Results 11 to 20 of about 11,697,511 (307)

Targeting NaPi2b in ovarian cancer. [PDF]

open access: yes, 2023
Novel biomarkers are needed to direct new treatments for ovarian cancer, a disease for which the standard of care remains heavily focused on platinum-based chemotherapy.
Drapkin, R   +3 more
core   +1 more source

Effects of MRE11 on Apoptosis and Proliferation of Esophageal Squamous Cancer Cells

open access: yesZhongliu Fangzhi Yanjiu, 2022
Objective To investigate the effect of MRE11 on the proliferation and apoptosis of esophageal squamous cancer cells and its molecular mechanism. Methods MRE11 expression was downregulated by MRE11 siRNA transfection in esophageal squamous cancer cells ...
ZHANG Yan   +4 more
doaj   +1 more source

Consensus of Chinese experts on multidisciplinary team of gynecological malignant tumors (2022 edition)

open access: yesZhongguo aizheng zazhi, 2022
Recently, new strategies for the integrated treatment of gynecological malignancies have been improved along with the development of reproductive oncology and hereditary tumors concepts.
Committee of China Anti-Cancer Association, Multidisciplinary Cancer Diagnosis and Treatment Committee of Chinese Medical Doctor Association The Society of Gynecological Cancer of China Anti-Cancer Association, Multidisciplinary Diagnosis and Treatment (MDT)
doaj  

Therapeutic and prophylactic gastrectomy in a family with hereditary diffuse gastric cancer secondary to a CDH1 mutation: a case series

open access: yesWorld Journal of Surgical Oncology, 2018
Background Gastric cancer is the fifth most prevalent and the third most lethal cancer worldwide, causing approximately 720,000 deaths annually. Although most cases of gastric cancers are sporadic, one of its inherited forms, hereditary diffuse gastric ...
Olsi Gjyshi   +7 more
doaj   +1 more source

Adult-type granulosa cell tumor of the testis: report of a case and review of literature

open access: yesThe Pan African Medical Journal, 2017
Granulosa cell tumors is classified into juvenile and adult types and comprise less than 5% of ovarian tumors in women and are much rarer in men which only 45 have been previously reported.
Meriem Elbachir   +8 more
doaj   +1 more source

Efficacy of Negative Pressure Wound Therapy Followed by Delayed Primary Closure for Abdominal Wounds in Patients with Lower Gastrointestinal Perforations: Multicenter Prospective Study

open access: yesJournal of the Anus, Rectum and Colon, 2020
Objectives: The efficacy of negative pressure wound therapy (NPWT) and its application to severely contaminated wounds sustained during surgery remain to be established. Here, we evaluated the efficacy of utilizing NPWT until delayed primary closure (DPC)
Hirofumi Ota   +15 more
doaj   +1 more source

Molecular genomic features associated with in vitro response of the NCI‐60 cancer cell line panel to natural products

open access: yesMolecular Oncology, 2021
Natural products remain a significant source of anticancer chemotherapeutics. The search for targeted drugs for cancer treatment includes consideration of natural products, which may provide new opportunities for antitumor cytotoxicity as single agents ...
Julia Krushkal   +10 more
doaj   +1 more source

China National Lung Cancer Screening Guideline with Low-dose Computed Tomography (2023 Version)

open access: yesChinese Journal of Lung Cancer, 2023
Lung cancer is the leading cause of cancer-related death in China. The effectiveness of low-dose computed tomography (LDCT) screening has been further validated in recent years, and significant progress has been made in research on identifying high-risk ...
Chinese Expert Group on Early Diagnosis and Treatment of Lung Cancer   +1 more
doaj   +1 more source

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer [PDF]

open access: yes, 2013
IntroductionBreast cancer remains a significant scientific, clinical and societal challenge. This gap analysis has reviewed and critically assessed enduring issues and new challenges emerging from recent research, and proposes strategies for translating ...
Gee, Julia M. W.   +645 more
core   +3 more sources

Advances in immunotherapy for MMR proficient colorectal cancer.

open access: yes, 2023
Survival in mismatch-repair proficient (MMRp) metastatic colorectal cancer (mCRC) remains poor and chemotherapy is the mainstay of treatment. Immunotherapy has demonstrated durable responses and a favourable side-effect profile in various cancer types ...
Gerlinger, M   +3 more
core   +1 more source

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