Results 11 to 20 of about 279,076 (306)

FTIR Microspectroscopy Coupled with Two-Class Discrimination Segregates Markers Responsible for Inter- and Intra-Category Variance in Exfoliative Cervical Cytology. [PDF]

, 2008
Infrared (IR) absorbance of cellular biomolecules generates a vibrational spectrum, which can be exploited as a “biochemical fingerprint” of a particular cell type.
Fullwood, Nigel J., Olaug Grude, Azzedine Hammiche, Hubert M. Pollock, Martin, Francis L., Martin, Francis L, Singh, Maneesh N., Maneesh N. Singh, Francis L. Martin, Pollock, Hubert M., Martin-Hirsch, Pierre L., Pitt, Mark A., Michael J. Walsh, Grude, Olaug, Hammiche, Azzedine, Stringfellow, Helen F., Pierre L. Martin-Hirsch, Helen F. Stringfellow, Mark A. Pitt, Nigel J. Fullwood, Walsh, Michael J.   +20 more
core   +5 more sources

Multitask Deep Learning Model for Predicting Lymph Node Metastasis and Disease-Free Survival From Cytology Images in Bladder Cancer: A Multicenter Study With Pan-Cytology Validation. [PDF]

Adv Sci (Weinh)
Through self‐supervised pretraining and supervised fine‐tuning on large‐scale cytology image datasets, CytoNet predicts lymph node metastasis and survival. Across independent cohorts, this multitask framework demonstrates robust performance, improves risk stratification beyond radiological assessment, and provides interpretable evidence to support ...
Hong G, Jiang F, Xie Y, Huang X, Shen R, Wang Y, Zhu M, Wang H, Yang H, Nie Y, Lin Z, Chen R, Ouyang N, Lin T, Wu S.   +14 more
europepmc   +2 more sources

Emerging roles of cancer-testis antigenes, semenogelin 1 and 2, in neoplastic cells

Cell Death Discovery, 2021
Cancer-testicular Antigens (CTAs) belong to a group of proteins that under normal conditions are strictly expressed in a male’s reproductive tissues. However, upon malignisation, they are frequently re-expressed in neoplastic tissues of various origin. A
Oleg Shuvalov, Alyona Kizenko, Alexey Petukhov, Olga Fedorova, Alexandra Daks, Nikolai Barlev   +5 more
doaj   +1 more source

Alpha-actnin-4 (ACTN4) selectively affects the DNA double-strand breaks repair in non-small lung carcinoma cells

Biology Direct, 2022
Background ACTN4 is an actin-binding protein involved in many cellular processes, including cancer development. High ACTN4 expression is often associated with a poor prognosis.
Daria Kriger, Ksenia Novitskaya, Giomar Vasileva, Ekaterina Lomert, Nikolai D. Aksenov, Nikolai A. Barlev, Dmitri Tentler   +6 more
doaj   +1 more source

Mesenchymal stem cells lose the senescent phenotype under 3D cultivation

Stem Cell Research & Therapy, 2023
Background Three-dimensional (3D) cell culture is widely used in various fields of cell biology. In comparison to conventional two-dimensional (2D) cell culture, 3D cell culture facilitates a more accurate replication of the in vivo microenvironment ...
O. Krasnova, A. Kovaleva, A. Saveleva, K. Kulakova, O. Bystrova, M. Martynova, A. Domnina, J. Sopova, I. Neganova   +8 more
doaj   +1 more source

Evaluation of the α-casein (CSN1S1) locus as a potential target for a site-specific transgene integration

Scientific Reports, 2022
Transgenic animals are an important tool in biotechnology, including the production of recombinant proteins in the milk. Traditionally, expression constructs are based on hybrid vectors bearing mammary gland specific regulatory elements from the α-casein
A. V. Smirnov, G. V. Kontsevaya, T. A. Shnaider, A. M. Yunusova, N. A. Feofanova, L. A. Gerlinskaya, I. A. Serova, O. L. Serov, N. R. Battulin   +8 more
doaj   +1 more source

Association of cerebrovascular dysfunction with the development of Alzheimer’s disease-like pathology in OXYS rats

BMC Genomics, 2018
Background Cerebrovascular dysfunction plays a critical role in the pathogenesis of Alzheimer’s disease (AD): the most common cause of dementia in the elderly.
Natalia A. Stefanova, Kseniya Yi Maksimova, Ekaterina A. Rudnitskaya, Natalia A. Muraleva, Nataliya G. Kolosova   +4 more
doaj   +1 more source

Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome [PDF]

, 2009
Background To present a diagnostic evaluation and treatment strategy for serous adenocarcinoma of the ovary discovered during an in vitro fertilisation (IVF) sequence, and report on reproductive outcome after tumour resection and embryo transfer.
Noreen C. Gleeson (7952249), Shkrobot, LV, Mary N. Sheppard (7533800), David J. Walsh (2643388), Mary N Sheppard, Sills Eric, Noreen C Gleeson, Anthony PH Walsh (7952207), Gleeson, NC, Shkrobot Lyuda V, Lyuda V Shkrobot, Walsh, DJ, Sheppard, MN, Gleeson Noreen C, Eric Scott Sills, Anthony P H Walsh, Eric Scott Sills (6129536), Walsh David J, Sheppard Mary N, Walsh Anthony PH, Walsh, AP, David J Walsh, Lyuda V. Shkrobot (7952246), Sills, ES   +23 more
core   +1 more source

Usage of the cyto-genetics and cytology to identify the action mechanisms of two bio-fertilizers on Allium cepa meristematic cells

Bulletin of the National Research Centre, 2019
Background Bio-fertilizers as a safe alternative to the synthetic fertilizers come to the front in the agriculture requirements as they provide the planted crops with their nutrients to ensure high quality and productivity.
Rania T. Ali, Enas M. Abdel-Ghany, Fawzia I. Mohamed, Evon M. Hanna, Zeinab M. Elashery   +4 more
doaj   +1 more source

Malignancy risk analysis in patients with inadequate fine needle aspiration cytology (FNAC) of the thyroid [PDF]

, 2012
Background Thyroid fine needle aspiration cytology (FNAC) is the standard diagnostic modality for thyroid nodules. However, it has limitations among which is the incidence of non-diagnostic results (Thy1).
Mehanna, Hisham M., Weickert, Martin O., Hisham Mehanna, Al Maqbali Talib, Tedla Miroslav, Weickert, Martin O, Talib Al Maqbali, Al Maqbali, Talib, Mehanna Hisham, Weickert Martin O., Martin O Weickert, Tedla, Miroslav, Mehanna, Hisham; id_orcid, Miroslav Tedla   +13 more
core   +1 more source