Results 111 to 120 of about 2,125,565 (269)
Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang +12 morewiley +1 more sourceFine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression [PDF]
, 2013 Associations between single nucleotide polymorphisms (SNPs) at 5p15 and multiple cancer types have been reported. We have previously shown evidence for a strong association between prostate cancer (PrCa) risk and rs2242652 at 5p15, intronic in the ...Hayes, R B, Schumacher, Fredrick, Severi, G., Berndt, S.I., Key, Timothy, Berndt SI, Spurdle A, Dicks, E, Ingles, SA, Le Marchand L, Muir, K; id_orcid, Ingles, S., Albanes, D, Canzian, F., Cybulski, C., Easton DF, Riboli, E., Halim, Silvia, Govindasami, K, Muir, Ken, Conroy, Don, Thobodeau, S.N, Eeles RA, Vogel, W., Muir, K, Hamdy, Freddie C., Leongamornlert, DA, Bacot F, Guy, Michelle, Wilkinson, R.A., Dunning, A.M., Albanes, D., Benlloch, S, Russell R, Clements, Judith A., Key TJ, Al Olama AA, Pharoah P, Morgan, A., Tymrakiewicz, M., Travis RC, Lee, A., Benlloch, S., Hamdy, FC, Stanford, JL, Batra, J., Ingles, Sue A., John, EM, Berndt, Sonja I., Giles, Graham G., Hunter, D.J., Donovan, JL, Wilkinson RA, Thibodeau, Stephen N., Kibel AS, Dadaev T, Luccarini C, Khaw KT, Kraft, P., Gapstur, Susan, Vogel W, Park, Jong Y., Stanford, Janet L., Bojesen SE, Kaneva, Radka, Ostrander, Elaine A., Wilkinson, Rosemary A., Haiman, Christopher A., Batra, J, Ostrander, E A, John EM, Key, Tim J., Schleutker J, Haiman, C.A., Lubinski, Jan, Thibodeau, S N, Lindstrom, S, Schleutker, J, Tessier DC, Key, T J, Maier, C., Le Marchand, Loic, Dunning, AM, John, E.M., Easton, DF, Campa, D., Russel, R, Henderson BE, Ostrander, EA, Spurdle, A., Khaw, KT, Easton, D F, Kaneva, R., Henderson, B E, Hamdy FC, Muir, K.R., Vincent D, Russell, R, Donovan, Jenny, Kraft, P, Khaw, K-T, Clements JA, Guy M, Dennis, Joe, Marchand, LL, Gapstur, S., Sawyer, E.J., Neal, David E., Leongamornlert, D.A., John, Esther M., Albanes, Demetrius, Stanford, J.L., Jugurnauth-Little, Sarah, Kibel, AS, Schaid, D., Cybulski, C, Ingles SA, Govindasami, Koveela, Lubinski, J, Wiklund, F., Donovan JL, Riboli, E, Donovan, J L, Hayes RB, Gronberg, H, Hamdy, F.C., Batra, Jyotsna, Signorello, L.B., Ross Adams H, Campa, Daniele, Gapstur, S, Travis, Ruth, Neal, D E, Wilkinson, RA, Signorello, Lisa B., Key, T.J., Pharoah, P, Muir, Kenneth, Dennis, J, Ghoussaini, M., Lindstrom, S., Neal, DE, Hunter DJ, Dadaev, T, Bojesen, Stig E., Canzian, F, John, E M, Vincent, Daniel, Eeles, RA, Ostrander, E.A., Ross-Adams, Helen, Park JY, Park, JY, Saunders, EJ, Hamdy, F C, Dadaev, T., Baynes, C., Signorello, L B, Wilkinson, R A, Muir K, Bojesen, S E, Haiman CA, Saunders, E J, Baynes, Caroline, Dennis, J., Andriole G, Ross-Adams, H., Henderson, BE, Teixeira, M R, Baynes, C, Dennis J, Gronberg, Henrik, Sawyer EJ, Vincent, D., Campa, D, Saunders, E., Pharoah, Paul, Tessier, DC, Teixeira, M.R., Hunter, David J., Hunter, D J, Chanock, Stephen, Tymrakiewicz, M, Maier C, COGS CRUK GWAS ELLIPSE Initiative, Kaneva R, Travis, R C, Signorello, LB, Kote-Jarai, Z., Cybulski, Cezary, Baynes C, Donovan, J.L., Weischer, Maren, Park, J Y, Leongamornlert DA, Ostrander EA, Lubinski J, Luccarini, Craig, Dicks E, Cannon-Albright, L., Cannon-Albright, Lisa, Marchand, L L, Travis, Ruth C., Giles, GG, Ross-Adams, H, Pharoah, P., Giles, Graham, Kibel, Adam S., Kaneva, R, Neal DE, Khaw, Kay-Tee, Bacot, François, Haiman, CA, Teixeira, MR, Teixeira, Manuel R., Al Olama, AA, Giles, G G, Halim S, Key, TJ, Andriole, Gerald, Tessier, Daniel C., Benlloch, Sara, Conroy D, Hunter, DJ, Schumacher, F, Stanford JL, Schleutker, Johanna, Donovan, Jenny L., Brenner, H., Wiklund, F, Kraft, Peter, Brenner H, Al Olama, A A, Kaaks, Rudolf, Canzian F, Luccarini, C, Andriole, G, Clements, J., Canzian, Federico, Kaaks R, Conroy, D.K., Severi G, Park, J.Y., Severi, G, Signorello LB, Schleutker, J., Tymrakiewicz M, Cannon-Albright, L, Jugurnauth Little S, Bojesen, SE, Saunders EJ, Tessier, D.C., Riboli E, Spurdle, A, Bacot, F, Schaid D, Neal, D.E., Severi, Gianluca, Vincent, D, Henderson, Brian E., Vogel, Walther, Russel, Roslin, Ingles, S A, Albanes D, Khaw, K T, Batra J, Dunning AM, Gapstur S, Tessier, D C, Travis, RC, Morgan, Angela, PRACTICAL Consortium, Cybulski C, Weischer, M, Weischer M, Haiman, C A, Schaid, Dan, Conroy, D, Cannon Albright L, Bacot, F., Luccarini, C., Kote-Jarai, Zsofia, Sawyer, Emma J., Chanock, S, Maier, C, Teixeira MR, Chanock, S., UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology, Gronberg, H., Vogel, W, Schumacher F, Kote-Jarai, Z, Brenner, H, Saunders, Edward J., Weischer, M., Govindasami, K., Wiklund F, Le Marchand, L., Kote Jarai Z, Benlloch S, Maier, Christiane, Guy, M, Easton, Douglas F., Amin Ali, A.L., Travis, R.C., Guy, M., Dadaev, Tokhir, Henderson, B.E., Tymrakiewicz, Malgorzata, Wiklund, Fredrik, Hayes, R.B., Govindasami K, Thibodeau, SN, Kibel, A S, UK ProtecT Study Collaborators, Clements, JA, Giles, G.G., Clements, J A, Thibodeau SN, Lubinski, J., Al Olama, Ali Amin, Kraft P, Russel, R., Jugurn-Little, S, Eeles, R A, Dunning, Alison M., Schaid, D, Stanford, J L, Berndt, SI, Chanock S, Eeles, R.A., Le Marchand, L, Leongamornlert, D A, Sawyer, E J, Andriole, G., Dicks, E., Easton, D.F., Giles GG, Pashayan, N., Hayes, Richard B., Lindstrom, Sara, Hamdy, Freddie, Kibel, A.S, Spurdle, Amanda, Morgan, A, Sawyer, EJ, Leongamornlert, Daniel A., Dicks, Ed, Morgan A, Brenner, Hermann, Gronberg H, Schumacher, F.R., Lindstrom S, Jugurnath-Little, S., Halim, S., Hayes, RB, Kaaks, R, Dunning, A M, Jugurnauth-Little, S, Eeles, Rosalind A., Halim, S, Berndt, S I +361 morecore +1 more sourceInterrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne +61 morewiley +1 more sourceIdentification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants.
, 2019 Genome-wide association study-identified prostate cancer risk variants explain only a relatively small fraction of its familial relative risk, and the genes responsible for many of these identified associations remain unknown.Cavazos, TB, Wu, L, Penney, KL, Guo, X, Cai, Q, Shu, X-O, Bauer, JA, Eeles, RA, Wang, J, Pasaniuc, B, Emami, NC, Kote-Jarai, Z, Witte, JS, PRACTICAL, CRUK, BPC3, CAPS, PEGASUS Consortia,, Lu, Y, Long, J, Zheng, W, Freedman, ML, Haiman, CA +18 morecore +1 more sourceKeratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer +13 morewiley +1 more sourceCommon breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2
, 2011 The associations of the 12 SNPs with risk for BRCA1 and BRCA2 carriers differ by ER-positive or ER-negative breast cancer status. The apparent differences in SNP associations between BRCA1 and BRCA2 carriers, and non-carriers, may be explicable by ...Donaldson, A., Danièle Muller, Mark H Greene, L Mai, Phuong,, SWE-BRCA, Madeleine MA Tilanus Linthorst, Engel, C., Pankratz, Vernon, Murray, A, Muy-Kheng Tea, Barrowdale, D., Paul DP Pharoah, Wachenfeldt, v.A., Lynch, Henry, Maria A Caligo, Network, OCG, Wachenfeldt, A. (Anna) von, Anne Marie Gerdes, Boutry-Kryza, Nadia, Barkardottir, Rosa B, F Easton, Douglas,, Varon-Mateeva, Raymonda, Investigators, K, Tilanus-Linthorst, Madeleine M. A., Ozcelik, Hilmi, Pascal Pujol, Breast Canc Family Registry, Kast, K, Kets, C.M. (Marleen), Raymonda Varon Mateeva, Wachenfeldt, V., Martine Dumont, Ejlertsen, B. (Bent), Meindl, A., K Godwin, Andrew, Gschwantler-Kaulich, D. (Daphne), Viel, Alessandra, Meijers-Heijboer, Hanne E.J., Heli Nevanlinna, Patricia A. Ganz, de la Hoya, Miguel, Andrew K. Godwin, Couch, F.J. (Fergus), Skytte, Anne-Bine, Paolo Peterlongo, Janavicius, Ramunas,, Bonanni, Bernardo, Ana Osorio, John L Hopper, Viel, A., Y Karlan, Beth,, Arnold, N, Soller, M., Mai, P.L. (Phuong), Caldes, Trinidad,, Hopper, JL, Olopade, Olufunmilayo, Ruehl, Ina, Gross, J. (Jenny), Eason, J., Chung, Wendy K., Kirsten B. Moysich, A. C. Breast Cancer Family Registry Antoniou, Wachenfeldt, VA, Arver, Brita, A Ganz, Patricia, Pujol, P, Brita Arver, Niederacher, D, Hansen, Thomas V.O., Miguel de la Hoya, Radice, Paolo,, Mark Sherman, Rookus, Matti, Sherman, Mark, Berthet, Pascaline, Benitez, Javier,, Verheus, Martijn, François Cornelis, Godino, J, Neuhausen, S.L. (Susan), Douglas F. Easton, Mulligan, A.M., S Pankratz, Vernon, Osorio, A, Hardouin, A, Os, Theo V., Antonis C. Antoniou, Rebbeck, Timothy R, Esther M John, Mazoyer, S, Aittomäki, K., Evans, D.G. (Gareth), Blanco, I, Rosa B. Barkardottir, Benítez, J. (Javier), Lee, A, Papi, Laura, Muller, D, Gómez García, EB, Kirsten B Moysich, Deissler, Helmut,, van Os, Theo, Gordon Glendon, Lebrun, Marine, Michel Longy, Spurdle, Amanda B, Antoniou, Antonis, Frances P. O'Malley, Pujol, Pascal,, Greene, Mark H., Ganz, Patricia A, Cattaneo, E., Iván Muñoz-Repeto, Berthet, P., Daphne Gschwantler-Kaulich, Gross, Jenny, Henry T. Lynch, J Louise Jones, Susan L Neuhausen, Buys, Saundra M, Mortemousque, Isabelle, Coupier, Isabelle,, Pertesi, M, Fricker, J-P, Ignacio Blanco, Hansen, T.V., Donaldson, A, Peissel, Bernard,, Fredericksen, Z, Henriksson, K, Eeles, R., van Der Luijt, Rob, Niederacher, Dieter,, Hopper, J.L., Godwin, AK, Fassy-Colcombet, M. (Marion), Tilanus-Linthorst, Madeleine M.A., Schäfer, D., Eason, J. (Jacqueline), Peock, Susan,, Cornelis, F, Peterlongo, Paolo, Evans, D. Gareth; id_orcid, Glendon, Gordon,, Pharoah, P.D.P., Dieter Schäfer, Varon-Mateeva, R, Olopade, O.I., Kruse, Torben A, Ganz, P.A. (Patricia), Ros Eeles, Chung, W., Terry, Mary, Beattie, M., Leone, Melanie,, Montagna, M., Javier Godino, Robson, Mark,, Durán, M., Kruse, Torben A., Gregory, H, Noralane M. Lindor, Gadzicki, D., Lindor, Noralane M, Pankratz, Vernon S, Davidson, R., Fricker, Jean-Pierre, Soucy, Penny, Susan J. Ramus, Raymonda Varon-Mateeva, Berthet, P. (Pascaline), Jensen, Uffe, Birk, Tilanus-Linthorst, M.M.A. (Madeleine), Simard, J. (Jacques), Miron, Alexander F., Manoukian, S. (Siranoush), Julian Barwell, Kruse, T.A., Godino, J. (Javier), van Os, Theo,, Os, Theo van, Robson, Mark, Sue Healey, Frances P O'Malley, Gerdes, Anne-Marie, GEMO Study Collaborators, Madeleine MA Tilanus-Linthorst, Bonanni, Bernardo,, Singer, Christian, Caux-Moncoutier, V. (Virginie), Engel, Christoph, Tognazzo, Silvia,, Kauff, N. (Noah), Pertesi, Maroulio,, Torben A. Kruse, Adlard, Julian,, Aittomäki, K. (Kristiina), Sakr, R. (Rita), Ramunas Janavicius, Buys, SM, Ottini, Laura,, Schäfer, Dieter, Marie Stenmark-Askmalm, Soller, Maria,, Janavicius, R, Gevensleben, H, Heidrun Gevensleben, Rookus, M, Hansen, Thomas V., Godwin, Andrew K, Christian Sutter, Meindl, A, DAndrea, Emma,, Karlan, B.Y., Muy Kheng Tea, Sevenet, N., Mai, Phuong L, Toland, Amanda E, Dieter Niederacher, Caux-Moncoutier, V, Benítez, J., Wijnen, J., Muller, Danièle, Hamann, U. (Ute), Ottini, Laura, Moysich, Kirsten B., Gross, J, Madeleine M. A. Tilanus Linthorst, Iván Muñoz Repeto, E Side, Lucy, Susan J Ramus, Henry T Lynch, Arver, B. (Brita Wasteson), Muller, D.W. (Danièle), Isaacs, Claudine, Barrowdale, Daniel,, Esther M. John, Peterlongo, P, Southey, Melissa C., Fredericksen, Z., Hansen, Thomas vO., Olopade, Olufunmilayo I, Bhatia, Jasmine, Wijnen, J, Heinritz, W., Mai, PL, Ozcelik, H, Rosa B Barkardottir, Manoukian, S., Antoniou, A.C. (Antonis), Gerdes, Anne-Marie,, Peock, S. (Susan), Thomassen, M. (Mads), Gómez García, Encarna B., Domchek, SM, Daniel Barrowdale, Henriksson, Karin, Kientz, Caroline,, Caux-Moncoutier, Virginie, Gaudet, M., Kets, C Marleen,, Sevenet, Nicolas,, Kauff, N, Adlard, J.W. (Julian), Adlard, J, Lee, A. (Andrew), Mortemousque, Isabelle,, Easton, Douglas F., Melissa C Southey, Ruehl, I. (Ina), Léoné, Mélanie, Skytte, A.-B. (Anne-Bine), Emma McCann, Lebrun, M., Bernard Peissel, Andrulis, I.L. (Irene), Lazaro, C, Caligo, MA, Hanne EJ Meijers-Heijboer, Os, Theo v, Wang, X.S., Caux-Moncoutier, V., Houghton, C., Heikinen, T. (Tuomas), Jacqueline Eason, Deissler, H. (Helmut), Schmutzler, RK, Anne Bine Skytte, Gadzicki, D. (Dorothea), Saundra M. Buys, Donaldson, Alan,, Gerdes, A-M. (Anne-Marie), O'Malley, Frances, F Miron, Alexander,, Maria A. Caligo, Weitzel, JN, Seynaeve, C.M. (Caroline), Sutter, C., Pharoah, Paul D. P., Ozcelik, H. (Hilmi), Anne-Marie Gerdes, Helmut Deissler, Gaudet, Mia,, Finn C Nielsen, F Miron, Alexander, Garcia, E.B.G., Rookus, M., Eccles, Diana,, Coupier, I., Fassy-Colcombet, Marion, Caligo, Maria A, Toland, Amanda E., Penny Soucy, L Nathanson, Katherine, McCann, E., Mulligan, Anna Marie, Mads Thomassen, Spurdle, Amanda, Meindl, Alfons,, C Southey, Melissa,, Domchek, S.M., Deissler, H., Mazoyer, S., Eeles, Ros, McGuffog, L. (Lesley), Tea, Muy-Kheng, Preisler-Adams, Sabine,, Gadzicki, D, Fergus J Couch, Hansen, TV, Frost, D., Terry, MB, Marcel R Nelen, Vernon S Pankratz, Marion Fassy Colcombet, Os, T. van, Neuhausen, Susan, Hopper, John L., Hansen, TVO, B Barkardottir, Rosa,, Hamann, U, Conxi Lazaro, Schoenbuchner, Ines, Imyanitov, E., Antoniou, AC, Rosemarie Davidson, Isaacs, C., Wachenfeldt, von A, Soller, M, Pujol, Pascal, Davidson, R, Donaldson, Alan, Eason, Jacqueline,, Adlard, Julian, Offit, K, Sherman, M.E. (Mark), Donaldson, A. (Alan), Frost, D, Daly, Mary B, Schaefer, Dieter, Cook, J., Wang, XS, Wang, Xianshu, Ottini, L, Caligo, Maria, Peock, Susan, Hansen, Thomas v, Karlan, BY, Moysich, Kirsten B, Rhiem, K, Mazoyer, S. (Sylvie), E. M. John, Yan, M. (Max), Benitez, Javier, Boutry-Kryza, N, Muñoz-Repeto, I., Papi, L., Ontario Canc Genetics Network, Ding, Yuan,, Lee, A., Nielsen, FC, Luijt, R.B. (Rob) van der, Mary B. Daly, John, EM, Preisler-Adams, S. (Sabine), Barkardottir, R.B. (Rosa), Wachenfeldt, von Anna, Mulligan, AM, Sakr, R., Chung, W. (Wendy), Caldes, T. (Trinidad), Kientz, C, Nathanson, K.L. (Katherine), Izatt, Louise, Savarese, A., Pankratz, V.S. (Shane), Os, Theo, Rita K. Schmutzler, Wang, X, Muller, D., Sutter, C, Gadzicki, Dorothea,, Kientz, Caroline, Manoukian, Siranoush,, Ganz, P.A., Lalloo, F., Heikkinen, T., Alan Donaldson, Wang, Xianshu,, C Marleen Kets, Evans, D G, Mortemousque, I. (Isabelle), Houghton, Catherine,, Ontario Cancer Genetics Network, Adlard, J., Loris Bernard, Bhatia, Jasmine,, Os, Theo, Van, Hamann, Ute, Yan, Max, Cornelis, F. (Franco̧is), Fassy-Colcombet, M., E Tomlinson, Gail, Singer, Christian F, Kruse, T.A. (Torben), Norbert Arnold, Kets, C Marleen, Easton, Douglas, Jean Pierre Fricker, Godwin, A.K. (Andrew), McGuffog, L., Blanco, I., Peissel, Bernard, Stenmark-Askmalm, M., Schaefer, Dieter,, Sevenet, N. (Nicolas), Sevenet, N, Miron, A. (Alexander), P OMalley, Frances,, Radice, Paolo, Frost, Debra, Ganz, PA, van der Luijt, RB, Jeffrey N Weitzel, Fricker, J.P., Arnold, Norbert, L Andrulis, Irene,, Rebbeck, T, Kast, Karin, Pharoah, Paul DP, Ramus, S.J., Barkardottir, Rosa, Caldes, T., Daly, Mary B., Gregory, Helen,, Sakr, R, Murray, A., Miron, AF, Ruehl, Ina,, Sinilnikova, OM, Maroulio Pertesi, Jones, J Louise, Meijers-Heijboer, Hanne E, Fricker, Jean-Pierre,, Chun Ding, Yuan, Side, L.E., Boutry-Kryza, Nadia,, Ramus, Susan J, C. Marleen Kets, Noah Kauff, Ozcelik, H., Caroline Seynaeve, Trinidad Caldes, Daphne Gschwantler Kaulich, Soucy, Penny,, Stoppa-Lyonnet, D., Peterlongo, P. (Paolo), Munoz-Repeto, Ivan,, Rookus, M.A. (Matti), A Ganz, Patricia,, Soller, Maria, Side, Lucy E, Dorkins, H, Daly, M.B. (Mary), Henriksson, Karin,, D P Pharoah, Paul,, Glendon, Gordon, A Kruse, Torben,, van Os, T., Wijnen, Juul, McCann, Emma, H Greene, Mark, Karlsson, Per,, Karin Kast, Fredericksen, Z. (Zachary), Huw Dorkins, Caldes, T, Hoya, M. (Miguel) de La, Paul D. P. Pharoah, Alexander F. Miron, Cattaneo, Elisa, Stenmark-Askmalm, M, D P Pharoah, Paul, Gail E. Tomlinson, Susan M Domchek, Stoppa-Lyonnet, D, Tilanus-Linthorst, Madeleine M A, Peterlongo, P., Lázaro, C. (Conxi), Garcia, Encarna B. Gomez, Barwell, Julian, John, Esther, Greene, Mark H, Gevensleben, H. (Heidrun), Stoppa-Lyonnet, D. (Dominique), Bent Ejlertsen, Montagna, M, Beattie, Mary, Ejlertsen, B, Caux-Moncoutier, Virginie,, Viel, A. (Alessandra), Anneliese Fink-Retter, Peterlongo, Paolo,, Nelen, Marcel R, Encarna B Gómez García, Mulligan, Anna, Marie, Jackie Cook, Dumont, M., Neuhausen, Susan L, Terry, Mary, Beth, Karlsson, P., Lee, Andrew Roger, Barbara Wappenschmidt, Family Registry, Breast Cancer, Meindl, Alfons, Terry, Mary,, Neuhausen, S.L., L Neuhausen, Susan, Lazaro, Conxi, Ejlertsen, Bent,, Evgeny Imyanitov, Anna Marie Mulligan, Terry, Mary B., Soucy, P., Eason, J, Martijn Verheus, Tomlinson, Gail E, Arver, Brita,, Gevensleben, Heidrun, Heikkinen, Tuomas, Toland, Amanda, Isabelle Mortemousque, Tilanus-Linthorst, MMA, Dorkins, Huw, Healey, S, McCann, Emma,, Aittomäki, Kristiina, Heinritz, W. (Wolfram), Couch, Fergus, I Olopade, Olufunmilayo, Tognazzo, S., Tomlinson, G.E., EMBRACE, Dorothea Gadzicki, Hardouin, Agnès, Preisler-Adams, S., Toland, A.E., Greene, M.H., Karlan, Beth, Nevanlinna, H., Coupier, Isabelle, Hoya, M. de la, Nathanson, Katherine L, von Wachenfeldt, Anna, Pasini, B, Sutter, Christian,, A Caligo, Maria,, McGuffog, Lesley, Lazaro, C (Conxi), Fink-Retter, A. (Anneliese), Hilmi Ozcelik, Collaborators, GEMOS, Pharoah, Paul D P, Lee, Andrew, Sakr, Rita, Jensen, UB, Simard, Jacques,, Chung, Wendy,, Ruehl, I., Mazoyer, Sylvie, Christian F. Singer, Olga M Sinilnikova, B Barkardottir, Rosa, Hopper, John, Jones, J L, Schmutzler, Rita, Antoniou, A.C., Heikkinen, Tuomas,, Claudine Isaacs, Boutry-Kryza, N., M Buys, Saundra, Singer, CF, Papi, Laura,, Ding, Yuan C., Hardouin, Agnes,, Blanco, Ignacio, Lynch, Henry T., Mulligan, Anna,, Chun Ding, Yuan,, Ottini, L. (Laura), Andrulis, IL, Fricker, J.P. (Jean Pierre), Susan M. Domchek, Breast Cancer Family Registry, Pankratz, VS, Sherman, M, Stenmark Askmalm, Marie, Lynch, H.T., Side, L. (Lucy), Lazaro, Conxi,, Meijers-Heijboer, E.J. (Hanne), Goldgar, D., Nathanson, Katherine, Tea, Muy Kheng, Aittomaki, Kristiina,, McCann, E. (Emma), Karlan, B.Y. (Beth), Siranoush Manoukian, Nevanlinna, H, Ramus, Susan, Nelen, MR, Schoenbuchner, I., Terry, Mary B, Pascaline Berthet, Caligo, M.A. (Maria), Goldgar, D, Mark H. Greene, Ramus, Susan J., Nevanlinna, H. (Heli), Sylvie Mazoyer, Fink-Retter, A., Meijers-Heijboer, Hanne E J, Hanne E. J. Meijers Heijboer, Ramus, Susan J,, Moysich, Kirsten, Zaffaroni, Daniela, Kets, C.M., Pankratz, V.S., Preisler-Adams, Sabine, Seynaeve, C, Katherine L Nathanson, Hansen, Thomas V O, Simard, J., Easton, D.F., Nelen, Marcel, Sabine Preisler-Adams, Per Karlsson, Bernard, L, Godwin, Andrew K., Jensen, Uffe,, Mary Beth Terry, Radice, P, Gevensleben, Heidrun,, Jones, J.L. (J Louise), Weitzel, J.N. (Jeffrey), F Singer, Christian,, Weitzel, J.N., B Daly, Mary,, Chenevix-Trench, G., Daly, Mary, Sinilnikova, O.M., Terry, Mary Beth, Ding, Y.C., Glendon, G, Hansen, T.V.O. (Thomas), Virginie Caux Moncoutier, Lucy E. Side, Marie Stenmark Askmalm, Lazaro, C., Hansen, Thomas V. O., kConFab Investigators, Imyanitov, E, Montagna, Marco,, Christoph Engel, F Easton, Douglas, Skytte, Anne Bine, Moysich, K.B. (Kirsten), Healey, S. (Sue), Seynaeve, C., Fox, S.B. (Stephen), Bernard, Loris, Kauff, N., van der Luijt, Rob B., Beth Terry, Mary,, Couch, Fergus J, Mai, Phuong, Lebrun, M. (Marine), van der Luijt, Rob B,, Garcia, EBG, Barkardottir, Rosa B., Andrulis, Irene L, Alex Murray, Kristiina Aittomäki, Ganz, Patricia, Olga M. Sinilnikova, Wappenschmidt, B, Fiebig, B. (Britta), Zachary Fredericksen, Max Yan, Niederacher, D., H Greene, Mark,, Fricker, JP, Side, Lucy, Mia Gaudet, Fassy-Colcombet, Marion,, A Caligo, Maria, DAndrea, Emma, Greene, MH, Pujol, P. (Pascal), Pharoah, Paul D, Frost, Debra,, Karlan, Beth Y, Saundra M Buys, van der Luijt, R.B., Yan, M, Kauff, Noah,, Soller, M. (Maria), Tilanus-Linthorst, M.M.A., Verheus, M, Beth Terry, Mary, Georgia Chenevix-Trench, Osorio, Ana, Greene, M.H. (Mark), Offit, Kenneth, Houghton, C. (Catherine), T Lynch, Henry,, Nielsen, Finn, de Al Hoya, Miguel, M Lindor, Noralane,, Ozcelik, Hilmi,, Debra Frost, Agnès Hardouin, Barwell, J., Varon-Mateeva, Raymonda,, M Buys, Saundra,, Miron, A.F., Jones, JL, Thomas vO Hansen, Pharoah, Paul D.P., Jensen, Uffe B, Southey, Melissa, Janavicius, Ramunas, Lynch, H. (Henry), Barrowdale, D, O'Malley, F.P., Beattie, M, L Hopper, John,, de la Hoya, M., Spurdle, Amanda B,, Spurdle, Amanda B., Kast, K., Rob B van der Luijt, Tea, Muy-Kheng,, Heinritz, W, Nielsen, Finn C, Evans, D Gareth, Bonanni, B, Spurdle, AB, Greene, Mark, Soucy, P, van Os, T, Lynch, HT, Bernard, Loris,, Melissa C. Southey, Domchek, S.M. (Susan), Diana Eccles, Os, Theo,, Alexander F Miron, Olufunmilayo I. Olopade, Jasmine Bhatia, Moysich, K.B., Tomlinson, Gail E., Evans, DG, John, E.M. (Esther), Davidson, Rosemarie,, B Moysich, Kirsten, Jones, J. Louise, Rebbeck, Tim,, Gómez García, E.B., Hamann, Ute,, Rebbeck, Tim, Peissel, B. (Bernard), Neuhausen, Susan L., Savarese, A, Jeffrey N. Weitzel, K Godwin, Andrew,, Olufunmilayo I Olopade, Isaacs, C. (Claudine), Fink-Retter, Anneliese, Cattaneo, Elisa,, Davidson, R. (Rosemarie), Gomez Garcia, EncarnaB,, Isabelle Coupier, Yan, Max,, Fiebig, B, Engel, Christoph,, Schaefer, D, P OMalley, Frances, Lesley McGuffog, Olopade, Olufunmilayo I., K Schmutzler, Rita, Offit, Kenneth,, Antoniou, Antonis C, Longy, M., Munoz-Repeto, I, Kientz, C., Andrew K Godwin, T Lynch, Henry, Phuong L. Mai, Amanda E. Toland, Eccles, D., Pasini, B., Zaffaroni, D., Britta Fiebig, Thomassen, Mads,, Fox, Stephen,, Fox, S., Katherine L. Nathanson, Mazoyer, Sylvie,, Fiebig, Britta, Lynch, Henry T, Gross, Jenny,, Sherman, M., Gerdes, A.-M., Thomassen, Mads, Meijers-Heijboer, HEJ, Side, Lucy E., Tilanus-Linthorst, Madeleine, Jones, J Louise,, Kruse, TA, Bhatia, J., Preisler-Adams, S, Barbara Pasini, CIMBA, Weitzel, Jeffrey N, Anna Wachenfeldt, von, Rebbeck, T., Thomas V. O. Hansen, Kenneth Offit, Mai, P.L., Yuan Ding, Evans, D. Gareth, A Kruse, Torben, Gomez Garcia, EncarnaB, Noralane M Lindor, Sakr, Rita,, Imyanitov, E.N. (Evgeny), Eccles, D, Schmutzler, R.K. (Rita), Kets, C. Marleen, Rob B. van der Luijt, Fink-Retter, Anneliese,, Kets, C M, Murray, Alex,, M John, Esther,, Nathanson, K.L., Robson, M., Easton, Douglas F, Gómez García, Encarna, Emma D'Andrea, Chung, W, Coupier, I. (Isabelle), Stenmark-Askmalm, M. (M.), Christian F Singer, Niederacher, Dieter, Chenevix-Trench, G, Marine Lebrun, Zaffaroni, Daniela,, Arver, B., Schoenbuchner, I. (Ines), Moysich, KB, Ruehl, I, Marion Fassy-Colcombet, Tognazzo, S. (Silvia), Mulligan, Anna Marie,, Rhiem, K. (Kerstin), Jensen, Uffe B., McGuffog, Lesley,, Eeles, Ros,, Hansen, Thomas vO, Anna Wachenfeldt, von,, C Antoniou, Antonis,, Lund University., van Wijnen, J (Juul), D. Gareth Evans, Dominique Stoppa Lyonnet, Domchek, Susan M., Pankratz, Vernon S., Marcel R. Nelen, Offit, K., Couch, FJ, Domchek, Susan M,, Evans, D.G., Jensen, Uffe, Meijers-Heijboer, Hanne EJ, Dorkins, H. (Huw), Eeles, R, Nevanlinna, Heli, Ina Ruehl, Cook, Jackie, Schäfer, D, Dorkins, Huw,, Leone, M, Healey, S., John L. Hopper, Jacques Simard, Mary Beattie, B Moysich, Kirsten,, Wendy Chung, Savarese, A. (Antonella), Buys, Saundra M., Engel, C, Peissel, B., Meijers-Heijboer, Hanne, Simard, Jacques, C Antoniou, Antonis, Buys, S.M., S Pankratz, Vernon,, Sutter, C. (Christian), Toland, A.E. (Amanda), Verheus, M. (Martijn), Blanco, Ignacio,, Glendon, G., Y Karlan, Beth, Ding, Yuan, Bhatia, J, L Hopper, John, Stenmark-Askmalm, Marie, Louise Izatt, Szabo, Csilla, O'Malley, F.P. (Frances), L Neuhausen, Susan,, Sabine Preisler Adams, Wolfram Heinritz, Glendon, G. (Gord), Hardouin, A. (Agnès), Amanda E Toland, Nevanlinna, Heli,, Tuomas Heikkinen, Izatt, Louise,, Couch, Fergus J., Lindor, N.M., Couch, Fergus J,, Ramus, SJ, Benitez, J, Pertesi, M. (Maroulio), J. Louise Jones, Helen Gregory, Mulligan, Anna M, Houghton, C, Szabo, C, Kientz, C. (Caroline), Tilanus-Linthorst, Madeleine M A,, Couch, F.J., Izatt, L. (Louise), Nadia Boutry-Kryza, Skytte, Anne-Bine,, Jenny Gross, Montagna, Marco, Hamann, U., Duran, M, Tilanus - Linthorst, Madeleine, Ding, Yuan C, Toland, AE, Douglas F Easton, Rookus, Matti,, Pasini, B. (Barbara), Wang, X., Chenevix-Trench, Georgia,, Coupier, I, Szabo, C., Matti Rookus, Theo Os, Irene L Andrulis, Mulligan, Anna, Daly, MB, Eason, Jacqueline, Aittomaki, K, Tognazzo, S, Karlan, Beth Y., Dumont, Martine,, Verheus, M., Léone, M. (Mélanie), Godino, Javier, Laura Ottini, Hansen, Thomas V O,, Weitzel, Jeffrey N., Buys, S.S. (Saundra), Izatt, L. +999 morecore +1 more sourceDecoding metabolic dysfunction in cancer: foundations for early detection and personalized therapeutics
Frontiers in EndocrinologyThe global burden of cancer continues to rise despite significant advances in conventional oncology, underscoring the urgent need for novel approaches to prevention and early detection.Pradeep M. K. Nair, Ayyappan Palanisamy, Sekar Sivaranjani, Shanmugam Sudarshan, Sridhar Shubhakarini, Elangovan Karthika, Muniappan Devibala, Maruthanayagam Saranya, Thangavelu R., Saravanan P., Manickam Mahalingam, Janira Kumari, Karishma Silwal +12 moredoaj +1 more sourceSomatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen +5 morewiley +1 more source
