Results 221 to 230 of about 546,265 (263)

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Targeting Wnt3a and Loxl2 Synergistically Induces Ferroptosis in Liver Cancer Stem Cells and Suppresses Tumorigenesis. [PDF]

Cancer Sci
Ren G, Cong Q, Wang J, Gao W, Guan Y, Zhu L, Zhu Y.   +6 more
europepmc   +1 more source

Enrichment of colon cancer stem cells via polymeric porous filters with different zeta potentials. [PDF]

Regen Biomater
Sung TC, Hung LC, Gao M, Lin X, Yang M, Kang X, Tian Z, Wang T, Gong J, Pan J, Lee HH, Higuchi A.   +11 more
europepmc   +1 more source

Targeting cancer stem cells predicts response and reverses chemoresistance in ascites-derived ovarian cancer organoids. [PDF]

BMC Med
Zhang X, Zhang W, Cui Y, Zhang Q, Wan D, Li N, Zhang K, Guo H.   +7 more
europepmc   +1 more source

BNIP3L/BNIP3-Mediated Mitophagy Contributes to the Maintenance of Ovarian Cancer Stem Cells. [PDF]

J Cell Mol Med
Li N, Pal Khaket T, Yang Y, Wang L, Cai S, Li A, Wani E, Miao J, Zhang N, Zheng Q, Zhang J, Liu X, Karuppaiyah S, Pei D, Wang QE.   +14 more
europepmc   +1 more source

Gedunin Impacts Pancreatic Cancer Stem Cells Through the Sonic Hedgehog Signaling Pathway. [PDF]

Pharmaceuticals (Basel)
Perez K, Rodriguez S, Barragan J, Narayanan P, Ruiseco A, Rajkumar P, Ramirez N, Vasquez V, Lakshmanaswamy R, Subramani R.   +9 more
europepmc   +1 more source

Cancer stem cells in hepatocellular carcinoma: platforms, updates, challenges and future perspectives. [PDF]

Cancer Biol Med
Lu J, O DC, Tsui YM, Ng IO.
europepmc   +1 more source

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“To Be or Not to Be...” Cancer Stem Cells or Not Cancer Stem Cells..

Postdoc Journal, 2013
Cancer stem cells (CSCs) are defined as cancer cells with self-renewal capacity. These cells represent a small subpopulation endowed with the ability to form new tumors when injected in mice. Membrane markers and cancer stem cell assays have been used to identify and characterize these cells.
Bianca Ho, Laura Rosenthal, Zafira Castano   +2 more
openaire   +1 more source

Stem cells and cancer

Seminars in Cancer Biology, 2007
The cell of origin of cancer has been a strongly debated topic through out the history of cancer research. This review provides a historic framework and a synopsis of how the theories of cancer initiation and progression evolved from early times to the present day.
JeanMarie, Houghton, Alexei, Morozov, Iva, Smirnova, Timothy C, Wang   +3 more
openaire   +2 more sources