Results 91 to 100 of about 2,125,565 (269)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş +5 morewiley +1 more sourceFruit and vegetable consumption and risk of epithelial ovarian cancer: The European prospective investigation into cancer and nutrition
, 2005 OBJECTIVE: The association between consumption of fruit and vegetables and risk of ovarian cancer is still unclear from a prospective point of view. METHODS: Female participants (n = 325,640) of the European Prospective Investigation into Cancer and ...Gram, IT, Allen, N., Büchner, Frederike L., González, Carlos A., Kaaks, Rudolph, Key, Timothy, Peeters, Petra H.M., Tormo, Maria J., Peeters, P.H.M., Palli, D, Tjønneland, A, Larranaga, N., Riboli, E., Berglund, G, Galasso, R., Clavel-Chapelon, Françoise, Jenab, M, Pasanisi, P., Palli, Domenico, Key, TJ, Boutron-Ruault, M.C., Jenab, Mazda, Key, Timothy J.A., Trichopoulos, D, Vineis, P., Bueno-de-Mesquita, H. Bas, Quirós, JR, Overvad, K., Schulz, M, Olsen, A, Gram, Inger T., Hallmans, G, Boutron-Ruault, Marie Christine, Linseisen, Jakob, Tormo, M.J., Lund University., Buchner, F.L., Tjonneland, A., Tetsche, Mette, Skeie, Guri, Büchner, FL, Lahmann, P.H., Jenab, M., Ardanaz, E., Lukanova, Annekatrin, Olsen, A., Pasanisi, Patrizia, Lahmann, PH, Boeing, H, Bueno de Mesquita, H.B., Ardanaz, E, Larrañaga, Nerea, Berglund, Göran, van Gils, van, Schulz, M., Garcia, CM, Lukanova, A., Berglund, G., Kalapothaki, V., Quirós, José R., Quiros, J.R., Linseisen, J, Schulz, Mandy, Wirfält, Elisabet,, Martinez Garcia, C., Skeie, G, Clavel-Chapelon, F, Tormo, MJ, Tjønneland, Anne, Lukanova, A, Allen, N, Trichopoulou, A., Trichopoulou, A, Skeie, G., Key, TJA, van Gils, CH, Allen, Naomi, Bingham, Sheila, Vineis, Paolo, Hoffmann, K, Lundin, E, Hallmans, Göran, Berglund, Göran,, Norat, T., González, CA, Peeters, PH, Hoffmann, Kurt, Kalapothaki, V, Lundin, E., Touillaud, M., Pasanisi, P, Tetsche, M., Lahmann, Petra H., Tumino, R., Lund, Eiliv, Trichopoulou, Antonia, Trichopoulos, D., Martínez Garcia, Carmen, Riboli, E, Riboli, Elio, Linseisen, J., Touillaud, Marina, Tumino, Rosario, Hoffmann, K., Chang-Claude, J, Wirfält, Elisabet, van Gils, Carla H., Norat, T, Ardanaz, Eva, et al., Olsen, Anja, Lund, E., Touillaud, M, Larrañaga, N, Key, T.J., Wirfalt, E., Lundin, Eva, Wirfält, E, Kalapothaki, Victoria, Bingham, S, Chang-Claude, J., Galasso, R, Boeing, H.H., Chang-Claude, Jenny, van Gils, C.H., Trichopoulos, Dimitrios, Galasso, Rocco, Gonzalez, C.A., Norat, Teresa, Hallmans, G., Martínez Garcia, C, Overvad, Kim, Gram, I.T., Boutron-Ruault, MC, Overvad, K, Clavel-Chapelon, F., Palli, D., Tetsche, M, Lund, E, Peeters, PHM, Tjonneland, A, Tumino, R, Vineis, P, Kaaks, R, Kaaks, R., Boeing, Heiner, Bueno-de-Mesquita, HB +146 morecore +1 more sourceAlcohol and Cancer: Mechanisms and Therapies
Biomolecules, 2017 Several scientific and clinical studies have shown an association between chronic alcohol consumption and the occurrence of cancer in humans. The mechanism for alcohol-induced carcinogenesis has not been fully understood, although plausible events ...Anuradha Ratna, Pranoti Mandrekardoaj +1 more sourceCase-Case Genome-Wide Analyses Identify Subtype-Informative Variants That Confer Risk for Breast Cancer.
Breast cancer includes several subtypes with distinct characteristic biological, pathologic, and clinical features. Elucidating subtype-specific genetic etiology could provide insights into the heterogeneity of breast cancer to facilitate the development Knight, JA, John, EM, Hu, JJ, Buas, MF, Reiner, AS, Cai, Q, Pal, T, Jia, G, Derkach, A, Chen, Y, Ambrosone, CB, Olopade, OI, Chen, J, Press, MF, Shu, X, Gu, J, Ping, J, Sandler, DP, Zheng, W, Haiman, CA, Offit, K, Wang, X, Nemesure, B, Troester, MA, Palmer, JR, Guo, X, Nathanson, KL, Garcia-Closas, M, Shu, X-O, Woods, M, Yang, Y, Watt, GP, Sanderson, M, Liang, X, Ambs, S, Concannon, P, Verma, SP, Huo, D, Bernstein, JL, Oh, JH, Lynch, CF, Olshan, AF, Long, J, Li, CI, Sun, X, Mellemkjær, L +45 morecore +1 more sourceBreast cancers arising in high mammographic density tissue harbor tumor-promoting immune profiles
npj Breast CancerEpidemiological studies have shown that high mammographic density (HMD) is a strong risk factor for breast cancer (BC) and is associated with poor prognosis.Dane Cheasley, Meagan Ruppert, Lisa Devereux, Madawa W. Jayawardana, Qihong Zhao, Carolyn Nickson, Melrine Pereira, David J. Byrne, Stephen B. Fox, Ian G. Campbell, Kara L. Britt +10 moredoaj +1 more sourceCircular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk +17 morewiley +1 more sourceFine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk. [PDF]
, 2014 Common variants in the hepatocyte nuclear factor 1 homeobox B (HNF1B) gene are associated with the risk of Type II diabetes and multiple cancers. Evidence to date indicates that cancer risk may be mediated via genetic or epigenetic effects on HNF1B gene ...Olson, J.E., Spurdle, A.B., Schrauwen, S., Doerk, T., Hall, P, CHIBCHA Consortium, Werner, HM, Webb, PM, Tzortzatos, G., Long, J., Liu, J., Hein, A, Amant, F., Tomlinson, I., Ruebner, M, Attia, J., McEvoy, M., Shu, X.-O., Rojas-Martinez, A, Martin, N.G., Zheng, W., Proietto, T, Dieffenbach, AK, Rudolph, A, Meindl, A., Swerdlow, A.J., Dunning, A.M., Santos, E., Dowdy, SC, Ferguson, K, Batra, J., Tyrer, J.P., De Polanco, MM, Lambrechts, D., Pollock, P, Salvesen, H.B., Hopper, JL, Coenegrachts, L., Fasching, P.A., Runnebaum, I., Michailidou, K., Ekici, A.B., Wang, Q, Batra, J, Johnson, N., Henders, AK, Canc, ANE, Marme, F., Ferguson, K., Montgomery, G.W., Ahmed, S, Spurdle, AB, Otton, G., Dunning, AM, Czene, K, Burwinkel, B, Easton, DF, Liu, J, Sans, M., Otton, G, Healey, C.S., Teoman, A., Ruebner, M., Borresen-Dale, A.-L., Bolla, MK, French, JD, Werner, H.M.J., Carracedo, A., RENDOCAS, Ahmed, S., Painter, JN, Trovik, J., Cheng, T, Fridley, BL, Shu, X-O., Orr, N., Borresen-Dale, A-L., Marme, F, Painter, J.N., Winterhoff, B, Teoman, A, O'Mara, T.A., Australian Ovarian Cancer Study (AOCS), Lindblom, A., Consortium, CHIBCHA, Mints, M., Scott, R.J., Southey, M.C., Canc, N.S.E., Martin, NG, Gorman, M., Bolla, M.K., Shu, XO, Johnson, N, Chang-Claude, J, Amant, F, Bruinsma, F, Cunningham, JM, Olson, JE, Henders, A.K., Moisse, M, Castellvi-Bel, S., Pollock, P., Li, J, Hopper, J.L., Dennis, J, Cox, A, Ashton, K., Hall, P., Hillemanns, P., Weber, R.P., Depreeuw, J, Magdalena Echeverry De Polanco, M., Dork, T., Ekici, AB, Dürst, M, Brauch, H, Pharoah, P.D.P., Moisse, M., Network, GENICA, Dennis, J., Peto, J, Trovik, J, McEvoy, M, Edwards, SL, Lose, F.A., Xiang, Y-B., Goode, E.L., Lambrechts, D, Howarth, K, Teixeira, M.R., Kaufmann, S., Renner, SP, De Polanco, MME, Weber, RP, O'Mara, TA, Mints, M, Cunningham, J.M., AOCS, Jones, A., Gorman, M, Santos, E, Beckmann, M.W., Tomlinson, I, Fridley, B.L., Castellvi-Bel, S, Giles, GG, Dowdy, S.C., Schrauwen, S, Montgomery, GW, Martin, L., Xiang, Y.-B., Teixeira, MR, Tham, E, Wang, Q., Thompson, DJ, Proietto, T., Coenegrachts, L, GENICA Network, Cheng, T., Lindblom, A, Nyholt, D.R., Brenner, H., Attia, J, Li, J., Carvajal-Carmona, L., Long, J, Tzortzatos, G, Swerdlow, AJ, Pollock, P.M., Couch, FJ, Fasching, PA, Southey, MC, Meindl, A, Hillman, KM, Brauch, H., Moya, L., Burwinkel, B., Bruinsma, F., Howarth, K., French, J.D., Hodgson, S., Orr, N, Lose, FA, Scott, RJ, Børresen-Dale, AL, Czene, K., Pharoah, PD, Renner, S.P., Holliday, E., Hodgson, S, National Study of Endometrial Cancer Genetics Group (NSECG), Beckmann, MW, Kaufmann, S, Chen, Z., Martin, L, Walpole, C., Tyrer, JP, Shah, M., Healey, CS, Walpole, C.M., Brenner, H, Winterhoff, B., Hillman, K.M., Carvajal-Carmona, L, Kristensen, VN, Durst, M., Sans, M, Ashton, K, Duerst, M., Rojas-Martinez, A., Moya, L, Giles, G.G., Walpole, C, Jones, A, Xiang, YB, Cox, A., Tham, E., Runnebaum, I, Salvesen, HB, Werner, HMJ, Holliday, E, Peto, J., Couch, F.J., Carracedo, A, Hillemanns, P, Chen, Z, Depreeuw, J., Webb, P.M., Rudolph, A., Michailidou, K, Njolstad, T.S., Chang-Claude, J., Easton, D.F., Australian National Endometrial Cancer Study Group (ANECS), Thompson, D.J., Shah, M, Zheng, W, Edwards, S.L., Dieffenbach, A.K., Njolstad, TS, De Polanco, M.M.E., Dörk, T, Kristensen, V.N., Nyholt, DR, Goode, EL, Hein, A. +246 morecore +1 more source
