Results 201 to 210 of about 3,468,016 (309)

Programmable three‐state nanoreactor for spatiotemporally controlled tumor therapy

BMEMat, EarlyView.
The OMVs are shielded with a biocompatible Da–Ca shell, which prolongs its circulation period and promotes intratumoral accumulation. Importantly, the biocompatible Da–Ca shell can be controllably disintegrated in tumor microenvironment by using laser irradiation, generating in situ hyperthermia and releasing Ca2+.
Guihong Lu, Peng Ye, Xiaoyan Li, Ke Ma, Chengliang Lyu, Kai Zhang, Ran Luo, Yang Ji, Shiqi Mei, Fan Zhang, Jinxie Zhang, Lin Mei, Hui Tan   +12 more
wiley   +1 more source

Promising Cancer Vaccine for Glioblastoma Therapy: A Focus on mRNA Vaccine. [PDF]

Cancer Med
Barati S, Ghoflchi S, Hosseinzadeh P, Pouramini S, Hosseini H, Jalili-Nik M.   +5 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Combined prostate cancer vaccine plus immune checkpoint inhibition synergizes to eliminate prostate cancer. [PDF]

iScience
Carreno-Galeano G, Dubey S, Iczkowski KA, Van Veldhuizen P, Anele UA, Messer JC, Ankem MK, Karan D.   +7 more
europepmc   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Precise regulation of cancer vaccine and immune checkpoint inhibitor synergy potentiates immunotherapy with reduced immune-related pneumonitis. [PDF]

Mater Today Bio
Wang Z, Zuo S, Wan X, He Y, Jiang X, Fan G, Liu Q, Shao D, Liu Q, Zhang Y.   +9 more
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

AutoEpiCollect 2.0: A Web-Based Machine Learning Tool for Personalized Peptide Cancer Vaccine Design. [PDF]

Molecules
Kim CA, Shelton N, Samudrala M, Savsani K, Dakshanamurthy S.   +4 more
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Preclinical evaluation of a CCL19 immune-potentiated DNA cancer vaccine. [PDF]

Cancer Immunol Immunother
Kofoed SV, Barrio-Calvo M, Pavlidis MA, Kleine-Kohlbrecher D, Lausen M, Lunabjerg-Vestergaard C, Viborg N, Garde C, Rønø B, Friis S.   +9 more
europepmc   +1 more source