Results 181 to 190 of about 198,762 (311)

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

Targeting Telomerase in Cancer: Vaccine-Based Strategies, Clinical Evidence, and Synergy with Immunotherapy. [PDF]

Diseases
Baliou S, Tzatzarakis MN, Tsantes AG, Vakonaki E, Ioannou P, Kyriakakis M, Hatzidaki E, Pelagiadis I, Stiakaki E, Tsatsakis A.   +9 more
europepmc   +1 more source

Therapeutic dendritic cell vaccination against human papillomavirus

, 2009
Cervical cancer, which is caused by infection with human papillomavirus (HPV), is the second most common cancer among women worldwide, leading to 230000 deaths annually.
Nurkkala Karlsson, Merja
core  

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Recent advances in lipid nanoparticles for cancer vaccine delivery: Challenges and future perspectives. [PDF]

Int J Pharm X
Hasan N, Aftab M, Ikram S, Mustofa AZ, Sriwidodo S, Darusman HS, Amir MN, Tockary TA, Uchida S.   +8 more
europepmc   +1 more source

Risk of venous thromboembolism after SARS‐CoV‐2 vaccination—Evidence from genome‐wide association study and population‐based observational study

British Journal of Clinical Pharmacology, EarlyView.
Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind, Niclas Eriksson, Marco Cavalli, Yiyi Xu, Fredrik Nyberg, Anders Sundström, Mia Wadelius, Pär Hallberg   +7 more
wiley   +1 more source

Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms. [PDF]

Small Sci
Ahn W, Lee Y, Nam GH, You JB, Lee EJ.
europepmc   +1 more source

Microsomal membranes from antigen presenting cells present antigenic peptides to T cells: a novel approach in vaccine development.

, 2010
PhDThe study of the immune system has provided insight in the mechanism of protection induced by vaccination; primarily that most clinically protective vaccines are potent in generating neutralizing antibody responses.
Sofra, Vasiliki
core  

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Combined prostate cancer vaccine plus immune checkpoint inhibition synergizes to eliminate prostate cancer. [PDF]

iScience
Carreno-Galeano G, Dubey S, Iczkowski KA, Van Veldhuizen P, Anele UA, Messer JC, Ankem MK, Karan D.   +7 more
europepmc   +1 more source