Results 241 to 250 of about 468,736 (292)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Erratum to "Exploring the universal healthy human gut microbiota around the World". [PDF]

Comput Struct Biotechnol J
Piquer-Esteban S, Ruiz-Ruiz S, Arnau V, Diaz W, Moya A.   +4 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

A Roadmap to Transform Lung Cancer Outcomes: Priorities in Biology, Therapeutic Innovation, Early Detection, Prevention, and Interception. [PDF]

Cancer Discov
Winslow MM, Ahmed MA, Berg CD, Black JRM, Downward J, Govindan R, Herbst RS, Heymach JV, Jaffee EM, Kraut N, Merad M, Meyerson M, Pandya T, Politi K, Rao AV, Rudin CM, Soria JC, Tang YJ, Wong KK, Yap TA, Swanton C, AACR Lung Cancer Task Force.   +21 more
europepmc   +1 more source

Disrupting the Undruggable: Emerging Modalities for Targeting Protein-Protein Interactions in Oncology. [PDF]

Biology (Basel)
El-Tanani M, Rabbani SA, Wali AF, El-Tanani Y, Sharma S.   +4 more
europepmc   +1 more source

Antagonists of platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) as rationale and therapeutic potential of combination cancer therapy. [PDF]

Am J Clin Exp Immunol
Qian H, Wang Y, Appiah-Kubi K.
europepmc   +1 more source

Immunotherapy 3.0: Breakthroughs Steering the Next Generation of Cancer Control. [PDF]

Cancer Rep (Hoboken)
Obeagu EI.
europepmc   +1 more source

Adaptive therapy and its challenges. [PDF]

Evol Med Public Health
Wu J, Strobl MAR, Scott JG.
europepmc   +1 more source

Contrasting Features of Papillary and Chromophobe Renal Cell Carcinoma Revealed by Whole-Genome Sequencing. [PDF]

Mol Cancer Res
Culliford R, Mills C, Chubb D, Kinnersley B, Sud A, Cornish AJ, Browning L, Lawrence SED, Bentham R, Frangou A, Gruber AJ, Litchfield K, Wedge DC, Larkin J, Turajlic S, Houlston RS.   +15 more
europepmc   +1 more source