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Hematology/Oncology Clinics of North America, 2019
Cancer vaccines are a promising strategic approach within the rapidly growing field of immuno-oncology. Therapeutic cancer vaccines are distinct from prophylactic vaccines and vary by both target antigen and vaccine platform. There are currently 3 FDA-approved therapeutic cancer vaccines: intravesical BCG live, sipuleucel-T, and T-VEC.
Peter J, DeMaria, Marijo, Bilusic
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Cancer vaccines are a promising strategic approach within the rapidly growing field of immuno-oncology. Therapeutic cancer vaccines are distinct from prophylactic vaccines and vary by both target antigen and vaccine platform. There are currently 3 FDA-approved therapeutic cancer vaccines: intravesical BCG live, sipuleucel-T, and T-VEC.
Peter J, DeMaria, Marijo, Bilusic
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Expert Opinion on Therapeutic Targets, 2004
Cancer vaccines - a dream or a reality? There is no doubt that a time will come when this new approach to cancer treatment will provide opportunities that will be both complementary and synergistic with existing treatments. Novelty is often linked to risk, and if there is a given medical field that desperately needs therapeutic improvement, cancer is ...
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Cancer vaccines - a dream or a reality? There is no doubt that a time will come when this new approach to cancer treatment will provide opportunities that will be both complementary and synergistic with existing treatments. Novelty is often linked to risk, and if there is a given medical field that desperately needs therapeutic improvement, cancer is ...
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2012 Sixth International Conference on Complex, Intelligent, and Software Intensive Systems, 2012
Cancer vaccine research is a hot topic for medical treatments of cancer. Identification of candidate antigenic stimuli for the vaccine is already improved using immune-informatics. Subsequent test in vivo are expensive and time consuming. There is an increasing request to a modeling approach to speed up this phase of vaccine research.
Francesco Pappalardo 0001, Santo Motta
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Cancer vaccine research is a hot topic for medical treatments of cancer. Identification of candidate antigenic stimuli for the vaccine is already improved using immune-informatics. Subsequent test in vivo are expensive and time consuming. There is an increasing request to a modeling approach to speed up this phase of vaccine research.
Francesco Pappalardo 0001, Santo Motta
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The Possibilities of a Vaccine for Cancer [PDF]
Ca-A Cancer Journal for Clinicians, 1969 exaly +3 more sources
Vaccinations in children with cancer
Vaccine, 2010Children with cancer may be immunocompromised as a result of their primary underlying disease and/or the use of prolonged and intensive chemotherapy administered with or without irradiation. The damage to the immune system varies with the age of the patient, the type of cancer, and the intensity of the chemotherapy used to treat it.
S. Esposito +3 more
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Surgical Oncology Clinics of North America, 2007
Therapeutic cancer vaccines target the cellular arm of the immune system to initiate a cytotoxic T-lymphocyte response against tumor-associated antigens. Immunotherapy offers one of the few therapeutic options that reproducibly leads to a subset of patients with long-term remissions (seemingly cures) of widely metastatic disease.
Lilah F, Morris, Antoni, Ribas
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Therapeutic cancer vaccines target the cellular arm of the immune system to initiate a cytotoxic T-lymphocyte response against tumor-associated antigens. Immunotherapy offers one of the few therapeutic options that reproducibly leads to a subset of patients with long-term remissions (seemingly cures) of widely metastatic disease.
Lilah F, Morris, Antoni, Ribas
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Current Opinion in Pharmacology, 2019
Cancer vaccines based on synthetic peptides are a safe, well-tolerated immunotherapy able to specifically stimulate tumor-reactive T cells. However, their clinical efficacy does not approach that achieved with other immunotherapies such as immune checkpoint blockade.
Calvo Tardon, Marta +4 more
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Cancer vaccines based on synthetic peptides are a safe, well-tolerated immunotherapy able to specifically stimulate tumor-reactive T cells. However, their clinical efficacy does not approach that achieved with other immunotherapies such as immune checkpoint blockade.
Calvo Tardon, Marta +4 more
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Seminars in Immunology, 2010
The recent FDA approval of sipuleucel-T (Provenge), a patient-specific immunotherapy for androgen-independent prostate cancer developed by Dendreon Corporation, has provided support for the concept of cellular immunotherapy as an approach to cancer treatment.
Thomas W, Dubensky, Steven G, Reed
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The recent FDA approval of sipuleucel-T (Provenge), a patient-specific immunotherapy for androgen-independent prostate cancer developed by Dendreon Corporation, has provided support for the concept of cellular immunotherapy as an approach to cancer treatment.
Thomas W, Dubensky, Steven G, Reed
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Current Opinion in Gastroenterology, 2002
The development of vaccines to induce tumor-specific immunity in patients with cancer has as emerged as a major area of investigation. The identification of antigens uniquely expressed by tumor cells and a heightened understanding of tumor immunology have resulted in efforts to activate host immunity to recognize and reject tumor cells.
Virginia F, Borges +2 more
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The development of vaccines to induce tumor-specific immunity in patients with cancer has as emerged as a major area of investigation. The identification of antigens uniquely expressed by tumor cells and a heightened understanding of tumor immunology have resulted in efforts to activate host immunity to recognize and reject tumor cells.
Virginia F, Borges +2 more
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Vaccines in the treatment of cancer
American Journal of Health-System Pharmacy, 1995The development of vaccines for treating cancer is discussed. The central hypothesis behind active specific immunotherapy for cancer is that tumor cells express unique antigens that tell the immune system that something about these cells is foreign. A vaccine is a way of delivering an antigen to the immune system such that immune cells recognize the ...
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