Results 201 to 210 of about 846,985 (267)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Laypeople's Perceptions of Clinician Performance Metrics Based on Cancer Screening Attendance.

open access: yesJAMA Health Forum
Scherer LD   +10 more
europepmc   +1 more source

Assessment of ad hoc lung cancer screening at a safety net hospital. [PDF]

open access: yesJ Thorac Dis
Hudson M   +4 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Benefits and harms of lung cancer screening strategies in Argentina: a modeling study. [PDF]

open access: yesLancet Reg Health Am
Salgado MV   +5 more
europepmc   +1 more source

Cancer screening discrepancies among Black people in Canada: a scoping review. [PDF]

open access: yesBMC Public Health
Maduforo AN   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy