strategies have significantly improved patient outcomes, endocrine resistance remains a ...
Clinical Cancer Research Evaluation Committee of Chinese Medical Education Association +2 more
doaj
Molecular OncologyGenetic alterations in key oncogenes have been frequently identified in lung adenocarcinoma (LUAD), including genes encoding epidermal growth factor receptor (EGFR), Kirsten rat sarcoma viral oncogene homolog (KRAS), and anaplastic lymphoma kinase (ALK).
Fanni Bugyi +12 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2016 [[abstract]]Paclitaxel is a standard-of-care chemotherapy for breast cancer, despite the increasing recognition of its poor effectiveness in the treatment of patients with advanced disease.
Chang, TY;Chen, HA;Chiu, CF;Chang, YW;Kuo, TC;Tseng, PC;Wang, W;Hung, MC;Su, JL
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