Results 1 to 10 of about 411,997 (358)
Emerging roles of cancer-testis antigenes, semenogelin 1 and 2, in neoplastic cells
Cancer-testicular Antigens (CTAs) belong to a group of proteins that under normal conditions are strictly expressed in a male’s reproductive tissues. However, upon malignisation, they are frequently re-expressed in neoplastic tissues of various origin. A
Oleg Shuvalov +5 more
doaj +1 more source
Mesenchymal stem cells lose the senescent phenotype under 3D cultivation
Background Three-dimensional (3D) cell culture is widely used in various fields of cell biology. In comparison to conventional two-dimensional (2D) cell culture, 3D cell culture facilitates a more accurate replication of the in vivo microenvironment ...
O. Krasnova +8 more
doaj +1 more source
Transgenic animals are an important tool in biotechnology, including the production of recombinant proteins in the milk. Traditionally, expression constructs are based on hybrid vectors bearing mammary gland specific regulatory elements from the α-casein
A. V. Smirnov +8 more
doaj +1 more source
A Single-Arm, Proof-Of-Concept Trial of Lopimune (Lopinavir/Ritonavir) as a Treatment for HPV-Related Pre-Invasive Cervical Disease [PDF]
BACKGROUND: Cervical cancer is the most common female malignancy in the developing nations and the third most common cancer in women globally. An effective, inexpensive and self-applied topical treatment would be an ideal solution for treatment of ...
A Kwara +48 more
core +9 more sources
Background ACTN4 is an actin-binding protein involved in many cellular processes, including cancer development. High ACTN4 expression is often associated with a poor prognosis.
Daria Kriger +6 more
doaj +1 more source
Evaluation of Xpert® MTB/RIF and ustar easyNAT™ TB IAD for diagnosis of tuberculous lymphadenitis of children in Tanzania : a prospective descriptive study [PDF]
Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF and Ustar EasyNAT TB IAD nucleic acid amplification assays, against ...
AT Cruz +39 more
core +3 more sources
The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase
The RING-finger protein Pirh2 is a p53 family-specific E3 ubiquitin ligase. Pirh2 also ubiquitinates several other important cellular factors and is involved in carcinogenesis. However, its functional role in other cellular processes is poorly understood.
Alexandra Daks +9 more
doaj +1 more source
Testing positive for human papillomavirus in routine cervical screening: examination of psychosocial impact [PDF]
Objective To examine the psychosocial impact of testing positive for high risk human papillomavirus (HPV) among women attending primary cervical screening.Design Cross sectional survey.Measures were taken at baseline and one week after the receipt of HPV
Cadman, L +5 more
core +1 more source

