Results 41 to 50 of about 2,125,565 (269)

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Epidemiology and pathophysiology of cancer-associated thrombosis [PDF]

, 2010
Venous thromboembolism (VTE) is a common complication in patients with malignant disease. First recognised by Bouillard in 1823 and later described by Trousseau in 1844, multiple studies have since provided considerable evidence for a clinical ...
Pasi, J, S Noble, J Pasi, Noble, Simon Ian Robert, Pasi, J., Noble, S   +5 more
core   +1 more source

Obesity and Breast Cancer Risk in Men: A National Case-Control Study in England and Wales

, 2021
BackgroundBreast cancer is rare in men, and information on its causes is very limited from studies that have generally been small. Adult obesity has been shown as a risk factor, but more detailed anthropometric relations have not been investigated ...
Butlin, Alison, Swerdlow, AJ, Smith, B, Swerdlow, Anthony J, Griffin, J, Jones, Michael E, Swerdlow, MJ, Cooke, Rosie, Bruce, C, Griffin, James, Coulson, P, Coulson, Penny, Swerdlow, M Jill, Bruce, Cydney, Jones, ME, Butlin, A, Smith, Beverley, Cooke, R   +17 more
core   +1 more source

BARD1 deletion in a patient with suspected hereditary colorectal cancer

Human Genome Variation
Deleterious germline variants in the BRCA1-associated ring domain (BARD1) gene moderately elevate breast cancer risk; however, their potential association with other neoplasms remains unclear.
Nobue Takaiso, Issei Imoto, Akiyo Yoshimura, Akira Ouchi, Koji Komori, Hiroji Iwata, Yasuhiro Shimizu   +6 more
doaj   +1 more source

Cigarette smoking and mammographic breast density in post-menopausal women from the EPIC Florence cohort

Frontiers in Oncology
IntroductionCigarette smoking has been recognized as a risk factor for breast cancer (BC) also if the biological mechanism remains poorly understood.
Benedetta Bendinelli, Saverio Caini, Melania Assedi, Ilaria Ermini, Elisa Pastore, Luigi Facchini, Maria Antonietta Gilio, Giacomo Duroni, Miriam Fontana, Andrea Querci, Daniela Ambrogetti, Calogero Saieva, Giovanna Masala   +12 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

CYP3A variation, premenopausal estrone levels, and breast cancer risk.

, 2012
BACKGROUND: Epidemiological studies have provided strong evidence for a role of endogenous sex steroids in the etiology of breast cancer. Our aim was to identify common variants in genes involved in sex steroid synthesis or metabolism that are associated
Gibson, Lorna J, Jones, M, Tomlinson, IP, Ross, G, Folkerd, Elizabeth, Hillier, Stephen G, Schoemaker, M, Sawyer, Elinor, Folkerd, E, Kerin, M, Ross, Gillian, Peto, Julian, Swerdlow, A, Johnson, Nichola, Tomlinson, Ian P., Coupland, Ben, Fletcher, Olivia, Haynes, Ben, Kerin, Michael J, Williamson, Jill, Schoemaker, Minouk, Coupland, B, Simpson, Gemma, Palles, Claire, Ashworth, A, Dowsett, M, Houlston, RS, Johnson, N, Swerdlow, Anthony, Jones, Michael, Chilcott-Burns, S, Dos-Santos-Silva, Isabel, Williamson, J, Broderick, P, Zvelebil, M, Dowsett, Mitch, Walker, Kate, Fletcher, O, Houlston, Richard S, Dos Santos Silva, I, Kerin, Michael, Tomczyk, K, Walker, K, Palles, C, Zvelebil, Marketa, Gibson, Lorna J., Ashworth, Alan, Tomlinson, Ian P, Tomczyk, Katarzyna, Simpson, G, Orr, Nick; id_orcid, Orr, Nick, Orr, N, Swerdlow, Anthony J, Houlston, Richard S., Peto, J, Dos Santos Silva, Isabel, Hillier, Stephen G., Haynes, B, Hillier, SG, Sawyer, E, Broderick, Peter, Chilcott-Burns, Sarah, Gibson, LJ, Walker-Springett, Kate   +64 more
core   +1 more source

New Marker of Colon Cancer Risk Associated with Heme Intake: 1,4-Dihydroxynonane Mercapturic Acid [PDF]

, 2006
Background: Red meat consumption is associated with an increased risk of colon cancer. Animal studies show that heme, found in red meat, promotes preneoplastic lesions in the colon, probably due to the oxidative properties of this compound.
G. Gottardi, Gottardi, Gaëlle, N. Gasc, Peiro, Géraldine, S. Tache, Corpet, Denis, Cross, Amanda J., Taché, Sylviane, Bingham, Sheila A, A. J. Cross, D. E. Corpet, F. Gueraud, Gasc, Nicole, Pierre, Fabrice, Cross, Amanda J, Pierre, Fabrice H.F., Guéraud, Françoise, G. Peiro, Corpet, Denis E., S. A. Bingham, Bingham, Sheila A., F. Pierre   +21 more
core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Hematologic toxicity in BRCA1 and BRCA2 mutation carriers during chemotherapy: A retrospective matched cohort study

Cancer Medicine, 2019
Women who inherit a BRCA1 or BRCA2 mutation have an increased risk of breast cancer. Preliminary evidence suggests they may also have defects in bone marrow function.
Allison H. West, Hayley Knollman, James Dugan, Donald Hedeker, Elisabeth A. Handorf, Sarah M. Nielsen, Lisa C. Bealin, Lindsay G. Goldblatt, Heather Willems, Mary B. Daly, Anosheh Afghahi, Olufunmilayo I. Olopade, Peter J. Hulick, Elena Shagisultanova, Dezheng Huo, Elias Obeid, Jane E. Churpek   +16 more
doaj   +1 more source