Results 51 to 60 of about 2,125,565 (269)

Vitamin D and Vitamin D‐binding protein and risk of bladder cancer: A nested case‐control study in the Norwegian Janus Serum Bank Cohort

Cancer Medicine, 2021
Background  High circulating levels of vitamin D (25(OH)D) are suggested to reduce the risk of urinary bladder cancer (BC), but the evidence is weak, and several studies lack sufficient adjustment for potential confounders (e.g., smoking, body mass index
Helga H. Hektoen, Trude E. Robsahm, Jo S. Stenehjem, Karol Axcrona, Ronnie Babigumira, Alison M. Mondul, Randi E. Gislefoss, Bettina K Andreassen   +7 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

HEAVY METAL CONTENTS IN COMMERCIAL FISHES CONSUMED IN UMUAHIA AND THEIR ASSOCIATED HUMAN HEALTH RISKS

EQA, 2020
This study evaluated the heavy metal contents in commercial fishes consumed in Umuahia and their associated health consequences. Trachunis symmetricus, Clupia pallassi, Micropogonias undulatus, Ictalumus punctalus, Scomber japonicus, Merluccius paradoxus,
Robert Ikechukwu Uroko, Amarachi Agbafor, Simeon Ikechukwu Egba, Oluomachi Nancy Uchenna, Rose Simon Adeyi Sangodare, Chinedu Paulinus Nwuke, Osisioma Kenneth Nwanosike   +6 more
doaj   +1 more source

Public health risk associated with the co-occurrence of aflatoxin B1 and ochratoxin A in spices, herbs, and nuts in Lebanon

Frontiers in Public Health, 2023
BackgroundAflatoxin B1 and ochratoxin A are mycotoxins produced by filamentous fungi that attack crops on field and storage. Both mycotoxins present a risk on public health since aflatoxin B1 is a hepatotoxic and hepatocarcinogenic agent while ochratoxin
Rouaa Daou, Maha Hoteit, Maha Hoteit, Maha Hoteit, Maha Hoteit, Khlood Bookari, Khlood Bookari, Karine Joubrane, Lydia Rabbaa Khabbaz, Lydia Rabbaa Khabbaz, Ali Ismail, Richard G. Maroun, André el Khoury   +12 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Analysis of Over 140,000 European Descendants Identifies Genetically Predicted Blood Protein Biomarkers Associated with Prostate Cancer Risk.

, 2019
Several blood protein biomarkers have been associated with prostate cancer risk. However, most studies assessed only a small number of biomarkers and/or included a small sample size.
Eeles, RA, Wu, L, Shu, X, Kote-Jarai, Z, PRACTICAL, CRUK, BPC3, CAPS, PEGASUS Consortia,, Guo, X, Zheng, W, Haiman, CA, Bao, J   +8 more
core   +1 more source

Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis

Nature Communications, 2016
Radiotherapy can induce fibrosis in cancer patients, limiting its use in clinical settings. Here, the authors identify a differentially methylated enhancer of the lipid kinase DGKA in fibroblasts from breast cancer patients developing fibrosis after ...
Christoph Weigel, Marlon R. Veldwijk, Christopher C. Oakes, Petra Seibold, Alla Slynko, David B. Liesenfeld, Mariona Rabionet, Sabrina A. Hanke, Frederik Wenz, Elena Sperk, Axel Benner, Christoph Rösli, Roger Sandhoff, Yassen Assenov, Christoph Plass, Carsten Herskind, Jenny Chang-Claude, Peter Schmezer, Odilia Popanda   +18 more
doaj   +1 more source

Alterations of Lipid Metabolism in Cancer: Implications in Prognosis and Treatment

Frontiers in Oncology, 2020
Cancer remains the second leading cause of mortality worldwide. In the course of this multistage and multifactorial disease, a set of alterations takes place, with genetic and environmental factors modulating tumorigenesis and disease progression ...
Lara P. Fernández, Marta Gómez de Cedrón, Ana Ramírez de Molina   +2 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Effect of polymorphism on IL1A to cancer susceptibility: Evidence based on 34,016 subjects

Artificial Cells, Nanomedicine, and Biotechnology, 2019
IL-1α is closely related to the development and metastasis of cancer, and its polymorphisms have been reported affecting the susceptibility of malignancy tumors, yet the conclusions are controversial.
Haoran Xia, Yiding Chen, Jialin Meng, Chaozhao Liang   +3 more
doaj   +1 more source