Results 181 to 190 of about 7,457,740 (401)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Cancer Burden in Chinese Older Adults: Insights Into Incidence, Mortality, and Global Comparisons Using GLOBOCAN 2022

Aging Medicine
Objective To summarize the latest cancer burden among Chinese adults aged 60 years and older and compare it with the global average and four regions classified by Human Development Index (HDI).
Yuanjie Zheng, He Li, Qianru Li, Siyi He, Yi Teng, Mengdi Cao, Nuopei Tan, Jiachen Wang, Tingting Zuo, Tianyi Li, Wanqing Chen   +10 more
doaj   +1 more source

Global epidemiology of liver cancer 2022: An emphasis on geographic disparities

Chinese Medical Journal
. Background:. Liver cancer remains the sixth most commonly diagnosed cancer and the third leading cause of cancer-related deaths worldwide, causing a heavy burden globally.
Qianru Li, Chao Ding, Maomao Cao, Fan Yang, Xinxin Yan, Siyi He, Mengdi Cao, Shaoli Zhang, Yi Teng, Nuopei Tan, Jiachen Wang, Changfa Xia, Wanqing Chen, Jing Ni   +13 more
doaj   +1 more source

Cervical cancer screening behavior of reproductive women in Rajavithi Hospital [PDF]

, 2023
S Treesinchai, Charuwan Manmee
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Advances in 16S rRNA‐Based Microbial Biomarkers for Gastric Cancer Diagnosis and Prognosis

Microbial Biotechnology
Gastric cancer (GC) is a malignant tumour with high morbidity and mortality worldwide, and there is an urgent need for early diagnosis and precision treatment.
Yingying Wang, Xunan Qiu, Aining Chu, Jijun Chen, Lu Wang, Xiaohu Sun, Bengang Wang, Yuan Yuan, Yuehua Gong   +8 more
doaj   +1 more source

Does Patient Health and Hysterectomy Status Influence Cervical Cancer Screening in Older Women? [PDF]

, 2008
Helen I. Meissner, Jasmin A. Tiro, David A. Haggstrom, Grace L. Lu‐Yao, Nancy Breen   +4 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Radiologic Features of Small Pulmonary Nodules and Lung Cancer Risk in the National Lung Screening Trial: A Nested Case-Control Study

, 2017
Ying Liu, Hua Wang, Qian Li, Melissa McGettigan, Yoganand Balagurunathan, Alberto López García, Zachary Thompson, John Heine, Zhaoxiang Ye, Robert J. Gillies, Matthew B. Schabath   +10 more
openalex   +1 more source

High-Throughput Screening of Saliva for Early Detection of Oral Cancer: A Pilot Study [PDF]

, 2012
Ildikó Szántó, László Márk, Ágnes Bóna, Gábor Maász, B. Sandor, Gábor Gelencsér, Zsuzsanna Turi, Ferenc Gallyas   +7 more
openalex   +1 more source