Results 221 to 230 of about 533,069 (264)

Targeting Colorectal Cancer Stem Cells Through Inhibition of the Fibroblast Growth Factor Receptor 4 Pathway with a Novel Antibody. [PDF]

open access: yesCancers (Basel)
Filocamo G   +14 more
europepmc   +1 more source

Cancer Stem Cells

2016
The cancer stem cell model in solid tumors has evolved significantly from the early paradigm shifting work highlighting parallels between the stem cell hierarchy in hematologic malignancies and solid tumors. Putative stem cells can dedifferentiated, be induced by context, and be the result of accumulated genetic mutations.
Wendy A, Woodward, Richard P, Hill
openaire   +2 more sources

Pancreatic Cancer Stem Cells

Journal of Clinical Oncology, 2008
Cellular heterogeneity in cancer was observed decades ago by studies in mice which showed that distinct subpopulations of cells within a tumor mass are capable of driving tumorigenesis. Conceptualized from this finding was the stem-cell hypothesis for cancer, which suggests that only a specific subset of cancer cells within each tumor is responsible ...
Cheong J, Lee   +2 more
openaire   +2 more sources

Colon Cancer Stem Cells

Current Protocols in Stem Cell Biology, 2008
AbstractThis unit describes protocols for working with colon cancer stem cells. To work with these cells one must start by generating single‐cell suspensions from human colon cancer tissue. These cell suspensions are sorted using flow cytometry–assisted cell sorting to fractionate the cells into tumor‐initiating and nontumor‐initiating subsets.
Antonija, Kreso   +1 more
openaire   +2 more sources

Colon cancer stem cells

Gut, 2007
Colorectal cancer (CRC) is the third most common form of cancer and the second cause of cancer-related death in the Western world, leading to 655,000 deaths worldwide per year (Jemal et al. in CA Cancer J Clin 56:106–130, 2006). Despite the emergence of new targeted agents and the use of various therapeutic combinations, none of the treatment options ...
L, Ricci-Vitiani   +4 more
openaire   +2 more sources

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