Results 11 to 20 of about 194,896 (265)
Emerging roles of cancer-testis antigenes, semenogelin 1 and 2, in neoplastic cells
Cancer-testicular Antigens (CTAs) belong to a group of proteins that under normal conditions are strictly expressed in a male’s reproductive tissues. However, upon malignisation, they are frequently re-expressed in neoplastic tissues of various origin. A
Oleg Shuvalov +5 more
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Mesenchymal stem cells lose the senescent phenotype under 3D cultivation
Background Three-dimensional (3D) cell culture is widely used in various fields of cell biology. In comparison to conventional two-dimensional (2D) cell culture, 3D cell culture facilitates a more accurate replication of the in vivo microenvironment ...
O. Krasnova +8 more
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Transgenic animals are an important tool in biotechnology, including the production of recombinant proteins in the milk. Traditionally, expression constructs are based on hybrid vectors bearing mammary gland specific regulatory elements from the α-casein
A. V. Smirnov +8 more
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Background ACTN4 is an actin-binding protein involved in many cellular processes, including cancer development. High ACTN4 expression is often associated with a poor prognosis.
Daria Kriger +6 more
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Background Horizontal gene transfer, i.e. the acquisition of genetic material from nonparent organism, is considered an important force driving species evolution. Many cases of horizontal gene transfer from prokaryotes to eukaryotes have been registered,
Maria A. Daugavet +2 more
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Background Cerebrovascular dysfunction plays a critical role in the pathogenesis of Alzheimer’s disease (AD): the most common cause of dementia in the elderly.
Natalia A. Stefanova +4 more
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The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase
The RING-finger protein Pirh2 is a p53 family-specific E3 ubiquitin ligase. Pirh2 also ubiquitinates several other important cellular factors and is involved in carcinogenesis. However, its functional role in other cellular processes is poorly understood.
Alexandra Daks +9 more
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Objective: The study investigates how IVC and ET affect hypertensive phenotype in ISIAH rats. Methods: ISIAH rats born as the result of ET and IVC were compared with naturally conceived controls.
Tatyana N. Igonina +5 more
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