Results 161 to 170 of about 596,466 (219)

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Salinomycin is effective for clinically relevant radioresistant oral squamous cell carcinoma cancer cells and their cancer stem cell marker positive fraction. [PDF]

Med Int (Lond)
Saga R, Hosokawa Y, Fukumoto M.
europepmc   +1 more source

Programmable Functional Silicification of DNA Origami Nanostructures

Advanced Materials, EarlyView.
This work introduces additional functionality into silica‐coated DNA origami nanostructures using non‐standard silica precursors. A fluorescent precursor enables enhanced intracellular tracking, while a disulfide‐containing reagent yields redox‐responsive, degradable silica coatings.
Anna V. Baptist, Lasse Guericke, Philipp Mauker, Oliver Thorn‐Seshold, Amelie Heuer‐Jungemann   +4 more
wiley   +1 more source

Podoplanin and Selected Cancer Stem Cell or Stemness-Associated Markers in Oral Epithelial Dysplasia: A Structured Narrative Review of Their Role in Malignant Transformation and Risk Stratification. [PDF]

Reports (MDPI)
Dimitropoulou P, Fytros F, Charisi C, Syrioti A, Spantidakis N, Poulopoulos K, Fasoula M, Karagiannidis E, Poulopoulos A, Zisis V.   +9 more
europepmc   +1 more source

Elastomeric 3D‐Printed Microenvironments Enable Nanonewton Force Measurements in Healthy and Diseased Human Pluripotent Stem Cell‐Derived Neuroepithelial Cells

Advanced Materials, EarlyView.
We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena, Lucia Castillo Ransanz, Ruben H. Guis, Giulia Bergamaschi, Nanne J. Paauw, Urs Staufer, Vivi M. Heine, Angelo Accardo   +7 more
wiley   +1 more source

NAT10-dependent N⁴-acetylcytidine reprograms R-loops and promotes cancer stem cell growth. [PDF]

Cell Rep
Wu X, Wang D, Taori S, Wu W, Dixit D, Lv D, Mullett SJ, Gelhaus SL, Yuan F, Zhang P, Huang T, Yuan H, Wu Q, Rich JN.   +13 more
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Hedgehog/GLI1 regulates EMT and cancer stem cell properties via the GLI1-Bmi1 axis in diffuse large B-cell lymphoma. [PDF]

Sci Rep
Xiao H, Li C, Han Y, Gao J, Xu W, Xin P, Zhu X.   +6 more
europepmc   +1 more source

Decoding Synergistic Pathways in Bimetallic MOFs for Advanced Oxidation Processes

Advanced Materials, EarlyView.
This review presents a unified framework linking metal pairing and framework design with electronic structure, redox cycling, oxidant activation, reactive‐species generation, and catalytic performance across photocatalytic and oxidant‐based BMOF‐AOPs. The resulting design principles guide the development of hydrolytically stable and efficient BMOFs for
Karim El‐Naggar, Huayang Zhang, Shaobin Wang   +2 more
wiley   +1 more source

Mitochondrial Hijacking and MicroRNA Crosstalk: Cancer Stem Cell-Mediated Immune Evasion and Metabolic Plasticity in the Tumor Microenvironment. [PDF]

Cancers (Basel)
Ashrafian Bonab M, Salehi S, Aghababaie A, Amini A, Alizadeh H, Behnam B.   +5 more
europepmc   +1 more source