Results 261 to 270 of about 198,762 (311)

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Combination therapy with alisertib enhances the anti-tumor immunity induced by a liver cancer vaccine. [PDF]

iScience
Xue F, Liu J, Wu J, Li X, Zhu N, Tang S, Zhang M, Duan H, Wang R, Zhang J.   +9 more
europepmc   +1 more source

Targeting B7-H3 enhances the efficacy of neoantigen-based cancer vaccine in combination with radiotherapy. [PDF]

NPJ Vaccines
Ke TW, Chen CY, Chen WT, Tsai YY, Chiang SF, Huang CH, Lin YS, Chen TH, Chen TW, Liang JA, Chao KSC, Huang KC.   +11 more
europepmc   +1 more source

A cowpea mosaic virus adjuvant conjugated to liposomes loaded with tumor cell lysates as an ovarian cancer vaccine. [PDF]

Nat Commun
Zhao Z, Ledezma DK, Affonso de Oliveira JF, Omole AO, Steinmetz NF.   +4 more
europepmc   +1 more source

Transdermal delivery of PeptiCRAd cancer vaccine using microneedle patches. [PDF]

Bioact Mater
D'Amico C, Fusciello M, Hamdan F, D'Alessio F, Bottega P, Saklauskaite M, Russo S, Cerioni J, Elbadri K, Kemell M, Hirvonen J, Cerullo V, Santos HA.   +12 more
europepmc   +1 more source

Off-The-Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma. [PDF]

Adv Mater
Moura LI, Malfanti A, Matos AI, Peres C, Armiñán A, Duro-Castaño A, Conejos-Sánchez I, Medel M, Đorđević S, Carrascosa P, Carreira B, Acúrcio RC, Xavier-Ferreira H, Hernández-Barranco A, Castellano E, Roselló E, Machado JC, Peinado H, Vicent MJ, Florindo HF.   +19 more
europepmc   +1 more source

Targeting PI3K Signaling to Overcome Tumor Immunosuppression: Synergistic Strategies to Enhance Cancer Vaccine Efficacy. [PDF]

Vaccines (Basel)
Cui R, Luo Z, Zhang X, Yu X, Yuan G, Li X, Xie F, Jiang O.   +7 more
europepmc   +1 more source

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Cancer Vaccines

Current Protocols in Human Genetics, 1997
AbstractThis unit describes the use of retroviral vectors that can be successfully employed for gene transfer into both primary tumor cultures and established cell lines. The unit includes procedures for assaying the stability of the vaccine following gene transfer.
T F, Greten, E M, Jaffee
  +8 more sources

Cancer vaccines

Seminars in Oncology Nursing, 2003
To provide a review of cancer vaccines, how they work, and the current state of the science underlying these treatments.Research studies, review articles, book chapters, personal communications.Vaccines have been studied in a variety of malignancies; however, melanoma has provided the best tumor model for vaccination.
Paula M, Muehlbauer, Douglas J, Schwartzentruber   +1 more
openaire   +4 more sources

Cancer vaccines

Vaccine, 2001
Cancer vaccines have been extensively tested in animal models, and in humans. Initial studies focused on first generation vaccines based on whole cell preparations or tumor lysates derived from autologous or allogeneic tumors. Clinical studies conducted with such candidate vaccines contributed to establish the feasibility of immunizing cancer patients ...
R F, Rousseau, C, Hirschmann-Jax, S, Takahashi, M K, Brenner   +3 more
openaire   +4 more sources