Results 241 to 250 of about 3,468,016 (309)

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Enhancing DC cancer vaccine by allogeneic MHC class II expression and Treg depletion. [PDF]

JCI Insight
Seishima N, Becker W, Olkhanud PB, Maeng HM, Lopez-Lago MA, Williams WV, Berzofsky JA.   +6 more
europepmc   +1 more source

Under‐Explored Species, Breeds and Cell Types With Potential for Cultivated Meat Production

Food Bioengineering, EarlyView.
This graphical abstract illustrates how the strategic selection of overlooked cell lines from novel species and specific agricultural breeds can help overcome current manufacturing bottlenecks in cultivated meat production. The schematic links the concept of an ‘ideal cell line’ to four key bioprocessing and product advantages that can be optimised ...
William Gordon‐Petrovskii, Maanasa Ravikumar, Travis Callue, Maria Laura Vieri, Michael Sulu, Gary J. Lye, Mariana Petronela Hanga   +6 more
wiley   +1 more source

Lung cancer vaccine strategies: exploring the spectrum from traditional to RNA-based platforms. [PDF]

Front Bioeng Biotechnol
Pazoki A, Dadfar S, Alirezaee A, Oksenych V, Haghmorad D.   +4 more
europepmc   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

FlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu, Yubing Hu, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

A Nanomodulator Enhances Radiotherapy-Induced In Situ Cancer Vaccine by Promoting Antigen-Presenting of Tumor-Associated Macrophage. [PDF]

Adv Sci (Weinh)
Zhao X, Li M, Li J, Han Y, Gong Y, Zhang Z, Shi J, Jin CY, Liu J, Si P.   +9 more
europepmc   +1 more source

Balancing Antigen Loading on Gold Nanoparticles: Implications for Future Cancer Vaccine Strategies. [PDF]

Chemistry
Ghirardello M, Guerreiro A, Bretón C, Compañón I, Zabalza J, Mangini V, Peregrina JM, Bernardes GJL, Corzana F.   +8 more
europepmc   +1 more source

Human Papillomavirus-Related Cancer Vaccine Strategies. [PDF]

Vaccines (Basel)
Cai X, Xu L.
europepmc   +1 more source

Health System Resilience and Afghan Refugee Health in Pakistan: An Exploratory Study of Challenges and Pathways to Inclusion

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Pakistan has hosted Afghan refugees for more than four decades, in one of the world's most protracted displacements of people. Afghan refugees receive health services through United Nations High Commissioner for Refugees (UNHCR) and non‐governmental organisation (NGO) supported programmes alongside public sector facilities at every tier.
Zahid Ali Memon, Asma Ummad, Amina Olabi, Natasha Palmer, Sophie Witter   +4 more
wiley   +1 more source

Promising future of breast cancer vaccine asking for multidisciplinary collaboration: a literature review. [PDF]

Front Cell Dev Biol
Zhang Z, Li M, Zhang L, Wang M, Liu D, Tang S, Li Y, Fang X, Ren S.   +8 more
europepmc   +1 more source